Design of a novel colorimetric method based on AuNPs for tazobactam and piperacillin

Zehra Özden Erdoğan; Hakan Balcı

Design of a novel colorimetric method based on AuNPs for tazobactam and piperacillin

Abstract

In the present paper, a colorimetric method for the determination of tazobactam and piperacillin based on plasmonic nanoparticles (AuNPs) is suggested. Plasmonic nanoparticles have gained interest for application in the creation of sensitive analytical techniques because of their unique features. The localized surface plasmon resonance (LSPR) absorption band for AuNPs with a wavelength 543.5 (A543.5) nm was used for analysis. The working parameters such as the amount of AuNPs and pH were optimized to obtain the optimum experimental conditions. The calibration curve for the colorimetric method was prepared with tazobactam and piperacillin concentrations ranging from 2.25- 30.04 mg/L and0.52-10.33 mg/L, respectively. The detection limits were found to be 1.01 mg/L for tazobactam and 0.29 mg/L for piperacillin The AuNPs-based colorimetric method suggested in this work can use as an alternative analytical method for routine analysis of tazobactam and piperacillin because it is quick, simple, and affordable.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmacology and Pharmaceutical Sciences (Other)

Journal Section

Research Article

Authors

Zehra Özden Erdoğan ^*
0000-0002-1687-973X
Türkiye

Hakan Balcı
0000-0003-4106-3211
Türkiye

Publication Date

June 28, 2025

Submission Date

November 4, 2022

Acceptance Date

January 30, 2023

Published in Issue

Year 2023 Volume: 27 Number: 3

IZ

https://izlik.org/JA55NE88BL

Cite

RIS / Bibtex

APA

Erdoğan, Z. Ö., & Balcı, H. (2025). Design of a novel colorimetric method based on AuNPs for tazobactam and piperacillin. Journal of Research in Pharmacy, 27(3), 1066-1075. https://izlik.org/JA55NE88BL

AMA

1.Erdoğan ZÖ, Balcı H. Design of a novel colorimetric method based on AuNPs for tazobactam and piperacillin. J. Res. Pharm. 2025;27(3):1066-1075. https://izlik.org/JA55NE88BL

Chicago

Erdoğan, Zehra Özden, and Hakan Balcı. 2025. “Design of a Novel Colorimetric Method Based on AuNPs for Tazobactam and Piperacillin”. Journal of Research in Pharmacy 27 (3): 1066-75. https://izlik.org/JA55NE88BL.

EndNote

Erdoğan ZÖ, Balcı H (June 1, 2025) Design of a novel colorimetric method based on AuNPs for tazobactam and piperacillin. Journal of Research in Pharmacy 27 3 1066–1075.

IEEE

[1]Z. Ö. Erdoğan and H. Balcı, “Design of a novel colorimetric method based on AuNPs for tazobactam and piperacillin”, J. Res. Pharm., vol. 27, no. 3, pp. 1066–1075, June 2025, [Online]. Available: https://izlik.org/JA55NE88BL

ISNAD

Erdoğan, Zehra Özden - Balcı, Hakan. “Design of a Novel Colorimetric Method Based on AuNPs for Tazobactam and Piperacillin”. Journal of Research in Pharmacy 27/3 (June 1, 2025): 1066-1075. https://izlik.org/JA55NE88BL.

JAMA

1.Erdoğan ZÖ, Balcı H. Design of a novel colorimetric method based on AuNPs for tazobactam and piperacillin. J. Res. Pharm. 2025;27:1066–1075.

MLA

Erdoğan, Zehra Özden, and Hakan Balcı. “Design of a Novel Colorimetric Method Based on AuNPs for Tazobactam and Piperacillin”. Journal of Research in Pharmacy, vol. 27, no. 3, June 2025, pp. 1066-75, https://izlik.org/JA55NE88BL.

Vancouver

1.Zehra Özden Erdoğan, Hakan Balcı. Design of a novel colorimetric method based on AuNPs for tazobactam and piperacillin. J. Res. Pharm. [Internet]. 2025 Jun. 1;27(3):1066-75. Available from: https://izlik.org/JA55NE88BL