Evaluation of antimicrobial and antibiofilm activities of some Phytolacca americana L. extracts

Gülbeyaz Dökmeci; Kevser Taban; İpek Süntar; Osman Tugay; Berrin Özçelik

doi:10.12991/jrespharm.1629289

Evaluation of antimicrobial and antibiofilm activities of some Phytolacca americana L. extracts

Abstract

Antimicrobial resistance remains a significant global challenge across various fields. To solve this problem, researchers are working on developing antimicrobial agents, antiseptics, and disinfectants with different formulations. In this study, methanol (MeOH) extracts of Phytolacca americana L. fruits and leaves, were evaluated for their both antimicrobial and antibiofilm activities using microdilution method and antibiofilm assay against bacteria and fungi including Staphylococcus aureus, Streptococcus mutans, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii, Candida albicans, C. parapsilosis, C. krusei, Trichophyton rubrum, Epidermophyton floccosum, and Microsporum gypseum.. According to the activity studies, extracts displayed 32-128 µg/mL MICs against tested bacteria and fungi. In the microduliton method; inhibition curves of IC50 obtained by the resazurin microplate assay for the extracts showed results in the range of 12-41 μg/mL.

Keywords

Supporting Institution

Gazi University

Project Number

TYL-2024-9449

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Details

Primary Language

English

Subjects

Pharmaceutical Microbiology

Journal Section

Research Article

Authors

Gülbeyaz Dökmeci ^*
0000-0001-7562-7842
Türkiye

Kevser Taban
0000-0001-8620-6402
Türkiye

İpek Süntar
0000-0003-4201-1325
Türkiye

Osman Tugay
0000-0003-3980-7648
Türkiye

Berrin Özçelik
0000-0003-0525-1186
Türkiye

Publication Date

January 11, 2026

Submission Date

January 29, 2025

Acceptance Date

April 13, 2025

Published in Issue

Year 2026 Volume: 30 Number: 1

DOI

https://doi.org/10.12991/jrespharm.1629289

IZ

https://izlik.org/JA42BP46XZ

Cite

RIS / Bibtex

APA

Dökmeci, G., Taban, K., Süntar, İ., Tugay, O., & Özçelik, B. (2026). Evaluation of antimicrobial and antibiofilm activities of some Phytolacca americana L. extracts. Journal of Research in Pharmacy, 30(1), 51-59. https://doi.org/10.12991/jrespharm.1629289

AMA

1.Dökmeci G, Taban K, Süntar İ, Tugay O, Özçelik B. Evaluation of antimicrobial and antibiofilm activities of some Phytolacca americana L. extracts. J. Res. Pharm. 2026;30(1):51-59. doi:10.12991/jrespharm.1629289

Chicago

Dökmeci, Gülbeyaz, Kevser Taban, İpek Süntar, Osman Tugay, and Berrin Özçelik. 2026. “Evaluation of Antimicrobial and Antibiofilm Activities of Some Phytolacca Americana L. Extracts”. Journal of Research in Pharmacy 30 (1): 51-59. https://doi.org/10.12991/jrespharm.1629289.

EndNote

Dökmeci G, Taban K, Süntar İ, Tugay O, Özçelik B (January 1, 2026) Evaluation of antimicrobial and antibiofilm activities of some Phytolacca americana L. extracts. Journal of Research in Pharmacy 30 1 51–59.

IEEE

[1]G. Dökmeci, K. Taban, İ. Süntar, O. Tugay, and B. Özçelik, “Evaluation of antimicrobial and antibiofilm activities of some Phytolacca americana L. extracts”, J. Res. Pharm., vol. 30, no. 1, pp. 51–59, Jan. 2026, doi: 10.12991/jrespharm.1629289.

ISNAD

Dökmeci, Gülbeyaz - Taban, Kevser - Süntar, İpek - Tugay, Osman - Özçelik, Berrin. “Evaluation of Antimicrobial and Antibiofilm Activities of Some Phytolacca Americana L. Extracts”. Journal of Research in Pharmacy 30/1 (January 1, 2026): 51-59. https://doi.org/10.12991/jrespharm.1629289.

JAMA

1.Dökmeci G, Taban K, Süntar İ, Tugay O, Özçelik B. Evaluation of antimicrobial and antibiofilm activities of some Phytolacca americana L. extracts. J. Res. Pharm. 2026;30:51–59.

MLA

Dökmeci, Gülbeyaz, et al. “Evaluation of Antimicrobial and Antibiofilm Activities of Some Phytolacca Americana L. Extracts”. Journal of Research in Pharmacy, vol. 30, no. 1, Jan. 2026, pp. 51-59, doi:10.12991/jrespharm.1629289.

Vancouver

1.Gülbeyaz Dökmeci, Kevser Taban, İpek Süntar, Osman Tugay, Berrin Özçelik. Evaluation of antimicrobial and antibiofilm activities of some Phytolacca americana L. extracts. J. Res. Pharm. 2026 Jan. 1;30(1):51-9. doi:10.12991/jrespharm.1629289