ktd

Kocatepe Tıp Dergisi

3061-9904

Afyonkarahisar Sağlık Bilimleri Üniversitesi

10.18229/kocatepetip.474995

THE IMPORTANCE OF MORPHOLOGICAL-CLINICAL CONSISTENCY: THROUGH THE REVIEW OF GASTRIC BIOPSIES IN NORTH-EASTERN ANATOLIA REGION IN TURKEY

TÜRKİYE’DE KUZEY-DOĞU ANADOLU BÖLGESİNDEKİ MİDE BİYOPSİLERİNİN İNCELENMESİ İLE: MORFOLOJİK-KLİNİK UYUMUN ÖNEMİ

Demirtaş

Rabia

Erdoğan Durmuş

Şenay

Yarıkkaya

Enver

10 26 2018

19 4 135 138 08 18 2017 01 19 2018

1999

Kocatepe Tıp Dergisi

OBJECTIVE: In our study we aimed to make a generallyreview of gastric biyopsies in North-Eastern Anatoliaregion in Turkey such as; percentages of malignancy ordysplasia, reasons of re-biopsy recommendations andresults of second biopsies if taken.MATERIAL AND METHODS: 1840 gastric biopsies whichexamined by 3 pathologists at 2 centers were analyzedretrospectively. Percentages of malignancy or dysplasia,cases which were recommended for re-biopsies, reasonsof recommendations and results of re-biopsies wereexamined. In the results of the second biopsies, dysplasia,malignancy and gastritis were accepted as a significantresult.RESULTS: The mean age of our cases was 52.9 ± 16.6 years(range: 18-95 years). 1012 (55%) patients were femalesand 828 (45%) patients were males. In 90 out of 1840cases, biopsies were taken for suspect of malignancy,clinically. 35 of 90 cases were reported as malignancy. In61 out of 1840 cases re-biopsy were recommended. Reasonsof recommendations for re-biopsy categorized inthree groups: suspect of malignancy- clinically, suspectof malignancy- morphologically, insufficient (superficial)biopsies. 12 (46.2%) of 26 cases which were taken secondbiopsies were reported as malignancy and gastricdysplasia. Only in 2 (7.6%) of 26 cases the results wereinsignificant (insufficient biopsy).CONCLUSIONS: Endoscopic findings provide informationabout the diagnosis but are not pathognomonicwhich also need histological confirmation. Closeworking relationship and a good dialogue between thepathologist and the gastroenterologist is essential forclinical-morpological consistency, morphological-clinicalconsistency and final diagnosis.

AMAÇ: Çalışmamızda Türkiye'deki Kuzey-Doğu Anadolubölgesindeki gastrik biyopsileri genel olarak gözdengeçirmeyi amaçladık; malignite veya displazi yüzdeleri,biyopsi tekrarı önerilerinin nedenleri ve alınmışsa ikincibiyopsi sonuçları gibi.GEREÇ VE YÖNTEM: İki merkezde 3 patolog tarafındanincelenen 1840 gastrik biyopsi geriye dönük olarak incelendi.Malignite veya displazi yüzdeleri, biyopsi tekrarıönerilen vakalar, önerilerin nedenleri ve yeniden alınanbiyopsilerin sonuçları incelendi. İkinci biyopsi sonuçlarındadisplazi, malignite ve gastrit anlamlı sonuç olarakkabul edildi.BULGULAR: Olgularımızın yaş ortalaması 52.9 ± 16.6yıl (18-95 yıl) idi. 1012 hasta (% 55) kadın, 828 hasta (%45) erkekti. 1840 vakanın 90'ında, klinik olarak maligniteşüphesi için biyopsi alındı. Bu olguların 35'i maligniteolarak raporlandı. 1840 vakanın 61'ine biyopsi tekrarıönerildi. Yeniden biyopsi tavsiyelerinin sebeplerimalignite şüphesi - klinik, malignite şüphesi - morfolojikve yetersiz (yüzeyel) biyopsiler olarak üç gruba ayrıldı.İkinci biyopsi alınan 26 olgunun 12 'si (% 46.2) maligniteve gastrik displazi olarak bildirildi. 26 olgunun sadece2'sinde (% 7.6) sonuç anlamlı değildi (yetersiz biyopsi).SONUÇ: Endoskopik bulgular tanı hakkında bilgisağlarken, patognomonik değildir ve histolojik olarakonaylanması gerekir. Patolog ve gastroenterologarasındaki iyi bir diyalog ve yakın çalışma ilişkisi, klinikmorfolojiktutarlılık, morfolojik-klinik tutarlılık ve nihaiteşhis için önemlidir.

Gastric biopsies Malignancy biopsies

Gastrik biyopsiler Malignite Biyopsi tekrarı

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