Comparision between Direct Stenting and Stenting after Pre-dilatation Using TIMI Frame Count in Stable Coronary Artery Disease
Abstract
Introduction:
There are limited data comparing the effects of
direct stenting and stenting after balloon percutaneous transluminal coronary
angioplasty (PTCA) on coronary flow in patients with stable coronary artery disease
(CAD). This study was designed to evaluate the effects of direct stenting and
stenting after balloon PTCA on coronary flow using TIMI frame count (TFC) in
patients with stable CAD.
Patients
and Methods: After a retrospective review of patients who underwent
percutaneous coronary intervention (PCI) from 2008 to 2012, we identified and
included 55 patients who underwent direct stenting and 42 patients who received
stenting after balloon PTCA. PCI records of the two study groups were reviewed
to re-calculate pre- and post-PCI TFCs for comparison.
Results:
The average pre- and post-procedural TFC values
were 18.72 frames per second (fps) and 16.12 fps (difference 2.6 fps),
respectively, in the direct stenting group. The corresponding TFC values were
18.13 fps and 16.63 fps (difference 1.5 fps) in the stenting after balloon PTCA
group. The two groups differed significantly with respect to post-procedural
decreases in TFC (p< 0.001).
Conclusion:
Our findings show that, compared to stenting after
balloon PTCA, direct stenting is more successful in terms of improved antegrade
coronary blood flow in stable CAD patients, which suggests that direct stenting
may contribute to better microvascular circulation.
Keywords
References
- 1. Martinez-Elbal L, Ruiz-Nodar JM, Zueco J, López-Minguez JR, Moreu J, Calvo I, et al. Direct coronary stenting versus stenting with balloon pre-dilation: immediate and follow-up results of a multicentre, prospective, randomized study. The DISCO trial. Direct stenting of coronary arteries. Eur Heart J 2002;23:633-40.
- 2. Weber F, Schneider H, Warzok F, Petzsch M, von Knorre GH, Nienaber CA. Randomized comparison of direct and provisional stenting in de novo coronary artery lesions: the RADICAL study. Z Kardiol 2003;92:173-81.
- 3. Özdemir R, Sezgin AT, Barutcu I, Topal E, Güllü H, Açıkgöz N. Comparison of direct stenting versus conventional stent implantation on blood flow in patients with ST-segment elevation myocardial infarction. Angiology 2006;57:453-8.
- 4. Gibson CM, Cannon CP, Daley WL, Dodge JT Jr, Alexander B Jr, Marble SJ, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 1996;93:879-88.
- 5. Rogers C, Karnovsky MJ, Edelman ER. Inhibition of experimental neointimal hyperplasia and thrombosis depends on the type of vascular injury and the site of drug administration. Circulation 1993;88:1215-21.
- 6. Schwartz RS, Huber KC, Murphy JG, Edwards WD, Camrud AR, Vlietstra RE, et al. Restenosis and the proportional neointimal response to coronary artery injury: results in a porcine model. J Am Coll Cardiol 1992;19:267-74.
- 7. Alidoosti M, Salarifar M, Kassaian SE, Zeinali AM, Fathollahi MS, Dehkordi MR. In-hospital and mid-term adverse clinical outcomes of a direct stenting strategy versus stenting after predilatation for the treatment of coronary artery lesions. Cardiovasc J Afr 2008;19:297-302.
- 8. Baim DS, Flatley M, Caputo R, O’Shaughnessy C, Low R, Fanelli C, et al. Comparison of PRE-dilatation vs direct stenting in coronary treatment using the Medtronic AVE S670 Coronary Stent System (The PREDICT trial). Am J Cardiol 2001;88:1364-9.
Details
Primary Language
English
Subjects
Clinical Sciences
Journal Section
Research Article
Authors
Bahri Akdeniz
This is me
Ömer Şenarslan
This is me
Mehmet Akif Ekinci
This is me
Abdurrahman Arslan
This is me
Fatih Aytemiz
This is me
İlhan Koyuncu
This is me
Barış Ünal
This is me
Betül Koyuncu
This is me
Publication Date
December 1, 2015
Submission Date
December 1, 2015
Acceptance Date
-
Published in Issue
Year 2015 Volume: 18 Number: 3