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            <front>

                <journal-meta>
                                                                <journal-id>ktd</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Kocatepe Tıp Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">3061-9904</issn>
                                                                                            <publisher>
                    <publisher-name>Afyonkarahisar Sağlık Bilimleri Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                                                                                                                                            <title-group>
                                                                                                                        <trans-title-group xml:lang="en">
                                    <trans-title>Sekretuar(Juvenil) Karsinom: Olgu Sunumu</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>Sekretuar(Juvenil) Karsinom: Olgu Sunumu</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Topak</surname>
                                    <given-names>Nevin</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Dilek</surname>
                                    <given-names>Fatma Hüsniye</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Sayar</surname>
                                    <given-names>Hamide</given-names>
                                </name>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname></surname>
                                    <given-names>Fatma Aktepe</given-names>
                                </name>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20060401">
                    <day>04</day>
                    <month>01</month>
                    <year>2006</year>
                </pub-date>
                                        <volume>7</volume>
                                        <issue>1</issue>
                                        <fpage>63</fpage>
                                        <lpage>65</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20150508">
                        <day>05</day>
                        <month>08</month>
                        <year>2015</year>
                    </date>
                                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1999, Kocatepe Tıp Dergisi</copyright-statement>
                    <copyright-year>1999</copyright-year>
                    <copyright-holder>Kocatepe Tıp Dergisi</copyright-holder>
                </permissions>
            
                                                                                                                        <abstract><p>Onaltı yaşında bir kız çocuğun sağ memesinde bulunan 4,5x3,5x3 cm boyutlarda kitle eksizyonel olarak çıkarıldı. Kitlenin makroskopik incelemesinde; çevreden çok iyi sınırlı, fakat kapsülsüz tümöral doku izlendi. Tümörün mikroskopik görüntüsü belirleyici olup, eozinofilik sekresyonla dolu lümen oluşturan eozinofilik, granüler veya berrak sitoplazmalı hücrelerle döşeli tubuloalveolar ve fokal papiller yapılar vardı. Hücrelerin bazılarında nukleus belirgin nukleol içermekteydi, mitoz nadir olarak izlendi. S-100 protein, östrojen ve progesteron reseptörü, poliklonal karsinoembriyojenik antijen (CEA) antikorları ile yapılan immunhistokimyasal boyamalarda S-100 ile pozitif reaktivite görüldü. Östrojen ve progesteron reseptörü, CEA ile pozitif reaktivite saptanmadı. Bu bulgularla olguya sekretuar karsinom tanısı verildi. Meme tümörlerinin nadir görülen tipi olan sekretuar karsinom, meme kanserlerinin %1’inden azını oluşturur. Prognozu çok iyidir ve bir çok seride 5 yıllık yaşam %100’e yakın olarak bildirilmektedir</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>meme kanseri</kwd>
                                                    <kwd>   juvenil kanser</kwd>
                                                    <kwd>   sekretuar kanser</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="en">
                                                    <kwd>-</kwd>
                                            </kwd-group>
                                                                                                                                        </article-meta>
    </front>
    <back>
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