Polikistik Over Sendromu'nda Gözlenen Biyokimyasal Bozukluklar

Yıl 2011, Cilt: 3 Sayı: 1, 42 - 48, 01.04.2011

Ak Yıldırım H

Öz

Polikistik Over Sendromu reproduktif dönemdeki kadınların %510’unda görülmektedir. Çok sayıda klinik, laboratuar ve deneysel verilere rağmen hala patofizyolojisi hakkında tereddütler vardır. Polikistik steroidogenez bozukluğu, intraovarian faktörler, insülin rezistansı ve hiperinsülinemi, obezite, genetik faktörler, anormal granüloza hücreleri, enzimatik defektler gibi birkaç sistemin bozuk çalışmasının sinerjistik etkisi sonucu ortaya çıkan, multifaktöriyel bir hastalık olarak düşünülebilir. Bu derlemede bu konuların araştırılması amaçlanmıştır

Anahtar Kelimeler

Polikistik Over Sendromu, insülin rezistansı

Kaynakça

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