Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities

Nurdan Kekeç; Turgut Taşkın; Dicle Naz Ağar; Berna Özbek Çelik; Şükran Kültür; Sevda Süzgeç Selçuk

Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities

Abstract

Helichrysum armenium subsp. armenium plant was extracted with the Soxhlet apparatus. The obtained extract was fractionated and, respectively, AHB (petroleum ether–60% ethanol-chloroform), AHC (ethanol-toluene), AHD (ethanol-chloroform), and AHE (ethanol-ethylacetate) extracts were obtained. Then, antimicrobial, antioxidant, and acetylcholinesterase activity studies were performed on these extracts. In this study, with the using the LC-HRMS method from the aerial parts of Helichrysum armenium subsp. armenium, the flavonoids: apigenin, apigenin 7-glucoside, apigenin 7-methylate, luteolin 7-glucoside, kaempferol, quercetin, quercitrin, (+)-trans taxifolin, (-)-epicatechin gallate, sinensetin, rutin, 3'-o-methyl quercetin, hispidulin, chrysin, acacetin, genkwanin, chrysoeriol; the phenolic acids: chlorogenic acid, ascorbic acid, fumaric acid, caffeic acid, salicylic acid, caffeic acid phenethyl ester, emodin, vanilic acid; the alkaloid: caffeine and the saponoside; glycyrrhizic acid were obtained.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Research Article

Authors

Nurdan Kekeç This is me
0009-0007-9997-0267
Türkiye

Turgut Taşkın
0000-0001-8475-6478
Türkiye

Dicle Naz Ağar
0000-0002-8165-8618
Türkiye

Berna Özbek Çelik
0000-0001-8909-8398
Türkiye

Şükran Kültür
0000-0001-9413-5210
Türkiye

Sevda Süzgeç Selçuk ^*
0000-0002-1552-7521
Türkiye

Publication Date

June 28, 2025

Submission Date

December 22, 2023

Acceptance Date

April 5, 2024

Published in Issue

Year 2024 Volume: 28 Number: 3

IZ

https://izlik.org/JA39GJ64SY

Cite

RIS / Bibtex

APA

Kekeç, N., Taşkın, T., Ağar, D. N., Özbek Çelik, B., Kültür, Ş., & Süzgeç Selçuk, S. (2025). Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities. Journal of Research in Pharmacy, 28(3), 630-640. https://izlik.org/JA39GJ64SY

AMA

1.Kekeç N, Taşkın T, Ağar DN, Özbek Çelik B, Kültür Ş, Süzgeç Selçuk S. Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities. J. Res. Pharm. 2025;28(3):630-640. https://izlik.org/JA39GJ64SY

Chicago

Kekeç, Nurdan, Turgut Taşkın, Dicle Naz Ağar, Berna Özbek Çelik, Şükran Kültür, and Sevda Süzgeç Selçuk. 2025. “Phytochemical Studies of Helichrysum Armenium Subsp. Armenium and Its Antioxidant, Acetylcholinesterase, and Antimicrobial Activities”. Journal of Research in Pharmacy 28 (3): 630-40. https://izlik.org/JA39GJ64SY.

EndNote

Kekeç N, Taşkın T, Ağar DN, Özbek Çelik B, Kültür Ş, Süzgeç Selçuk S (June 1, 2025) Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities. Journal of Research in Pharmacy 28 3 630–640.

IEEE

[1]N. Kekeç, T. Taşkın, D. N. Ağar, B. Özbek Çelik, Ş. Kültür, and S. Süzgeç Selçuk, “Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities”, J. Res. Pharm., vol. 28, no. 3, pp. 630–640, June 2025, [Online]. Available: https://izlik.org/JA39GJ64SY

ISNAD

Kekeç, Nurdan - Taşkın, Turgut - Ağar, Dicle Naz - Özbek Çelik, Berna - Kültür, Şükran - Süzgeç Selçuk, Sevda. “Phytochemical Studies of Helichrysum Armenium Subsp. Armenium and Its Antioxidant, Acetylcholinesterase, and Antimicrobial Activities”. Journal of Research in Pharmacy 28/3 (June 1, 2025): 630-640. https://izlik.org/JA39GJ64SY.

JAMA

1.Kekeç N, Taşkın T, Ağar DN, Özbek Çelik B, Kültür Ş, Süzgeç Selçuk S. Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities. J. Res. Pharm. 2025;28:630–640.

MLA

Kekeç, Nurdan, et al. “Phytochemical Studies of Helichrysum Armenium Subsp. Armenium and Its Antioxidant, Acetylcholinesterase, and Antimicrobial Activities”. Journal of Research in Pharmacy, vol. 28, no. 3, June 2025, pp. 630-4, https://izlik.org/JA39GJ64SY.

Vancouver

1.Nurdan Kekeç, Turgut Taşkın, Dicle Naz Ağar, Berna Özbek Çelik, Şükran Kültür, Sevda Süzgeç Selçuk. Phytochemical studies of Helichrysum armenium subsp. armenium and its antioxidant, acetylcholinesterase, and antimicrobial activities. J. Res. Pharm. [Internet]. 2025 Jun. 1;28(3):630-4. Available from: https://izlik.org/JA39GJ64SY