Research Article

Relationship Between Severity of Obstructive Sleep Apnea and PR Interval

Volume: 19 Number: 1 April 4, 2016
  • Harun Karamanlı *
  • Fatih Aygün
  • Recep Akgedik
TR EN

Relationship Between Severity of Obstructive Sleep Apnea and PR Interval

Abstract

Introduction: Relationship between obstructive sleep apnea (OSA) and electrocardiogram and OSA severity index relationship that may affect the PR interval were studied.

Patients and Methods: This study included 85 people who had OSA diagnosed at our clinic between January 2013 and August 2013. Their polysomnography (PSG) reports were evaluated by physicians who are expert in their fields. Individuals with severe OSA diseases were categorized as group 1, and individuals with mild to moderate OSA were categorized as group 2.

Results: Age distribution of individuals who participated to the study ranged from 20 years to 85 years (mean ± standard deviation, 45.5 ± 13.2 years). Fifty-one (60%) of those individuals were men, and 34 (40%) of them were women. The PR interval for the group who had severe OSA on PSG (group 1) was 163.1 ± 35.2 ms, and it was 147.8 ± 29.3 in group 2.

Conclusion: It was observed that individuals having severe OSA had higher PR intervals than individuals who had mild to moderate OSA. It was determined that results were statistically significant (p< 0.05, p= 0.032). We believe that apnea-hypopnea index, oxygen desaturation index, and arousal values, which are indications of OSA severity and parameters of hypoxia-reoxygenation, contribute to PR prolongation.

Keywords

References

  1. 1. Bonsignore MR, Marrone O, Insalaco G, Bonsignore G. The cardiovascular effects of obstructive sleep apnoeas: analysis of pathogenic mechanisms. Eur Respir J 1994;7:786-805.
  2. 2. Fletcher EC, DeBehnke RD, Lovoi MS, Gorin AB. Undiagnosed sleep apnea in patients with essential hypertension. Ann Intern Med 1985;103:190-5.
  3. 3. Peker Y, Hedner J, Norum J, Kraiczi H, Carlson J. Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: a 7-year follow-up. Am J Respir Crit Care Med 2002;166:159-65.
  4. 4. Gami AS, Howard DE, Olson EJ, Somers VK. Day-night pattern of sudden death in obstructive sleep apnea. N Engl J Med 2005;352:1206-14.
  5. 5. Huikuri HV, Castellanos A, Myerburg RJ, Sudden death due to cardiac arrhythmias. N Engl J Med 2001;345:1473-82.
  6. 6. O’Driscoll DM, Meadows GE, Corfield DR, Simonds AK, Morrell MJ. Cardiovascular response to arousal from sleep under controlled conditions of central and peripheral chemoreceptor stimulation in humans. J Appl Physiol (1985) 2004;96:865-70.
  7. 7. Otto ME, Belohlavek M, Romero-Corral A, Gami AS, Gilman G, Svatikova A, et al. Comparison of cardiac structural and functional changes in obese otherwise healthy adults with versus without obstructive sleep apnea. Am J Cardiol 2007;99:1298-302.
  8. 8. Chung M-H, Kuo TBJ, Hsu N, Chu H, Chou K-R, Yang CCH. Sleep and autonomic nervous system changes - enhanced cardiac sympathetic modulations during sleep in permanent night shift nurses. Scand J Work Environ Health 2009;35:180-7.

Details

Primary Language

English

Subjects

Clinical Sciences

Journal Section

Research Article

Authors

Harun Karamanlı * This is me

Fatih Aygün This is me

Recep Akgedik This is me

Publication Date

April 4, 2016

Submission Date

April 4, 2016

Acceptance Date

-

Published in Issue

Year 2016 Volume: 19 Number: 1

APA
Karamanlı, H., Aygün, F., & Akgedik, R. (2016). Relationship Between Severity of Obstructive Sleep Apnea and PR Interval. Koşuyolu Heart Journal, 19(1), 27-31. https://izlik.org/JA57ZP37YY
AMA
1.Karamanlı H, Aygün F, Akgedik R. Relationship Between Severity of Obstructive Sleep Apnea and PR Interval. Koşuyolu Heart Journal. 2016;19(1):27-31. https://izlik.org/JA57ZP37YY
Chicago
Karamanlı, Harun, Fatih Aygün, and Recep Akgedik. 2016. “Relationship Between Severity of Obstructive Sleep Apnea and PR Interval”. Koşuyolu Heart Journal 19 (1): 27-31. https://izlik.org/JA57ZP37YY.
EndNote
Karamanlı H, Aygün F, Akgedik R (April 1, 2016) Relationship Between Severity of Obstructive Sleep Apnea and PR Interval. Koşuyolu Heart Journal 19 1 27–31.
IEEE
[1]H. Karamanlı, F. Aygün, and R. Akgedik, “Relationship Between Severity of Obstructive Sleep Apnea and PR Interval”, Koşuyolu Heart Journal, vol. 19, no. 1, pp. 27–31, Apr. 2016, [Online]. Available: https://izlik.org/JA57ZP37YY
ISNAD
Karamanlı, Harun - Aygün, Fatih - Akgedik, Recep. “Relationship Between Severity of Obstructive Sleep Apnea and PR Interval”. Koşuyolu Heart Journal 19/1 (April 1, 2016): 27-31. https://izlik.org/JA57ZP37YY.
JAMA
1.Karamanlı H, Aygün F, Akgedik R. Relationship Between Severity of Obstructive Sleep Apnea and PR Interval. Koşuyolu Heart Journal. 2016;19:27–31.
MLA
Karamanlı, Harun, et al. “Relationship Between Severity of Obstructive Sleep Apnea and PR Interval”. Koşuyolu Heart Journal, vol. 19, no. 1, Apr. 2016, pp. 27-31, https://izlik.org/JA57ZP37YY.
Vancouver
1.Harun Karamanlı, Fatih Aygün, Recep Akgedik. Relationship Between Severity of Obstructive Sleep Apnea and PR Interval. Koşuyolu Heart Journal [Internet]. 2016 Apr. 1;19(1):27-31. Available from: https://izlik.org/JA57ZP37YY