Chemical composition of essential oil / volatiles and fatty acids, and antimicrobial evaluation of two endemic Achillea (Asteraceae) species: Achillea schischkinii Sosn. and Achillea teretifolia Willd.

Gamze Göger; Melisa Ergül Görel; Yasin Burak Birtek; Mehmet Tekin; Gülmira Özek

Chemical composition of essential oil / volatiles and fatty acids, and antimicrobial evaluation of two endemic Achillea (Asteraceae) species: Achillea schischkinii Sosn. and Achillea teretifolia Willd.

Abstract

In the present study, phytochemical analyzes and investigations for in vitro antimicrobial activity of two endemic species Achillea schischkinii Sosn. and A. teretifolia Willd. were carried out. The essential oils and fatty acids as well as the different solvents extracts were obtained from aerial parts of the plants. Gas chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC / MS) techniques were used to analyze the phytochemical composition of the volatiles and fatty acid methyl esters. In vitro antimicrobial evaluations of the plant extracts were determined against Escherichia coli ATCC 8739, Staphylococcus aureus ATCC 6538, Candida albicans ATCC 10231, C. parapsilosis ATCC 22019, C. tropicalis ATCC 750, and C. glabrata ATCC 90030 by microdilution method. The antifungal combination of infusion of A. schischkinii with fluconazole was determined by the checkerboard method againts Candida species. Chemical compositions of A. schischkinii and A. teretifolia were determined as 1,8-cineol (25.2-30.4 %), and camphor (7.0-5.5 %). Antimicrobial evaluation of different extracts of A. teretifolia, were performed for the first time in this study. The MIC values were observed between at 156.25-5000 µg / mL for both of the plant extracts. The combination showed a synergistic effect (FIC ≤0.5) against C. albicans and C. parapsilosis.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Research Article

Authors

Gamze Göger ^*
0000-0003-2978-5385
Türkiye

Melisa Ergül Görel
0000-0002-3659-503X
Türkiye

Yasin Burak Birtek This is me
0009-0006-0502-6519
Türkiye

Mehmet Tekin
0000-0002-6504-2223
Türkiye

Gülmira Özek
0000-0001-8908-6098
Türkiye

Publication Date

June 28, 2025

Submission Date

July 17, 2023

Acceptance Date

September 10, 2023

Published in Issue

Year 2024 Volume: 28 Number: 3

IZ

https://izlik.org/JA89EM77AD

Cite

RIS / Bibtex

APA

Göger, G., Görel, M. E., Birtek, Y. B., Tekin, M., & Özek, G. (2025). Chemical composition of essential oil / volatiles and fatty acids, and antimicrobial evaluation of two endemic Achillea (Asteraceae) species: Achillea schischkinii Sosn. and Achillea teretifolia Willd. Journal of Research in Pharmacy, 28(3), 679-690. https://izlik.org/JA89EM77AD

AMA

1.Göger G, Görel ME, Birtek YB, Tekin M, Özek G. Chemical composition of essential oil / volatiles and fatty acids, and antimicrobial evaluation of two endemic Achillea (Asteraceae) species: Achillea schischkinii Sosn. and Achillea teretifolia Willd. J. Res. Pharm. 2025;28(3):679-690. https://izlik.org/JA89EM77AD

Chicago

Göger, Gamze, Melisa Ergül Görel, Yasin Burak Birtek, Mehmet Tekin, and Gülmira Özek. 2025. “Chemical Composition of Essential Oil Volatiles and Fatty Acids, and Antimicrobial Evaluation of Two Endemic Achillea (Asteraceae) Species: Achillea Schischkinii Sosn. And Achillea Teretifolia Willd”. Journal of Research in Pharmacy 28 (3): 679-90. https://izlik.org/JA89EM77AD.

EndNote

Göger G, Görel ME, Birtek YB, Tekin M, Özek G (June 1, 2025) Chemical composition of essential oil / volatiles and fatty acids, and antimicrobial evaluation of two endemic Achillea (Asteraceae) species: Achillea schischkinii Sosn. and Achillea teretifolia Willd. Journal of Research in Pharmacy 28 3 679–690.

IEEE

[1]G. Göger, M. E. Görel, Y. B. Birtek, M. Tekin, and G. Özek, “Chemical composition of essential oil / volatiles and fatty acids, and antimicrobial evaluation of two endemic Achillea (Asteraceae) species: Achillea schischkinii Sosn. and Achillea teretifolia Willd”., J. Res. Pharm., vol. 28, no. 3, pp. 679–690, June 2025, [Online]. Available: https://izlik.org/JA89EM77AD

ISNAD

Göger, Gamze - Görel, Melisa Ergül - Birtek, Yasin Burak - Tekin, Mehmet - Özek, Gülmira. “Chemical Composition of Essential Oil Volatiles and Fatty Acids, and Antimicrobial Evaluation of Two Endemic Achillea (Asteraceae) Species: Achillea Schischkinii Sosn. And Achillea Teretifolia Willd”. Journal of Research in Pharmacy 28/3 (June 1, 2025): 679-690. https://izlik.org/JA89EM77AD.

JAMA

1.Göger G, Görel ME, Birtek YB, Tekin M, Özek G. Chemical composition of essential oil / volatiles and fatty acids, and antimicrobial evaluation of two endemic Achillea (Asteraceae) species: Achillea schischkinii Sosn. and Achillea teretifolia Willd. J. Res. Pharm. 2025;28:679–690.

MLA

Göger, Gamze, et al. “Chemical Composition of Essential Oil Volatiles and Fatty Acids, and Antimicrobial Evaluation of Two Endemic Achillea (Asteraceae) Species: Achillea Schischkinii Sosn. And Achillea Teretifolia Willd”. Journal of Research in Pharmacy, vol. 28, no. 3, June 2025, pp. 679-90, https://izlik.org/JA89EM77AD.

Vancouver

1.Gamze Göger, Melisa Ergül Görel, Yasin Burak Birtek, Mehmet Tekin, Gülmira Özek. Chemical composition of essential oil / volatiles and fatty acids, and antimicrobial evaluation of two endemic Achillea (Asteraceae) species: Achillea schischkinii Sosn. and Achillea teretifolia Willd. J. Res. Pharm. [Internet]. 2025 Jun. 1;28(3):679-90. Available from: https://izlik.org/JA89EM77AD