Synthesis, characterization and biological studies of metal complexes of 4-iodo-n-(6-sulfamoylbenzothiazol-2-yl)benzamide

Halil İlkimen; Tuğçe Öztürk; Cengiz Yenikaya; Aysel Gülbandılar

doi:10.59313/jsr-a.1666840

Synthesis, characterization and biological studies of metal complexes of 4-iodo-n-(6-sulfamoylbenzothiazol-2-yl)benzamide

Abstract

In this study, the new 4-iodo-N-(6-sulfamoylbenzothiazol-2-yl)benzamide (L3) obtained from 2-amino-6-sulfamoylbenzothiazole (L1) and 4-iodobenzoyl chloride (L2) and Fe(II) {[Fe(L3)2(SO4)].H2O (1)}, Ni(II) {[Ni(L3)2(Ac)2].2H2O (2)} and Cu(II) {[Cu(L3)2(Ac)2].2H2O (3)} complexes were synthesized. The structures were synthesized by elemental analysis for L3 and 1-3, infrared spectroscopy (IR) for L3 and 1-3, nuclear magnetic resonance (NMR) for L3, atomic absorption spectroscopy (AAS), molar conductivity, and magnetic susceptibility methods for 1-3. As a consequence of spectroscopic evaluation, it was determined that compounds 1-3 exhibited a non-ionic and tetrahedral conformation. A comprehensive examination was conducted on the susceptibility of all substances to C. albicans (yeast), L. monocytogenes, E. faecalis, E. coli, P. aeruginosa, S. aureus, and B. subtilis (bacteria) were thoroughly investigated. The antimicrobial activities were contrasted with those of Ketoconazole, Fluconazole, Levofloxacin, Chloramphenicol, Vancomycin, and Cefepime.

Keywords

Project Number

Kütahya Dumlupinar University Research Fund (Grant No. 2024/16).

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Details

Primary Language

English

Subjects

Transition Metal Chemistry

Journal Section

Research Article

Authors

Halil İlkimen ^*
0000-0003-1747-159X
Türkiye

Tuğçe Öztürk
0000-0003-1885-0700
Türkiye

Cengiz Yenikaya
0000-0002-5867-9146
Türkiye

Aysel Gülbandılar
0000-0001-9075-9923
Türkiye

Publication Date

June 30, 2025

Submission Date

March 27, 2025

Acceptance Date

June 16, 2025

Published in Issue

Year 2025 Number: 061

DOI

https://doi.org/10.59313/jsr-a.1666840

IZ

https://izlik.org/JA48SZ86TS

Cite

RIS / Bibtex

APA

İlkimen, H., Öztürk, T., Yenikaya, C., & Gülbandılar, A. (2025). Synthesis, characterization and biological studies of metal complexes of 4-iodo-n-(6-sulfamoylbenzothiazol-2-yl)benzamide. Journal of Scientific Reports-A, 061, 125-136. https://doi.org/10.59313/jsr-a.1666840

AMA

1.İlkimen H, Öztürk T, Yenikaya C, Gülbandılar A. Synthesis, characterization and biological studies of metal complexes of 4-iodo-n-(6-sulfamoylbenzothiazol-2-yl)benzamide. JSR-A. 2025;(061):125-136. doi:10.59313/jsr-a.1666840

Chicago

İlkimen, Halil, Tuğçe Öztürk, Cengiz Yenikaya, and Aysel Gülbandılar. 2025. “Synthesis, Characterization and Biological Studies of Metal Complexes of 4-Iodo-N-(6-Sulfamoylbenzothiazol-2-Yl)benzamide”. Journal of Scientific Reports-A, nos. 061: 125-36. https://doi.org/10.59313/jsr-a.1666840.

EndNote

İlkimen H, Öztürk T, Yenikaya C, Gülbandılar A (June 1, 2025) Synthesis, characterization and biological studies of metal complexes of 4-iodo-n-(6-sulfamoylbenzothiazol-2-yl)benzamide. Journal of Scientific Reports-A 061 125–136.

IEEE

[1]H. İlkimen, T. Öztürk, C. Yenikaya, and A. Gülbandılar, “Synthesis, characterization and biological studies of metal complexes of 4-iodo-n-(6-sulfamoylbenzothiazol-2-yl)benzamide”, JSR-A, no. 061, pp. 125–136, June 2025, doi: 10.59313/jsr-a.1666840.

ISNAD

İlkimen, Halil - Öztürk, Tuğçe - Yenikaya, Cengiz - Gülbandılar, Aysel. “Synthesis, Characterization and Biological Studies of Metal Complexes of 4-Iodo-N-(6-Sulfamoylbenzothiazol-2-Yl)benzamide”. Journal of Scientific Reports-A. 061 (June 1, 2025): 125-136. https://doi.org/10.59313/jsr-a.1666840.

JAMA

1.İlkimen H, Öztürk T, Yenikaya C, Gülbandılar A. Synthesis, characterization and biological studies of metal complexes of 4-iodo-n-(6-sulfamoylbenzothiazol-2-yl)benzamide. JSR-A. 2025;:125–136.

MLA

İlkimen, Halil, et al. “Synthesis, Characterization and Biological Studies of Metal Complexes of 4-Iodo-N-(6-Sulfamoylbenzothiazol-2-Yl)benzamide”. Journal of Scientific Reports-A, no. 061, June 2025, pp. 125-36, doi:10.59313/jsr-a.1666840.

Vancouver

1.Halil İlkimen, Tuğçe Öztürk, Cengiz Yenikaya, Aysel Gülbandılar. Synthesis, characterization and biological studies of metal complexes of 4-iodo-n-(6-sulfamoylbenzothiazol-2-yl)benzamide. JSR-A. 2025 Jun. 1;(061):125-36. doi:10.59313/jsr-a.1666840