Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS)

Adil Umaz; Fırat Aydın; Özge Tokul Ölmez; Mehmet Fırat; Mehmet Öztürk; Abdulselam Ertaş; Işıl Aydın

Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS)

Abstract

The importance of plants in folk medicine and scientific studies is increasing day by day. In this context, the plants pose a danger to human health when they are eaten by the public, consumed as herbal tea or used as medicinal plants especially the toxic metals in their composition. For this reason, determining the macro, micro and toxic element content in the plants is important for health. In this study; the metal contents of root and aerial parts of nine different Salvia species were determined and the chemometric evaluation of the obtained results was made. In the principal component analysis (PCA) made with 20 elements of Salvia species, it was determined that the first two principal components explained 62.60% of the variance and the first six principal components explained 92.70%. When PCA and hierarchical cluster analysis (HCA) results are evaluated; the parts of Salvia species root and aerial parts were determined that were not clearly separated and there was no regional grouping. In addition, Salvia species prepared as herbal tea was left to different simulated body fluid medium conditions, and the changes in metal contents were examined. It was determined that were taken up Cr, Cd, Pb, Cu, Zn metals in the simulated saliva fluid (SSF), Ni, Mn metals in the simulated gastric fluid (SGF), and Na, K metals in the simulated intestinal fluid (SIF). It was determined that Fe metal in almost all Salvia species was not taken from three simulated body fluid mediums. Thus, elements determined which were taken up in body fluid mediums.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy, Pharmaceutical Chemistry

Journal Section

Research Article

Authors

Adil Umaz ^*
0000-0003-2438-5454
Türkiye

Fırat Aydın
0000-0002-0868-2769
Türkiye

Özge Tokul Ölmez This is me
0000-0002-2093-4949
Türkiye

Mehmet Fırat
0000-0001-5814-614X
Türkiye

Mehmet Öztürk
0000-0001-8932-4535
Türkiye

Abdulselam Ertaş
0000-0002-2193-8386
Türkiye

Işıl Aydın
Türkiye

Publication Date

June 28, 2025

Submission Date

January 23, 2022

Acceptance Date

May 7, 2022

Published in Issue

Year 2022 Volume: 26 Number: 5

IZ

https://izlik.org/JA34GD43JC

Cite

RIS / Bibtex

APA

Umaz, A., Aydın, F., Ölmez, Ö. T., Fırat, M., Öztürk, M., Ertaş, A., & Aydın, I. (2025). Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). Journal of Research in Pharmacy, 26(5), 1281-1294. https://izlik.org/JA34GD43JC

AMA

1.Umaz A, Aydın F, Ölmez ÖT, et al. Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). J. Res. Pharm. 2025;26(5):1281-1294. https://izlik.org/JA34GD43JC

Chicago

Umaz, Adil, Fırat Aydın, Özge Tokul Ölmez, et al. 2025. “Determination and Comparison of Metal Contents in Simulated Body Fluid Medium Conditions of the Plant Species by Flame Atomic Absorption Spectrometry (FAAS)”. Journal of Research in Pharmacy 26 (5): 1281-94. https://izlik.org/JA34GD43JC.

EndNote

Umaz A, Aydın F, Ölmez ÖT, Fırat M, Öztürk M, Ertaş A, Aydın I (June 1, 2025) Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). Journal of Research in Pharmacy 26 5 1281–1294.

IEEE

[1]A. Umaz et al., “Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS)”, J. Res. Pharm., vol. 26, no. 5, pp. 1281–1294, June 2025, [Online]. Available: https://izlik.org/JA34GD43JC

ISNAD

Umaz, Adil - Aydın, Fırat - Ölmez, Özge Tokul - Fırat, Mehmet - Öztürk, Mehmet - Ertaş, Abdulselam - Aydın, Işıl. “Determination and Comparison of Metal Contents in Simulated Body Fluid Medium Conditions of the Plant Species by Flame Atomic Absorption Spectrometry (FAAS)”. Journal of Research in Pharmacy 26/5 (June 1, 2025): 1281-1294. https://izlik.org/JA34GD43JC.

JAMA

1.Umaz A, Aydın F, Ölmez ÖT, Fırat M, Öztürk M, Ertaş A, Aydın I. Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). J. Res. Pharm. 2025;26:1281–1294.

MLA

Umaz, Adil, et al. “Determination and Comparison of Metal Contents in Simulated Body Fluid Medium Conditions of the Plant Species by Flame Atomic Absorption Spectrometry (FAAS)”. Journal of Research in Pharmacy, vol. 26, no. 5, June 2025, pp. 1281-94, https://izlik.org/JA34GD43JC.

Vancouver

1.Adil Umaz, Fırat Aydın, Özge Tokul Ölmez, Mehmet Fırat, Mehmet Öztürk, Abdulselam Ertaş, Işıl Aydın. Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). J. Res. Pharm. [Internet]. 2025 Jun. 1;26(5):1281-94. Available from: https://izlik.org/JA34GD43JC