DESIGN AND IMPLEMENTATION OF AN OFFLINE AUTOCLAVE WEB SIMULATOR

Abstract

This study presents a fully web-based, interactive simulator designed to facilitate understanding and training in autoclave sterilization processes, which are critical in healthcare and laboratory environments. Given the complexity of traditional theoretical training methods and the high costs and safety risks of using real equipment, digital simulation tools offer a crucial educational alternative. The simulator is a single-file application built with modern web technologies — HTML5, CSS3, and JavaScript — and requires no external installation or an internet connection. The core features of the simulator include real-time phase simulation, parameter adjustment with dynamic graphics, and interactive safety warnings for critical safety conditions. Users can experience all stages of the sterilization cycle (pre-vacuum, heating, sterilization, drying) and instantly observe how parameters such as temperature, time, and load type affect the process. In a pilot usability study conducted with 20 undergraduate students, more than 90% reported that the simulator improved their understanding of autoclave phases and safety protocols, highlighting its pedagogical effectiveness. Preliminary data and pilot feedback indicate that the interface is intuitive, understandable, and educationally beneficial. This digital tool demonstrates significant potential to reinforce theoretical knowledge and to prepare learners for practical applications, thereby addressing a critical gap in education.

Keywords

• Autoclave
• Digital Education
• Interactive Learning
• Sterilization
• Web-Based Simulator.

References

1. W. A. Rutala and D. J. Weber, "Disinfection and sterilization in health care facilities: An overview and current issues," Infectious Disease Clinics, vol. 35, no. 3, pp. 575–607, 2021, doi: 10.1016/j.idc.2021.04.004.
2. B. Bal and A. Balaraju, "Overview of the central sterilization supply department, an integral part of the hospital," Journal of Infection in Developing Countries, vol. 19, no. 3, pp. 325–334, 2025, doi: 10.3855/jidc.18646.
3. M. Davies, "Unwrapping the history of sterilisation," ACORN: The Journal of Perioperative Nursing in Australia, vol. 30, no. 4, pp. 41–46, 2017.
4. A. R. Talekar and A. G. Pise, "Systematic approach of autoclave qualification: A review," International Journal of Medical and Pharmaceutical Sciences, vol. 13, no. 9, pp. 1–6, 2023, doi: 10.31782/IJMPS.2023.13901.
5. T. Centea, L. K. Grunenfelder, and S. R. Nutt, "A review of out-of-autoclave prepregs–Material properties, process phenomena, and manufacturing considerations," Composites Part A: Applied Science and Manufacturing, vol. 70, pp. 132–154, 2015, doi: 10.1016/j.compositesa.2014.09.029.
6. P. DeSantis, "Steam sterilization in autoclaves," in Handbook of Validation in Pharmaceutical Processes, 4th ed. Boca Raton, FL, USA: CRC Press, 2021, pp. 217–230.
7. M. Kumaran, N. Fredrick, G. Dudeja, R. Sukumaran, and C. Dorairaj, "Steam sterilization: Review of autoclaves, validation, instrument packing, and sterility failures," Indian Journal of Ophthalmology, vol. 74, no. 2, pp. 173–182, 2026, doi: 10.4103/ijo.ijo_2023_25.
8. V. Antonucci et al., "Analysis of heat transfer in autoclave technology," Polymer Composites, vol. 22, no. 5, pp. 613–620, 2001, doi: 10.1002/pc.10564.

