Research Article

Chemical composition and larvicidal activity of essential oils from Nepeta cadmea Boiss. and Pimpinella anisum L. on the larvae of Culex pipiens L.

Volume: 22 Number: 2 June 27, 2025

Chemical composition and larvicidal activity of essential oils from Nepeta cadmea Boiss. and Pimpinella anisum L. on the larvae of Culex pipiens L.

Abstract

Culex pipiens L. (Diptera: Culicidae) is an important vector of West Nile virus in many parts of the world. In this research, the essential oils obtained from Nepeta cadmea Boiss. (endemic for Turkey) and Pimpinella anisum L. were examined for larvicidal activity against second-third instar larvae of Cx. pipiens. The essential oils were distilled from aerial parts of N. cadmea and seeds of P. anisum by water distillation. The chemical composition of these oils was determined by gas chromatography-mass spectrometry (GC-MS). The lethal concentration 50 and 90 values of these essential oils were 28.7 and 49.51 ppm, and 39.82 and 74.57 ppm, respectively. As a result, both essential oils were found highly toxic to larvae of Cx. pipiens. Our results showed that the essential oils obtained from N. cadmea and P. anisum may be suitable for the development of potential new botanical insecticides.

Keywords

References

  1. [1] Benelli G, Mehlhorn H. Declining malaria, rising of dengue and Zika virus: insights for mosquito vector control. Parasitol Res. 2016;115(5):1747–1754.
  2. [2] Li XF, Han JF, Shi PY, Qin CF. Zika virus: a new threat from mosquitoes. Sci China Life Sci. 2016;59(4):440–442.
  3. [3] Ramsdale CD, Alten B, Caglar SS, Ozer N. A revised, annotated checklist of the mosquitoes [Diptera, Culicidae] of Turkey. Eur Mosq Bull. 2001;9:18-28.
  4. [4] Günay F, Alten B, Simsek F, Aldemir A, Linton YM. Barcoding Turkish Culex mosquitoes to facilitate arbovirus vector incrimination studies reveals hidden diversity and new potential vectors. Acta Trop. 2015;143:112–120.
  5. [5] Cetin H, Yanikoglu A. Mosquito (Diptera: Culicidae) species, their breeding sites and some biological aspects of dominant species Culex pipiens L. in Antalya, Turkey. Turkish J Entomol. Derg. 2004;28(4):283-294.
  6. [6] Andreadis TG, Armstrong PM, Bajwa WI. Studies on hibernating populations of Culex pipiens from a West Nile virus endemic focus in New York City: Parity rates and isolation of West Nile virus. J Am Mosq Control Assoc. 2010;26:257-264.
  7. [7] Rose RI. Pesticides and public health: integrated methods of mosquito management. Emerg Infect Dis. 2001;7(1):17-23.
  8. [8] Wirth MC. Mosquito resistance to bacterial larvicidal toxins. Open Toxicol J. 2010;3:126–140.

Details

Primary Language

English

Subjects

Pharmacy Management

Journal Section

Research Article

Publication Date

June 27, 2025

Submission Date

October 20, 2017

Acceptance Date

December 21, 2017

Published in Issue

Year 2018 Volume: 22 Number: 2

APA
Öz, E., Koç, S., Çinbilgel, İ., Yanıkoğlu, A., & Çetin, H. (2025). Chemical composition and larvicidal activity of essential oils from Nepeta cadmea Boiss. and Pimpinella anisum L. on the larvae of Culex pipiens L. Journal of Research in Pharmacy, 22(2), 322-327. https://izlik.org/JA34HN86WW
AMA
1.Öz E, Koç S, Çinbilgel İ, Yanıkoğlu A, Çetin H. Chemical composition and larvicidal activity of essential oils from Nepeta cadmea Boiss. and Pimpinella anisum L. on the larvae of Culex pipiens L. J. Res. Pharm. 2025;22(2):322-327. https://izlik.org/JA34HN86WW
Chicago
Öz, Emre, Samed Koç, İlker Çinbilgel, Atila Yanıkoğlu, and Hüseyin Çetin. 2025. “Chemical Composition and Larvicidal Activity of Essential Oils from Nepeta Cadmea Boiss. and Pimpinella Anisum L. On the Larvae of Culex Pipiens L”. Journal of Research in Pharmacy 22 (2): 322-27. https://izlik.org/JA34HN86WW.
EndNote
Öz E, Koç S, Çinbilgel İ, Yanıkoğlu A, Çetin H (June 1, 2025) Chemical composition and larvicidal activity of essential oils from Nepeta cadmea Boiss. and Pimpinella anisum L. on the larvae of Culex pipiens L. Journal of Research in Pharmacy 22 2 322–327.
IEEE
[1]E. Öz, S. Koç, İ. Çinbilgel, A. Yanıkoğlu, and H. Çetin, “Chemical composition and larvicidal activity of essential oils from Nepeta cadmea Boiss. and Pimpinella anisum L. on the larvae of Culex pipiens L”., J. Res. Pharm., vol. 22, no. 2, pp. 322–327, June 2025, [Online]. Available: https://izlik.org/JA34HN86WW
ISNAD
Öz, Emre - Koç, Samed - Çinbilgel, İlker - Yanıkoğlu, Atila - Çetin, Hüseyin. “Chemical Composition and Larvicidal Activity of Essential Oils from Nepeta Cadmea Boiss. and Pimpinella Anisum L. On the Larvae of Culex Pipiens L”. Journal of Research in Pharmacy 22/2 (June 1, 2025): 322-327. https://izlik.org/JA34HN86WW.
JAMA
1.Öz E, Koç S, Çinbilgel İ, Yanıkoğlu A, Çetin H. Chemical composition and larvicidal activity of essential oils from Nepeta cadmea Boiss. and Pimpinella anisum L. on the larvae of Culex pipiens L. J. Res. Pharm. 2025;22:322–327.
MLA
Öz, Emre, et al. “Chemical Composition and Larvicidal Activity of Essential Oils from Nepeta Cadmea Boiss. and Pimpinella Anisum L. On the Larvae of Culex Pipiens L”. Journal of Research in Pharmacy, vol. 22, no. 2, June 2025, pp. 322-7, https://izlik.org/JA34HN86WW.
Vancouver
1.Emre Öz, Samed Koç, İlker Çinbilgel, Atila Yanıkoğlu, Hüseyin Çetin. Chemical composition and larvicidal activity of essential oils from Nepeta cadmea Boiss. and Pimpinella anisum L. on the larvae of Culex pipiens L. J. Res. Pharm. [Internet]. 2025 Jun. 1;22(2):322-7. Available from: https://izlik.org/JA34HN86WW