Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening

Damla Kırcı; Yavuz Bülent Köse; Betül Demirci

Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening

Abstract

Hypericum olympicum L. (Hypericaceae) thrives in Turkey, S. Balkans, Greece, and Serbia. While the decoction prepared is internally used for stomachache; used externally for inflamed wounds and cuts in traditional. This research aims to examine the in vitro antimicrobial of the essential oil (EO) obtained using H. olympicum aerial parts. The EOs from H. olympicum aerial parts and roots were distilled and characterized by GC-FID and GC/MS systems, respectively. Germacrene D (26.4%) and α-pinene (8.5%) were found as the main components of the aerial parts of H. olympicum EO. The EO of H. olympicum root were characterized with undecane (38.9%), α-pinene (14.2%), and 3-methyl nonane (9.2%). The antimicrobial activity of EO of H. olympicum aerial parts was observed S. pyogenes (219 µg/mL), E. coli (8.75 mg/mL), S. aureus (109 µg/mL) and C. albicans (55 µg/mL). Essential oil of H. olympicum aerial parts is differently reported in the literature while the chemical composition of EO of H. olympicum root is identified for the first time. According to our findings, the essential oil of the H. olympicum aerial parts showed a strong effect against skin wound pathogens.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Research Article

Authors

Damla Kırcı ^*
0000-0002-3479-3999
Türkiye

Yavuz Bülent Köse
0000-0002-3060-7271
Türkiye

Betül Demirci
Türkiye

Publication Date

June 28, 2025

Submission Date

February 27, 2023

Acceptance Date

May 14, 2023

Published in Issue

Year 2023 Volume: 27 Number: 5

IZ

https://izlik.org/JA62TE56UX

Cite

RIS / Bibtex

APA

Kırcı, D., Köse, Y. B., & Demirci, B. (2025). Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. Journal of Research in Pharmacy, 27(5), 2153-2159. https://izlik.org/JA62TE56UX

AMA

1.Kırcı D, Köse YB, Demirci B. Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. J. Res. Pharm. 2025;27(5):2153-2159. https://izlik.org/JA62TE56UX

Chicago

Kırcı, Damla, Yavuz Bülent Köse, and Betül Demirci. 2025. “Chemical Compositions of Aerial Parts and Root of Hypericum Olympicum L. Essential Oils, and Their Antimicrobial Activity Screening”. Journal of Research in Pharmacy 27 (5): 2153-59. https://izlik.org/JA62TE56UX.

EndNote

Kırcı D, Köse YB, Demirci B (July 1, 2025) Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. Journal of Research in Pharmacy 27 5 2153–2159.

IEEE

[1]D. Kırcı, Y. B. Köse, and B. Demirci, “Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening”, J. Res. Pharm., vol. 27, no. 5, pp. 2153–2159, July 2025, [Online]. Available: https://izlik.org/JA62TE56UX

ISNAD

Kırcı, Damla - Köse, Yavuz Bülent - Demirci, Betül. “Chemical Compositions of Aerial Parts and Root of Hypericum Olympicum L. Essential Oils, and Their Antimicrobial Activity Screening”. Journal of Research in Pharmacy 27/5 (July 1, 2025): 2153-2159. https://izlik.org/JA62TE56UX.

JAMA

1.Kırcı D, Köse YB, Demirci B. Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. J. Res. Pharm. 2025;27:2153–2159.

MLA

Kırcı, Damla, et al. “Chemical Compositions of Aerial Parts and Root of Hypericum Olympicum L. Essential Oils, and Their Antimicrobial Activity Screening”. Journal of Research in Pharmacy, vol. 27, no. 5, July 2025, pp. 2153-9, https://izlik.org/JA62TE56UX.

Vancouver

1.Damla Kırcı, Yavuz Bülent Köse, Betül Demirci. Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. J. Res. Pharm. [Internet]. 2025 Jul. 1;27(5):2153-9. Available from: https://izlik.org/JA62TE56UX