Investigation of vehicle-induced whole-body vibration with experimental rat models

Ayşe Nur Hazar-yavuz; Akif Yavuz

doi:10.29228/jrp.519

Investigation of vehicle-induced whole-body vibration with experimental rat models

Abstract

This comprehensive study delves into the profound impact of low frequency whole-body vibrations (WBV) on health, focusing on the utilization of rat models for understanding this complex phenomenon. It highlights the adverse effects of low frequency vehicle vibrations on human health, encompassing musculoskeletal discomfort, fatigue, concentration deficits, potential gastrointestinal issues, hearing impairment, and psychological stress. WBV's influence extends to physiological and cognitive consequences, affecting multiple systems. Prolonged WBV exposure, particularly in the lumbar region, is associated with spinal disorders. To navigate ethical challenges in studying WBV in humans, rat models are crucial tools. These models, with customized parameters, offer insights into various health aspects, including bone density, muscle strength, hormonal responses, cardiovascular parameters, and more. Advantages and disadvantages of using low-frequency vibrations in rat models are discussed. While demonstrating WBV's potential effect in research, further exploration is essential to optimize parameters and applications, always prioritizing ethical considerations and regulations. The article concludes by proposing measures to mitigate vehicle vibration impacts on drivers, emphasizing the collaboration of manufacturers, drivers, and regulators for safer and healthier driving experiences.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacology and Pharmaceutical Sciences (Other)

Journal Section

Review

Authors

Ayşe Nur Hazar-yavuz ^*
0000-0003-0784-8779
Türkiye

Akif Yavuz
0000-0002-9447-7306
Türkiye

Publication Date

June 28, 2025

Submission Date

November 4, 2023

Acceptance Date

November 18, 2023

Published in Issue

Year 2023 Volume: 27 Number: 6

DOI

https://doi.org/10.29228/jrp.519

IZ

https://izlik.org/JA56FU57KJ

Cite

RIS / Bibtex

APA

Hazar-yavuz, A. N., & Yavuz, A. (2025). Investigation of vehicle-induced whole-body vibration with experimental rat models. Journal of Research in Pharmacy, 27(6), 2310-2329. https://doi.org/10.29228/jrp.519

AMA

1.Hazar-yavuz AN, Yavuz A. Investigation of vehicle-induced whole-body vibration with experimental rat models. J. Res. Pharm. 2025;27(6):2310-2329. doi:10.29228/jrp.519

Chicago

Hazar-yavuz, Ayşe Nur, and Akif Yavuz. 2025. “Investigation of Vehicle-Induced Whole-Body Vibration With Experimental Rat Models”. Journal of Research in Pharmacy 27 (6): 2310-29. https://doi.org/10.29228/jrp.519.

EndNote

Hazar-yavuz AN, Yavuz A (July 1, 2025) Investigation of vehicle-induced whole-body vibration with experimental rat models. Journal of Research in Pharmacy 27 6 2310–2329.

IEEE

[1]A. N. Hazar-yavuz and A. Yavuz, “Investigation of vehicle-induced whole-body vibration with experimental rat models”, J. Res. Pharm., vol. 27, no. 6, pp. 2310–2329, July 2025, doi: 10.29228/jrp.519.

ISNAD

Hazar-yavuz, Ayşe Nur - Yavuz, Akif. “Investigation of Vehicle-Induced Whole-Body Vibration With Experimental Rat Models”. Journal of Research in Pharmacy 27/6 (July 1, 2025): 2310-2329. https://doi.org/10.29228/jrp.519.

JAMA

1.Hazar-yavuz AN, Yavuz A. Investigation of vehicle-induced whole-body vibration with experimental rat models. J. Res. Pharm. 2025;27:2310–2329.

MLA

Hazar-yavuz, Ayşe Nur, and Akif Yavuz. “Investigation of Vehicle-Induced Whole-Body Vibration With Experimental Rat Models”. Journal of Research in Pharmacy, vol. 27, no. 6, July 2025, pp. 2310-29, doi:10.29228/jrp.519.

Vancouver

1.Ayşe Nur Hazar-yavuz, Akif Yavuz. Investigation of vehicle-induced whole-body vibration with experimental rat models. J. Res. Pharm. 2025 Jul. 1;27(6):2310-29. doi:10.29228/jrp.519