Antioxidant properties of hawthorn vinegar and its potential role in bone health

Year 2025, Volume: 44 Issue: 2, 95 - 103, 31.12.2025

Bayram Süzer , Murat Horasan , Nilay Seyidoğlu , Deniz Karakcı

https://doi.org/10.30782/jrvm.1793251

Abstract

This is the first study to evaluate the effects of ultrasound-treated hawthorn vinegar on bone biomechanical performance, plasma biochemical markers, and bone ash content. The findings provide new insights into how bioactive compounds in vinegar can support skeletal health. The objective of this study is to evaluate the effects of ultrasound-treated hawthorn vinegar on bone health by assessing its impact on bone biomechanics, mineral metabolism, and biochemical properties in rats. Our study investigated the effects of ultrasound-treated hawthorn vinegar on bone biomechanics, biochemical properties, and overall bone quality. Forty female rats were randomly assigned to control and experimental groups, receiving either untreated or ultrasound-treated hawthorn vinegar at doses of 0.5 ml/kg and 1 ml/kg. To assess the potential benefits of hawthorn vinegar on skeletal health, we analyzed bone mechanical properties, plasma and intestinal calcium and phosphorus levels, cortical bone area, and bone ash content. The results revealed that rats receiving ultrasound-treated hawthorn vinegar exhibited a significant increase in ultimate moment values, reduced maximum angles at failure, and higher energy to failure values compared to the control group, indicating enhanced bone strength. Additionally, it led to increased plasma calcium levels, reduced intestinal phosphorus concentrations, and higher tibial ash content. These findings suggest that ultrasound-treated hawthorn vinegar may promote bone health by improving biomechanical strength and mineral metabolism, thereby contributing to overall bone quality. The findings highlight the beneficial effects of hawthorn vinegar on bone health, attributed to its high antioxidant and phenolic content. As the first to compare ultrasound-treated and untreated hawthorn vinegar, the results emphasize the role of bioactive compounds in enhancing bone biomechanics, suggesting its potential as a functional food for skeletal health.

Keywords

Biomechanics , Bone health , Hawthorn , Ultrasound-treatment , Vinegar

Ethical Statement

The current study protocol was approved by Tekirdag Namik Kemal University Animal Experiments Local Ethics Committee (Approval Number: T2022-979).

Supporting Institution

Tekirdag Namik Kemal University

Project Number

NKUBAP.10.GA.21.346

Alıç sirkesinin antioksidan özellikleri ve kemik sağlığındaki potansiyel rolü

Abstract

Bu çalışma, ultrasonla muamele edilmiş alıç sirkesinin kemik biyomekanik performansı, plazma biyokimyasal belirteçleri ve kemik kül içeriği üzerindeki etkilerini değerlendiren ilk araştırmadır. Bulgular, sirkedeki biyoaktif bileşiklerin iskelet sağlığını nasıl destekleyebileceğine dair yeni içgörüler sunmaktadır. Bu çalışmanın amacı, ultrasonla muamele edilmiş alıç sirkesinin kemik sağlığı üzerindeki etkilerini; kemik biyomekaniği, mineral metabolizması ve biyokimyasal özellikler üzerindeki etkilerini değerlendirerek incelemektir. Çalışmamızda, ultrasonla muamele edilmiş alıç sirkesinin kemik biyomekaniği, biyokimyasal özellikleri ve genel kemik kalitesi üzerindeki etkileri araştırılmıştır. Kırk dişi sıçan rastgele kontrol ve deney gruplarına ayrılmış, gruplara işlenmemiş veya ultrasonla muamele edilmiş alıç sirkesi 0.5 ml/kg ve 1 ml/kg dozlarda uygulanmıştır. Alıç sirkesinin iskelet sağlığı üzerindeki olası faydalarını değerlendirmek amacıyla kemik mekanik özellikleri, plazma ve bağırsak kalsiyum ve fosfor düzeyleri, kortikal kemik alanı ve kemik kül içeriği analiz edilmiştir. Sonuçlar, ultrasonla muamele edilmiş alıç sirkesi verilen sıçanlarda, kontrol grubuna kıyasla nihai moment değerlerinde anlamlı artış, kırılmada maksimum açılarda azalma ve kırılmaya kadar geçen enerji değerlerinde artış olduğunu ortaya koymuştur; bu da kemik dayanıklılığının arttığını göstermektedir. Ayrıca plazma kalsiyum düzeylerinde artış, bağırsak fosfor konsantrasyonlarında azalma ve tibia kül içeriğinde yükselme gözlenmiştir. Bu bulgular, ultrasonla muamele edilmiş alıç sirkesinin biyomekanik dayanıklılığı ve mineral metabolizmasını iyileştirerek kemik sağlığını destekleyebileceğini, dolayısıyla genel kemik kalitesine katkıda bulunabileceğini düşündürmektedir. Bulgular ayrıca alıç sirkesinin yüksek antioksidan ve fenolik içeriğine bağlı olarak kemik sağlığı üzerindeki faydalı etkilerini vurgulamaktadır. Ultrasonla muamele edilmiş ve edilmemiş alıç sirkesinin karşılaştırıldığı ilk çalışma olması nedeniyle, elde edilen sonuçlar biyoaktif bileşiklerin kemik biyomekaniğini geliştirmedeki rolünü ortaya koymakta ve alıç sirkesinin iskelet sağlığı için işlevsel bir gıda olarak potansiyeline işaret etmektedir.

Keywords

Biyomekanik , Kemik sağlığı , Alıç , Ultrasonla muamele , Sirke

Ethical Statement

Mevcut çalışma protokolü Tekirdağ Namık Kemal Üniversitesi Hayvan Deneyleri Yerel Etik Kurulu tarafından onaylanmıştır (Onay Numarası: T2022-979).

Supporting Institution

Tekirdağ Namık Kemal Üniversitesi

Project Number

NKUBAP.10.GA.21.346

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