Evaluation of the Effect of Buparvaquone Used in the Treatment of Neonatal Calves Naturally Infected with Cryptosporidium Spp. on Renal and Hepatic Functions

Year 2023, , 118 - 123, 31.12.2023

Fatma Zehra Evci Güney , Sezgin Şentürk

https://doi.org/10.30782/jrvm.1358532

Abstract

Cryptosporidium parvum is a zoonotic protozoan that causes neonatal calf diarrhea common in the world. Buparvaquone, which is known to
have very positive effects on oocysts, which are the main reserve in the spread of infection, has not yet been investigated for its hemato-biochemical
aspect in calves with cryptosporidiosis. In the present study, the effect of buparvaquone on renal and hepatic functions in naturally
infected newborn calves with cryptosporidiosis was investigated. A group was formed for this study using only a total of ten calves (n=10)
naturally infected with cryptosporidiosis. Buparvaquone 2.5 mg/kg intramuscular injection was administered as a single dose to all calves in
the group. Laboratory analyses and statistical calculations of blood and serum samples taken on the specified days were made. According to
the results we obtained in the study, it was observed that the renal and hepatic effects of the drug after a single dose injection of buparvaquone
to calves with neonatal cryptosporidiosis remained within normal limits, similar to the methods safely applied in the treatment of cryptosporidiosis
in the field.

Keywords

Cryptosporidiosis, calves, renal, hepatic, buparvaquone

Ethical Statement

I state that the study titled “Evaluation of the effect of buparvaquone used in the treatment of neonatal calves naturally infected with cryptosporidiosis on renal and hepatic functions” was prepared in accordance with scientific ethical rules in all processes from the research phase to its conclusion and that the works I have used consist of those shown in the resources section, and I declare.

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