Relation of Troponin I Levels with Postoperative Mortality and Morbidity Rates in Patients Followed in Intensive Care Unit After Congenital Cardiac Surgery Whose Ages Between 7 Days and 16 Years Old

Yıl 2018, Cilt: 21 Sayı: 1, 43 - 48, 01.04.2018

Hülya Yılmaz Ak Mustafa Yıldız Nurgül Yurtseven Deniz Özsoy Doğaç Okşen Hakkı Kürşat Çetin

Öz

Introduction:
Troponin
I levels are the most important predictive marker of myocardial injury.
Myocardial injury has been reported as the most significant cause of morbidity
and mortality in pediatric cardiac surgery. In this study, we aimed to evaluate
the effect of troponin I on postoperative mortality and morbidity in the child
population.

Patients
and Methods: Ninety-nine patients to whom congenital cardiac surgery
were included in this study. Perioperative and postoperative troponin I values
at 24^th and 48^th hours were recorded. Patients were
divided into two groups according to troponin I values at 24^th hour
(lower and higher than 15 ng/mL, respectively). Aortic cross-clamp time,
cardiopulmonary bypass (CPB) time, intubation time, and the duration of
intensive care unit stay and medication of inotropic agents were recorded.

Results: Postoperative
troponin I levels at 24^th hour were higher than 15 ng/mL in patients
who underwent congenital cardiac surgery and were related with significantly
higher CPB, aortic cross-clamp, intubation time, and longer stay in intensive
care unit.

Conclusion: Higher troponin I levels at
24^th hour are associated with increased morbidity in patients who
undergo congenital cardiac surgery.

Anahtar Kelimeler

Congenital cardiac surgery, troponin I, mortality, morbidity

Konjenital Kardiyak Cerrahi Sonrası Yoğun Bakım Ünitesinde Takip Edilen 7 Gün ile 16 Yaş Aralığındaki Hastalarda Troponin I Seviyelerinin Postoperatif Mortalite ve Morbidite ile İlişkisi

Öz

Giriş: Troponin I miyokardiyal hasarın tahmininde önemli bir belirteçtir.
Pediyatrik kardiyak cerrahide miyokardiyal hasarın en önemli mortalite ve
morbidite nedeni olduğu anlaşılmıştır. Bu çalışma ile konjenital kalp ameliyatı
olan çocuklarda troponin I değerlerinin postoperatif mortalite ve morbidite
üzerine etkisini değerlendirmek amaçlanmıştır.

Hastalar ve
Yöntem: Konjenital kardiyak cerrahi uygulanan 99 hastanın
perioperatif, postoperatif 24. ve 48. saatteki troponin I değerleri kaydedildi.
Hastalar hesaplanan cut off değerine göre 24. saat troponin I seviyelerine göre
iki gruba ayrıldı (15 ng/mL’den yüksek olanlar ve olmayanlar). Hastaların
aortik kros klemp süreleri, kardiyopulmoner baypas süresi, entübasyon süresi,
yoğun bakımda kalış süresi ve inotropik ajan düzeyleri kaydedildi.

Bulgular: Konjenital kalp ameliyatı olan hastalarda postoperatif 24. saatte ölçülen
troponin I seviyelerinin 15 ng/mL’nin üzerinde olmasının: kardiyopulmoner
baypas süresi, aortik kross klamp süresi, entübasyon süresi ve yoğun bakım kalış
süresini anlamlı olarak arttırdığı gösterildi.

Sonuç: Konjenital kalp ameliyatı
olan hastalarda postoperatif 24. saat yüksek troponin I düzeyleri yüksek
morbidite riski ile uyumludur.

Anahtar Kelimeler

Konjenital kalp ameliyatı, mortalite, morbidite, troponin I

Kaynakça

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