Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey?

Zehra Bektur; Methiye Mancak; Ufuk Koca Çalışkan

Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey?

Abstract

Humulus lupulus L. (Hops), which belongs to the Cannabaceae family, originates from Asia and grows naturally in geographies with temperate climates such as Europe and North America. H. lupulus might have been brought to Turkey from Germany to be used mostly in beer production. The plant is also used for medicinal purposes due to its sedative and phytoestrogenic effects all over the world. Pharmacopoeia analyzes are important to confirm whether the subject drog has the properties specified in the pharmacopoeia in order to check its suitability before it is used for health purposes. For this reason, we aimed to evaluate features of the variety of hops plants: 1-cultivated in Bilecik/Turkey; 2-sold by herbalists and sold on online shopping sites. Obtained samples of hops were analyzed according to the 'Lupuli flos' monograph provided within the European Pharmacopoeia 8.0 (EP 8.0). Macroscopic, microscopic, thin-layer chromatography, matter extractable by ethanol, loss on drying analyzes and determination of total ash amount of the samples were conducted according to the EP 8.0. As a result, the hop samples, except those cultured in Turkey, were not suitable for the EP 8.0. Legal controls should be provided by the authorities on herbals sold by herbalists and on the internet. Samples of hops cultured for use in beer production in Turkey were suitable for pharmacopoeia. These samples should meet the public at secure sales points or in food supplements in Turkey.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacognosy

Journal Section

Research Article

Authors

Zehra Bektur This is me
0000-0002-2229-3284
Türkiye

Methiye Mancak
0000-0002-0085-7552
Türkiye

Ufuk Koca Çalışkan ^*
Türkiye

Publication Date

June 28, 2025

Submission Date

March 11, 2022

Acceptance Date

May 22, 2022

Published in Issue

Year 2022 Volume: 26 Number: 5

IZ

https://izlik.org/JA92WF49EJ

Cite

RIS / Bibtex

APA

Bektur, Z., Mancak, M., & Çalışkan, U. K. (2025). Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey? Journal of Research in Pharmacy, 26(5), 1304-1316. https://izlik.org/JA92WF49EJ

AMA

1.Bektur Z, Mancak M, Çalışkan UK. Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey? J. Res. Pharm. 2025;26(5):1304-1316. https://izlik.org/JA92WF49EJ

Chicago

Bektur, Zehra, Methiye Mancak, and Ufuk Koca Çalışkan. 2025. “Which Humulus Lupulus Drug Samples Meet the European Pharmacopoeia Criteria: Cultivated, Obtained from the Herbalists or Online Shopping Sites in Turkey?”. Journal of Research in Pharmacy 26 (5): 1304-16. https://izlik.org/JA92WF49EJ.

EndNote

Bektur Z, Mancak M, Çalışkan UK (June 1, 2025) Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey? Journal of Research in Pharmacy 26 5 1304–1316.

IEEE

[1]Z. Bektur, M. Mancak, and U. K. Çalışkan, “Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey?”, J. Res. Pharm., vol. 26, no. 5, pp. 1304–1316, June 2025, [Online]. Available: https://izlik.org/JA92WF49EJ

ISNAD

Bektur, Zehra - Mancak, Methiye - Çalışkan, Ufuk Koca. “Which Humulus Lupulus Drug Samples Meet the European Pharmacopoeia Criteria: Cultivated, Obtained from the Herbalists or Online Shopping Sites in Turkey?”. Journal of Research in Pharmacy 26/5 (June 1, 2025): 1304-1316. https://izlik.org/JA92WF49EJ.

JAMA

1.Bektur Z, Mancak M, Çalışkan UK. Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey? J. Res. Pharm. 2025;26:1304–1316.

MLA

Bektur, Zehra, et al. “Which Humulus Lupulus Drug Samples Meet the European Pharmacopoeia Criteria: Cultivated, Obtained from the Herbalists or Online Shopping Sites in Turkey?”. Journal of Research in Pharmacy, vol. 26, no. 5, June 2025, pp. 1304-16, https://izlik.org/JA92WF49EJ.

Vancouver

1.Zehra Bektur, Methiye Mancak, Ufuk Koca Çalışkan. Which Humulus lupulus drug samples meet the European Pharmacopoeia criteria: Cultivated, obtained from the herbalists or online shopping sites in Turkey? J. Res. Pharm. [Internet]. 2025 Jun. 1;26(5):1304-16. Available from: https://izlik.org/JA92WF49EJ