In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein

Halil Aksoy; Turgut Şekerler; Naz Mina Mert

In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein

Abstract

Wound healing is a process that involves biochemical processes such as inflammation and cell proliferation and is controlled by many proteins. It is known that one of the most effective factors in this process is the inhibition of GSK3-β protein. In current study, in silico wound healing activity of the some compounds found in the tubers of Asphodelus species used as a wound healing in traditional medicine were investigated. For this purpose, the interactions between the compounds and GSK3-β protein were studied in silico. As a result of the study, it has been determined that and stigmasterol, β-sitosterol and emodin molecules are effective.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmaceutical Biochemistry

Journal Section

Research Article

Authors

Halil Aksoy ^*
Türkiye

Turgut Şekerler
Türkiye

Naz Mina Mert This is me
Türkiye

Publication Date

June 28, 2025

Submission Date

June 15, 2021

Acceptance Date

September 11, 2021

Published in Issue

Year 2021 Volume: 25 Number: 5

IZ

https://izlik.org/JA82TX95FD

Cite

RIS / Bibtex

APA

Aksoy, H., Şekerler, T., & Mert, N. M. (2025). In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. Journal of Research in Pharmacy, 25(5), 747-754. https://izlik.org/JA82TX95FD

AMA

1.Aksoy H, Şekerler T, Mert NM. In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. J. Res. Pharm. 2025;25(5):747-754. https://izlik.org/JA82TX95FD

Chicago

Aksoy, Halil, Turgut Şekerler, and Naz Mina Mert. 2025. “In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With GSK3-β Protein”. Journal of Research in Pharmacy 25 (5): 747-54. https://izlik.org/JA82TX95FD.

EndNote

Aksoy H, Şekerler T, Mert NM (July 1, 2025) In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. Journal of Research in Pharmacy 25 5 747–754.

IEEE

[1]H. Aksoy, T. Şekerler, and N. M. Mert, “In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein”, J. Res. Pharm., vol. 25, no. 5, pp. 747–754, July 2025, [Online]. Available: https://izlik.org/JA82TX95FD

ISNAD

Aksoy, Halil - Şekerler, Turgut - Mert, Naz Mina. “In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With GSK3-β Protein”. Journal of Research in Pharmacy 25/5 (July 1, 2025): 747-754. https://izlik.org/JA82TX95FD.

JAMA

1.Aksoy H, Şekerler T, Mert NM. In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. J. Res. Pharm. 2025;25:747–754.

MLA

Aksoy, Halil, et al. “In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With GSK3-β Protein”. Journal of Research in Pharmacy, vol. 25, no. 5, July 2025, pp. 747-54, https://izlik.org/JA82TX95FD.

Vancouver

1.Halil Aksoy, Turgut Şekerler, Naz Mina Mert. In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. J. Res. Pharm. [Internet]. 2025 Jul. 1;25(5):747-54. Available from: https://izlik.org/JA82TX95FD