Research Article

Antimicrobial activity of three Scutellaria L. species from Turkey

Volume: 23 Number: 3 June 27, 2025

Antimicrobial activity of three Scutellaria L. species from Turkey

Abstract

Plant-sourced antimicrobials are known for their therapeutic potency against multi-drug-resistant pathogens. The members of Scutellaria L. have been used to cure several diseases in East Asia, Europe, and North America. The genus Scutellaria belonging to Lamiaceae family is composed of around 360 species worldwide and 18 species in Turkey. In this study, 36 extracts prepared with different solvents from aerial parts and roots of S. salviifolia Benth., S. diffusa Benth. and S. pontica C. Koch were investigated for their antimicrobial activity against four bacteria (Escherichia coli ATCC 25922, Enterococcus faecalis ATCC 29212, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 29213) and three yeasts (Candida albicans ATCC 90028, C. krusei ATCC 6258, C. parapsilosis ATCC 90018) by using the broth microdilution method. Gentamicin, vancomycin and fluconazole were used as positive control. According to our results, all of the tested extracts showed stronger antimicrobial activity against yeasts than bacteria. The chloroform extract of S. salviifolia root showed the highest antifungal effect against C. krusei with 32 μg/ml MIC value compared with all the tested extracts and the positive control fluconazole (64 μg/ml MIC value).

Keywords

References

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Details

Primary Language

English

Subjects

Pharmaceutical Botany

Journal Section

Research Article

Authors

Melike Ekizoğlu This is me
Türkiye

Nurten Ezer This is me
Türkiye

Publication Date

June 27, 2025

Submission Date

October 2, 2018

Acceptance Date

December 28, 2018

Published in Issue

Year 2019 Volume: 23 Number: 3

APA
Arıtuluk, Z. C., Özkul, C., Renda, G., Ekizoğlu, M., & Ezer, N. (2025). Antimicrobial activity of three Scutellaria L. species from Turkey. Journal of Research in Pharmacy, 23(3), 552-558. https://izlik.org/JA43KB79UT
AMA
1.Arıtuluk ZC, Özkul C, Renda G, Ekizoğlu M, Ezer N. Antimicrobial activity of three Scutellaria L. species from Turkey. J. Res. Pharm. 2025;23(3):552-558. https://izlik.org/JA43KB79UT
Chicago
Arıtuluk, Zekiye Ceren, Ceren Özkul, Gülin Renda, Melike Ekizoğlu, and Nurten Ezer. 2025. “Antimicrobial Activity of Three Scutellaria L. Species from Turkey”. Journal of Research in Pharmacy 23 (3): 552-58. https://izlik.org/JA43KB79UT.
EndNote
Arıtuluk ZC, Özkul C, Renda G, Ekizoğlu M, Ezer N (June 1, 2025) Antimicrobial activity of three Scutellaria L. species from Turkey. Journal of Research in Pharmacy 23 3 552–558.
IEEE
[1]Z. C. Arıtuluk, C. Özkul, G. Renda, M. Ekizoğlu, and N. Ezer, “Antimicrobial activity of three Scutellaria L. species from Turkey”, J. Res. Pharm., vol. 23, no. 3, pp. 552–558, June 2025, [Online]. Available: https://izlik.org/JA43KB79UT
ISNAD
Arıtuluk, Zekiye Ceren - Özkul, Ceren - Renda, Gülin - Ekizoğlu, Melike - Ezer, Nurten. “Antimicrobial Activity of Three Scutellaria L. Species from Turkey”. Journal of Research in Pharmacy 23/3 (June 1, 2025): 552-558. https://izlik.org/JA43KB79UT.
JAMA
1.Arıtuluk ZC, Özkul C, Renda G, Ekizoğlu M, Ezer N. Antimicrobial activity of three Scutellaria L. species from Turkey. J. Res. Pharm. 2025;23:552–558.
MLA
Arıtuluk, Zekiye Ceren, et al. “Antimicrobial Activity of Three Scutellaria L. Species from Turkey”. Journal of Research in Pharmacy, vol. 23, no. 3, June 2025, pp. 552-8, https://izlik.org/JA43KB79UT.
Vancouver
1.Zekiye Ceren Arıtuluk, Ceren Özkul, Gülin Renda, Melike Ekizoğlu, Nurten Ezer. Antimicrobial activity of three Scutellaria L. species from Turkey. J. Res. Pharm. [Internet]. 2025 Jun. 1;23(3):552-8. Available from: https://izlik.org/JA43KB79UT