Synthesis and antimicrobial effects of cyclotriphosphazenes containing monocarbonyl curcumin analogs

Mine Gül Şeker; Tuğçe Akbal; Devrim Atilla; Neslihan Avşar; Hanife İbişoğlu

Synthesis and antimicrobial effects of cyclotriphosphazenes containing monocarbonyl curcumin analogs

Abstract

Six novel bridged structure cyclotriphosphazenes (4a-f) were synthesized from the reactions of aryloxycyclotriphosphazenes [aryloxy= phenoxy (2a) and (2-naphthoxy) (2b)] with monocarbonyl curcumin derivatives [acetone (3a), cyclopentanone (3b) and cyclohexanone (3c)] for the first time. The structures of the compounds (4a-f) were defined by elemental analysis, FT-IR, mass and NMR (1H and 31P) spectroscopies. The antimicrobial properties of the compounds (2a, 2b, 3a-c and 4a-f) were screened in vitro against Escherichia coli ATCC 8739, Staphylococcus aureus ATCC 29213, Bacillus subtilis ATCC 6633, Bacillus cereus DSMZ 4312 and Candida albicans ATCC 10231. In addition, effective substance of 3b and 4c were evaluated Minimal Inhibition Concentration.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmaceutical Chemistry

Journal Section

Research Article

Authors

Mine Gül Şeker ^* This is me
0009-0007-4176-6191
Türkiye

Tuğçe Akbal This is me
Türkiye

Devrim Atilla
0000-0001-8992-0070
Türkiye

Neslihan Avşar This is me
0000-0002-7315-5674
Türkiye

Hanife İbişoğlu
Türkiye

Publication Date

June 27, 2025

Submission Date

January 8, 2018

Acceptance Date

February 18, 2018

Published in Issue

Year 2018 Volume: 22 Number: 4

IZ

https://izlik.org/JA45LT33ER

Cite

RIS / Bibtex

APA

Gül Şeker, M., Akbal, T., Atilla, D., Avşar, N., & İbişoğlu, H. (2025). Synthesis and antimicrobial effects of cyclotriphosphazenes containing monocarbonyl curcumin analogs. Journal of Research in Pharmacy, 22(4), 536-546. https://izlik.org/JA45LT33ER

AMA

1.Gül Şeker M, Akbal T, Atilla D, Avşar N, İbişoğlu H. Synthesis and antimicrobial effects of cyclotriphosphazenes containing monocarbonyl curcumin analogs. J. Res. Pharm. 2025;22(4):536-546. https://izlik.org/JA45LT33ER

Chicago

Gül Şeker, Mine, Tuğçe Akbal, Devrim Atilla, Neslihan Avşar, and Hanife İbişoğlu. 2025. “Synthesis and Antimicrobial Effects of Cyclotriphosphazenes Containing Monocarbonyl Curcumin Analogs”. Journal of Research in Pharmacy 22 (4): 536-46. https://izlik.org/JA45LT33ER.

EndNote

Gül Şeker M, Akbal T, Atilla D, Avşar N, İbişoğlu H (June 1, 2025) Synthesis and antimicrobial effects of cyclotriphosphazenes containing monocarbonyl curcumin analogs. Journal of Research in Pharmacy 22 4 536–546.

IEEE

[1]M. Gül Şeker, T. Akbal, D. Atilla, N. Avşar, and H. İbişoğlu, “Synthesis and antimicrobial effects of cyclotriphosphazenes containing monocarbonyl curcumin analogs”, J. Res. Pharm., vol. 22, no. 4, pp. 536–546, June 2025, [Online]. Available: https://izlik.org/JA45LT33ER

ISNAD

Gül Şeker, Mine - Akbal, Tuğçe - Atilla, Devrim - Avşar, Neslihan - İbişoğlu, Hanife. “Synthesis and Antimicrobial Effects of Cyclotriphosphazenes Containing Monocarbonyl Curcumin Analogs”. Journal of Research in Pharmacy 22/4 (June 1, 2025): 536-546. https://izlik.org/JA45LT33ER.

JAMA

1.Gül Şeker M, Akbal T, Atilla D, Avşar N, İbişoğlu H. Synthesis and antimicrobial effects of cyclotriphosphazenes containing monocarbonyl curcumin analogs. J. Res. Pharm. 2025;22:536–546.

MLA

Gül Şeker, Mine, et al. “Synthesis and Antimicrobial Effects of Cyclotriphosphazenes Containing Monocarbonyl Curcumin Analogs”. Journal of Research in Pharmacy, vol. 22, no. 4, June 2025, pp. 536-4, https://izlik.org/JA45LT33ER.

Vancouver

1.Mine Gül Şeker, Tuğçe Akbal, Devrim Atilla, Neslihan Avşar, Hanife İbişoğlu. Synthesis and antimicrobial effects of cyclotriphosphazenes containing monocarbonyl curcumin analogs. J. Res. Pharm. [Internet]. 2025 Jun. 1;22(4):536-4. Available from: https://izlik.org/JA45LT33ER