Evaluation of anti-lipase activity of leaf and bark extracts from Aquilaria subintegra and A. malaccensis

Maustra İbrahim; Saripah Salbiah Syed Abdul Azziz; Chee Fah Wong; Wan Nor Izzati Wan Mohamad Din; Wan Rusmawati Wan Mahamod; Yuhanid Mhd Bakri; Mohamad Syahrizal Ahmad; Rozita Yahaya; Nor Hadiani Ismail; Wan Mohd Nuzul Hakimi Wan Salleh

Evaluation of anti-lipase activity of leaf and bark extracts from Aquilaria subintegra and A. malaccensis

Abstract

Obesity is one of the serious health condition in the world and contributes to many chronic illnesses augmenting to high risk of death rate. With the purpose of obesity treatment, natural sources come to be significant to replace commercial drugs due to their harmful effect to the body. Therefore, a lot of studies were conducted on natural sources due to their potential as medicinal herbs. Aquilaria sp. plants are well known in traditional medicine as a sedative, analgesic and digestive. Even though there were no reports on applications of Aquilaria sp. towards obesity treatment, this plant has traditionally been used as laxative for weight reducing. In this study, the anti-lipase activity of an extract of barks and leaves from A. subintegra and A. malaccensis were investigated. The anti-lipase activity was measured by colorimetric assay on pancreatic lipase activity using porcine pancreatic lipase (PPL; triacylglycerol lipase, EC 3.1.1.3). The result indicated that among these two species of Aquilaria, A. malaccensis bark in dichloromethane crude showed high anti-lipase activity. Thus, these results suggest that Aquilaria sp. plant extracts might be of therapeutic interest with respect to the treatment

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Research Article

Authors

Maustra İbrahim ^* This is me
0000-0003-0668-3909
Malaysia

Saripah Salbiah Syed Abdul Azziz This is me
0000-0002-8499-3745
Malaysia

Chee Fah Wong This is me
0000-0003-1114-7000
Malaysia

Wan Nor Izzati Wan Mohamad Din This is me
Malaysia

Wan Rusmawati Wan Mahamod This is me
0000-0003-1885-1893
Malaysia

Yuhanid Mhd Bakri This is me
0000-0003-4780-9897
Malaysia

Mohamad Syahrizal Ahmad This is me
0000-0002-9278-6332
Malaysia

Rozita Yahaya This is me
0000-0002-1325-8751
Malaysia

Nor Hadiani Ismail This is me
0000-0002-2374-4630
Malaysia

Wan Mohd Nuzul Hakimi Wan Salleh
0000-0003-1408-229X
Malaysia

Publication Date

June 27, 2025

Submission Date

May 30, 2017

Acceptance Date

September 15, 2017

Published in Issue

Year 2018 Volume: 22 Number: 1

IZ

https://izlik.org/JA58AA87GP

Cite

RIS / Bibtex

APA

İbrahim, M., Syed Abdul Azziz, S. S., Wong, C. F., Wan Mohamad Din, W. N. I., Wan Mahamod, W. R., Bakri, Y. M., Ahmad, M. S., Yahaya, R., Ismail, N. H., & Salleh, W. M. N. H. W. (2025). Evaluation of anti-lipase activity of leaf and bark extracts from Aquilaria subintegra and A. malaccensis. Journal of Research in Pharmacy, 22(1), 91-95. https://izlik.org/JA58AA87GP

AMA

1.İbrahim M, Syed Abdul Azziz SS, Wong CF, et al. Evaluation of anti-lipase activity of leaf and bark extracts from Aquilaria subintegra and A. malaccensis. J. Res. Pharm. 2025;22(1):91-95. https://izlik.org/JA58AA87GP

Chicago

İbrahim, Maustra, Saripah Salbiah Syed Abdul Azziz, Chee Fah Wong, et al. 2025. “Evaluation of Anti-Lipase Activity of Leaf and Bark Extracts from Aquilaria Subintegra and A. Malaccensis”. Journal of Research in Pharmacy 22 (1): 91-95. https://izlik.org/JA58AA87GP.

EndNote

İbrahim M, Syed Abdul Azziz SS, Wong CF, Wan Mohamad Din WNI, Wan Mahamod WR, Bakri YM, Ahmad MS, Yahaya R, Ismail NH, Salleh WMNHW (June 1, 2025) Evaluation of anti-lipase activity of leaf and bark extracts from Aquilaria subintegra and A. malaccensis. Journal of Research in Pharmacy 22 1 91–95.

IEEE

[1]M. İbrahim et al., “Evaluation of anti-lipase activity of leaf and bark extracts from Aquilaria subintegra and A. malaccensis”, J. Res. Pharm., vol. 22, no. 1, pp. 91–95, June 2025, [Online]. Available: https://izlik.org/JA58AA87GP

ISNAD

İbrahim, Maustra - Syed Abdul Azziz, Saripah Salbiah - Wong, Chee Fah - Wan Mohamad Din, Wan Nor Izzati - Wan Mahamod, Wan Rusmawati - Bakri, Yuhanid Mhd - Ahmad, Mohamad Syahrizal - Yahaya, Rozita - Ismail, Nor Hadiani - Salleh, Wan Mohd Nuzul Hakimi Wan. “Evaluation of Anti-Lipase Activity of Leaf and Bark Extracts from Aquilaria Subintegra and A. Malaccensis”. Journal of Research in Pharmacy 22/1 (June 1, 2025): 91-95. https://izlik.org/JA58AA87GP.

JAMA

1.İbrahim M, Syed Abdul Azziz SS, Wong CF, Wan Mohamad Din WNI, Wan Mahamod WR, Bakri YM, Ahmad MS, Yahaya R, Ismail NH, Salleh WMNHW. Evaluation of anti-lipase activity of leaf and bark extracts from Aquilaria subintegra and A. malaccensis. J. Res. Pharm. 2025;22:91–95.

MLA

İbrahim, Maustra, et al. “Evaluation of Anti-Lipase Activity of Leaf and Bark Extracts from Aquilaria Subintegra and A. Malaccensis”. Journal of Research in Pharmacy, vol. 22, no. 1, June 2025, pp. 91-95, https://izlik.org/JA58AA87GP.

Vancouver

1.Maustra İbrahim, Saripah Salbiah Syed Abdul Azziz, Chee Fah Wong, Wan Nor Izzati Wan Mohamad Din, Wan Rusmawati Wan Mahamod, Yuhanid Mhd Bakri, Mohamad Syahrizal Ahmad, Rozita Yahaya, Nor Hadiani Ismail, Wan Mohd Nuzul Hakimi Wan Salleh. Evaluation of anti-lipase activity of leaf and bark extracts from Aquilaria subintegra and A. malaccensis. J. Res. Pharm. [Internet]. 2025 Jun. 1;22(1):91-5. Available from: https://izlik.org/JA58AA87GP