Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus

Turgut Taşkın; Muhammet Emin Çam; Gizem Emre; Ayşe Nur Hazar-yavuz; Levent Kabasakal; Leyla Bitiş

Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus

Abstract

The purpose of this study was to comparatively reveal for the first time the antioxidant, anti-inflammatory effects of Phlomis pungens and Coridothymus capitatus methanol extracts obtained by using maceration extraction method. According to the results of anti-inflammatory activity, P. pungens methanolic extract demonstrated a more prominent and intensive antiinflammatory effect with 24.7% of inhibitive capacity in the altered edema size after the first hour of carrageenan injection compared to C. capitatus methanolic extract. P. pungens methanolic extract inhibitory effect increased during three hours and reached maximum by 41.9%. According to the results obtained from antioxidant activity experiments, methanol extract of C. capitatus exhibited stronger free radical scavenging (DPPH), cupric reducing (CUPRAC), ferric reducing/antioxidant power (FRAP) and ABTS radical cation scavenging activity than P. pungens extract. In additon, C. capitatus extract had higher ABTS radical cation scavenging and ferric reducing/antioxidant power activity than ascorbic acid, BHT and BHA, respectively. Therefore, this extract can be used in both medicine and food industry as a natural antioxidant source.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy, Pharmaceutical Botany

Journal Section

Research Article

Authors

Turgut Taşkın ^*
0000-0001-8475-6478
Türkiye

Muhammet Emin Çam
0000-0001-5398-6801
Türkiye

Gizem Emre
0000-0003-3996-0116
Türkiye

Ayşe Nur Hazar-yavuz
0000-0003-0784-8779
Türkiye

Levent Kabasakal
0000-0002-5474-6436
Türkiye

Leyla Bitiş
0000-0003-1167-6666
Türkiye

Publication Date

June 27, 2025

Submission Date

July 14, 2017

Acceptance Date

September 9, 2017

Published in Issue

Year 2018 Volume: 22 Number: 1

IZ

https://izlik.org/JA64BE34WK

Cite

RIS / Bibtex

APA

Taşkın, T., Çam, M. E., Emre, G., Hazar-yavuz, A. N., Kabasakal, L., & Bitiş, L. (2025). Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus. Journal of Research in Pharmacy, 22(1), 80-85. https://izlik.org/JA64BE34WK

AMA

1.Taşkın T, Çam ME, Emre G, Hazar-yavuz AN, Kabasakal L, Bitiş L. Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus. J. Res. Pharm. 2025;22(1):80-85. https://izlik.org/JA64BE34WK

Chicago

Taşkın, Turgut, Muhammet Emin Çam, Gizem Emre, Ayşe Nur Hazar-yavuz, Levent Kabasakal, and Leyla Bitiş. 2025. “Antioxidant and Anti-Inflammatory Activities of Phlomis Pungens and Coridothymus Capitatus”. Journal of Research in Pharmacy 22 (1): 80-85. https://izlik.org/JA64BE34WK.

EndNote

Taşkın T, Çam ME, Emre G, Hazar-yavuz AN, Kabasakal L, Bitiş L (June 1, 2025) Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus. Journal of Research in Pharmacy 22 1 80–85.

IEEE

[1]T. Taşkın, M. E. Çam, G. Emre, A. N. Hazar-yavuz, L. Kabasakal, and L. Bitiş, “Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus”, J. Res. Pharm., vol. 22, no. 1, pp. 80–85, June 2025, [Online]. Available: https://izlik.org/JA64BE34WK

ISNAD

Taşkın, Turgut - Çam, Muhammet Emin - Emre, Gizem - Hazar-yavuz, Ayşe Nur - Kabasakal, Levent - Bitiş, Leyla. “Antioxidant and Anti-Inflammatory Activities of Phlomis Pungens and Coridothymus Capitatus”. Journal of Research in Pharmacy 22/1 (June 1, 2025): 80-85. https://izlik.org/JA64BE34WK.

JAMA

1.Taşkın T, Çam ME, Emre G, Hazar-yavuz AN, Kabasakal L, Bitiş L. Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus. J. Res. Pharm. 2025;22:80–85.

MLA

Taşkın, Turgut, et al. “Antioxidant and Anti-Inflammatory Activities of Phlomis Pungens and Coridothymus Capitatus”. Journal of Research in Pharmacy, vol. 22, no. 1, June 2025, pp. 80-85, https://izlik.org/JA64BE34WK.

Vancouver

1.Turgut Taşkın, Muhammet Emin Çam, Gizem Emre, Ayşe Nur Hazar-yavuz, Levent Kabasakal, Leyla Bitiş. Antioxidant and anti-inflammatory activities of Phlomis pungens and Coridothymus capitatus. J. Res. Pharm. [Internet]. 2025 Jun. 1;22(1):80-5. Available from: https://izlik.org/JA64BE34WK