9. N. Vaclavovna Ronzhina, I. Mikhailovna Kondyurina, A. A. Voronina, K. A. Igishev, and N. A. Loginova, "Digitalization of modern education: Problems and solutions," International Journal of Emerging Technologies in Learning (iJET), vol. 16, no. 4, pp. 122-135, 2021, doi: 10.3991/ijet.v16i04.18203.
10. A. T. Bates, Technology, E-Learning and Distance Education. New York, NY, USA: Routledge, 2005.
11. A. Johnston, P. Hubert, G. Fernlund, R. Vaziri, and A. Poursartip, "Process modeling of composite structures employing a virtual autoclave concept," Science and Engineering of Composite Materials, vol. 5, no. 3–4, pp. 235–252, 1996, doi: 10.1515/SECM.1996.5.3-4.235.
12. D. C. Blest, S. McKee, A. K. Zulkifle, and P. Marshall, "Curing simulation by autoclave resin infusion," Composites Science and Technology, vol. 59, no. 16, pp. 2297–2313, 1999, doi: 10.1016/S0266-3538(99)00084-6.
13. B. Altinsu, O. Koçak, and A. Akpek, "Design and analysis of an autoclave simulation using MATLAB/Simulink," in Proc. 2016 Medical Technologies National Congress (TIPTEKNO), 2016, pp. 1–4, doi: 10.1109/TIPTEKNO.2016.7863081.
14. L. Angel, J. Viola, M. Vega, and R. Restrepo, "Sterilization process stages estimation for an autoclave using logistic regression models," in Proc. 2016 XXI Symposium on Signal Processing, Images and Artificial Vision (STSIVA), 2016, pp. 1–5, doi: 10.1109/STSIVA.2016.7743337.
15. A. Kaychenov, A. Vlasov, A. Maslov, I. Selyakov, and Y. Glukhikh, "Development of an autoclave thermal processes model for the simulator of canned food sterilization process," KnE Life Sciences, pp. 437–449, 2020, doi: 10.18502/kls.v5i1.6103.
16. J. He, F. Cong, M. Cao, X. Li, and S. Wang, "Finite element simulation of the autoclave curing process of aerospace resin-based composite material," IOP Conference Series: Earth and Environmental Science, vol. 693, no. 1, p. 012123, 2021, doi: 10.1088/1755-1315/693/1/012123.
17. B. Kou, Y. Hou, W. Fu, N. Yang, J. Liu, and G. Xie, "Simulation of multi-phase flow in autoclaves using a coupled CFD-DPM approach," Processes, vol. 11, no. 3, p. 890, 2023, doi: 10.3390/pr11030890.
18. S. Hoelle, F. Dengler, S. Zimmermann, and O. Hinrichsen, "3d thermal simulation of lithium-ion battery thermal runaway in autoclave calorimetry: Development and comparison of modeling approaches," Journal of The Electrochemical Society, vol. 170, no. 1, p. 010509, 2023, doi: 10.1149/1945-7111/acac06.
19. O. V. Radchuk, M. Y. Savchenko, S. V. Sokolov, and O. S. Sokolov, "Automation of a laboratory electric autoclave using a programmable logic controller," Journal of Chemistry and Technologies, vol. 33, no. 1, pp. 239–248, 2025, doi: 10.15421/jchemtech.v33i1.310425.
20. A. Garcia-Martinez, A. Fernandez-Jimenez, J. M. G. C. Sanchez, and A. J. Gutierrez-Trashorras, "Thermal effects of cooling dynamics in autoclave processing on composite materials," The International Journal of Advanced Manufacturing Technology, vol. 137, no. 5, pp. 2979–2989, 2025, doi: 10.1007/s00170-025-15346-9.
21. E. Caliani, M. Cavalcanti, L. M. F. Lona, and F. A. N. Fernandes, "Modeling and simulation of high-pressure industrial autoclave polyethylene reactor," Express Polymer Letters, vol. 2, no. 1, pp. 57–64, 2008, doi: 10.1016/S1570-7946(06)80117-3.
22. L. Boehler, M. Daniol, R. Sroka, D. Osinski, and A. Keller, "Sensors in the autoclave-modelling and implementation of the IoT steam sterilization procedure counter," Sensors, vol. 21, no. 2, p. 510, 2021, doi: 10.3390/s21020510.
23. A. Bakharia, K. Kitto, A. Pardo, D. Gašević, and S. Dawson, "Recipe for success: lessons learnt from using xAPI within the connected learning analytics toolkit," in Proc. 6th Int. Conf. Learning Analytics & Knowledge, 2016, pp. 378–382, doi: 10.1145/2883851.2883882.
24. F. B. García and A. H. Jorge, "Evaluating e-learning platforms through SCORM specifications," in Proc. IADIS Virtual Multi Conference on Computer Science and Information Systems, 2006, pp. 53–58.
25. B. Caldwell et al., "Web content accessibility guidelines (WCAG) 2.0," WWW Consortium (W3C), vol. 290, pp. 5–12, 2008.
26. J. Huang, "A simple accurate formula for calculating saturation vapor pressure of water and ice," Journal of Applied Meteorology and Climatology, vol. 57, no. 6, pp. 1265–1272, 2018, doi: 10.1175/JAMC-D-17-0334.1.
27. B. M. Boca, E. Pretorius, R. Gochin, R. Chapoullie, and Z. Apostolides, "An overview of the validation approach for moist heat sterilization, part II," Pharmaceutical Technology, vol. 26, no. 10, pp. 96–113, 2002.
28. C. V. Fiorello, C. A. Harms, S. K. Chinnadurai, and D. Strahl-Heldreth, "Best-practice guidelines for field-based surgery and anesthesia on free-ranging wildlife. II. Surgery," Journal of Wildlife Diseases, vol. 52, no. 2s, pp. S28–S39, 2016, doi: 10.7589/52.2S.S28.
29. N. Han, L. An, L. Fan, L. Hua, and G. Gao, "Research on temperature field distribution in a frame mold during autoclave process," Materials, vol. 13, no. 18, p. 4020, 2020, doi: 10.3390/ma13184020.
30. M. Fernández-Gracía, J. F. Sánchez-Pérez, F. del Cerro, and M. Conesa, "Mathematical Model to Calculate Heat Transfer in Cylindrical Vessels with Temperature-Dependent Materials," Axioms, vol. 12, no. 4, p. 335, 2023, doi: 10.3390/axioms12040335.
31. Y. Kaya, R. Günay, and F. K. Damgacı, "Kirkpatrick dört düzey program değerlendirme modeli," Uluslararası Eğitim Bilimleri Dergisi, no. 5, pp. 89–97, 2015.
32. R. Ibrahim et al., "E-learning acceptance based on technology acceptance model (TAM)," Journal of Fundamental and Applied Sciences, vol. 9, no. 4S, pp. 871–889, 2017, doi: 10.4314/jfas.v9i4s.50.