Biological activities of three Phlomis species

Nuraniye Eruygur; Damla Kırcı; Fatma Ayaz; Süleyman Doğu; Yavuz Bağcı

Biological activities of three Phlomis species

Abstract

The genus Phlomis, which belongs to the Lamiaceae family, comprises 100 species native to Turkey, Asia, Europe, and North Africa. As reported in many studies, Phlomis genus has unique therapeutic and aromatic properties. According to the data obtained from traditional uses, Phlomis species have a characteristic taste and so are traditionally consumed as herbal tea to treat diabetes, gastrointestinal disease as well as maintain overall health by protecting the liver, kidney, bone, and cardiovascular systems. In this present work, it was focused on the evaluation of the in-vitro enzyme inhibition (α-glucosidase, α-amylase, acetylcholinesterase (AChE)/butyrylcholinesterase (BuChE), and tyrosinase (TYR) and non-enzyme antioxidant activities (TPC, TFC, DPPH, and ABTS radical scavenging assays, and Iron-chelating activity assay) of the dichloromethane (DCM) and methanol extracts prepared from aerial parts of Phlomis nissolii, P. samia and P. sieheana with ultrasonic assisted method. All methanol extracts were rich in phenolic compounds and have high antioxidant activities. In the literature, there is no activity study related to the extracts of P. sieheana. The methanol extract of P. samia was the most active among other observed species. Especially the high tyrosinase enzyme inhibition activity of P. sieheana DCM extract may be promising for cosmetic product development.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Research Article

Authors

Nuraniye Eruygur ^*
Türkiye

Damla Kırcı
0000-0002-3479-3999
Türkiye

Fatma Ayaz
Türkiye

Süleyman Doğu
0000-0002-5352-9288
Türkiye

Yavuz Bağcı
Türkiye

Publication Date

June 28, 2025

Submission Date

July 7, 2021

Acceptance Date

December 14, 2021

Published in Issue

Year 2022 Volume: 26 Number: 2

IZ

https://izlik.org/JA52SB64BW

Cite

RIS / Bibtex

APA

Eruygur, N., Kırcı, D., Ayaz, F., Doğu, S., & Bağcı, Y. (2025). Biological activities of three Phlomis species. Journal of Research in Pharmacy, 26(2), 255-262. https://izlik.org/JA52SB64BW

AMA

1.Eruygur N, Kırcı D, Ayaz F, Doğu S, Bağcı Y. Biological activities of three Phlomis species. J. Res. Pharm. 2025;26(2):255-262. https://izlik.org/JA52SB64BW

Chicago

Eruygur, Nuraniye, Damla Kırcı, Fatma Ayaz, Süleyman Doğu, and Yavuz Bağcı. 2025. “Biological Activities of Three Phlomis Species”. Journal of Research in Pharmacy 26 (2): 255-62. https://izlik.org/JA52SB64BW.

EndNote

Eruygur N, Kırcı D, Ayaz F, Doğu S, Bağcı Y (June 1, 2025) Biological activities of three Phlomis species. Journal of Research in Pharmacy 26 2 255–262.

IEEE

[1]N. Eruygur, D. Kırcı, F. Ayaz, S. Doğu, and Y. Bağcı, “Biological activities of three Phlomis species”, J. Res. Pharm., vol. 26, no. 2, pp. 255–262, June 2025, [Online]. Available: https://izlik.org/JA52SB64BW

ISNAD

Eruygur, Nuraniye - Kırcı, Damla - Ayaz, Fatma - Doğu, Süleyman - Bağcı, Yavuz. “Biological Activities of Three Phlomis Species”. Journal of Research in Pharmacy 26/2 (June 1, 2025): 255-262. https://izlik.org/JA52SB64BW.

JAMA

1.Eruygur N, Kırcı D, Ayaz F, Doğu S, Bağcı Y. Biological activities of three Phlomis species. J. Res. Pharm. 2025;26:255–262.

MLA

Eruygur, Nuraniye, et al. “Biological Activities of Three Phlomis Species”. Journal of Research in Pharmacy, vol. 26, no. 2, June 2025, pp. 255-62, https://izlik.org/JA52SB64BW.

Vancouver

1.Nuraniye Eruygur, Damla Kırcı, Fatma Ayaz, Süleyman Doğu, Yavuz Bağcı. Biological activities of three Phlomis species. J. Res. Pharm. [Internet]. 2025 Jun. 1;26(2):255-62. Available from: https://izlik.org/JA52SB64BW