The Reactions that Increase and Decrease Co2 Concentration During Viral Infection Like Covid-19 Virus: the Effect of Vitamin C

Yıl 2020, Cilt: 3 Sayı: 1, 14 - 19, 20.06.2020

Ezman Karabulut Engin Yılmaz

Öz

It is known that some patients do not show any disease symptoms. The human body can resist all kinds of viruses. However, the immune system must be resistant to this virus. In viral infection treatment processes, developing an antiviral drug against the virus should be the second option. The first option is to support the immune system, so as to block propagation medium of virus. The main purpose of this study is to determine whether the vitamin C given to the patient is sufficient to prevent the formation of low pH environment that accelerates spread of virus. For this reason, the CO2 molecule must be easily separated from human body. Viral RNA viruses indirectly affect the carbonic anhydrase-9 enzyme, working on transmembrane, known as a pH-regulating enzyme. Interaction of vitamin C with oxidants has been shown to inhibit carbonic anhydrase-9 enzyme reactions. As a result of the interaction of vitamin C with oxidants, newly formed molecular formations affect carbonic anhydrase-9 enzyme reaction. This new molecule blocks the amino acids to which zinc, which is the coenzyme of the enzyme, binds.

Anahtar Kelimeler

Covid-19, Carbonic Anhydrase Enzyme, , Vitamin C

Teşekkür

The authors are grateful to Bitlis Eren University for Gaussian09W and GaussView5.0 Program support and to the Scientific and Technological Research Council of Turkey for TR-Grid facilities. Also the authors thank Dr. Metin KARAGÖZ for his valuable comments.

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