Hypo- versus hyper-thyroidism in 2 cats: the culprit for miliary dermatitis/hypersensitivity versus growth retardation

Abstract

In the present case series 2 different cats with diagnosis of hypo- versus hyper-thyroidism with distinct clinical signs were reported. The first case was a 3-month-old male domestic short-hair kitten was presented with a disproportionate dwarfism. Radiographic examination of the long bones revealed epiphyseal dysgenesis and delayed epiphyseal ossification. Congenital primary hypothyroidism was established by low serum total thyroxine. Initial treatment composed of levothyroxine. The second case was referred to the clinic with unresolved dermatological problems. On referral alopecia, extensive crusting and matting of the haircoat were evident. Hyperthyroidism and related military dermatitis was detected based on elevated serum total thyroxine and free T4 levels along with skin punch biopsy results. Therapeutical armamentarium composed of methimazole and hyperimmune milk factor. Early recognition, diagnosis and treatment intervention all resulted in clinical remission and relief of clinical signs accompanied by normal thyroidal function and laboratory results in both cats.

Keywords

• cat,dermatitis,dwarfism,hypothyroidism,hyperthyroidism

Hipotiroidizme karşı hipertiroidizm: İki kedide büyüme geriliğine karşı miliyer dermatitis/hipersensitivite

Abstract

Bu olgu sunumunda iki farklı kedide karşılaşılan hipotiroidizme karşı hipertiroidizm ilişkili farklı klinik bulgular sunuldu. İlk olgumuz 3 aylık yaşta, erkek, short-hair ırkı yavru kedi olup aşırı cücelik şikayeti ile kliniğimize getirilmiştir. Radyografik bulgularında uzun kemiklerde epifiziyal disgenezis ve epifiziyal kemikleşmede geçikme tespit edildi. Kongenital hipotiroidzm tanısı düşük total tiroksin seviyesiyle desteklendi ve levotiroksin ile sağaltıma başlanıldı. İkinci olgumuz ise sağaltıma ragmen düzelmeyen dermatolojik bulgular ile kliniğimize başvurdu. Klinik muayenede alopesi, yaygın kabuklanma ve kıl örtüsünde matlaşma görüldü. Deriden alınan punç biyopsi sonuçları, artan serum total tiroksin ve serbest T4 ve ilişkili miliyar dermatitis ile hipertiroidizm tanısı konuldu. Bu olgumuzda metimazol ve hiperimmun süt faktörü başlanıldı. Sonuç olarak her iki olgumuzda da erken tanı ve sağaltım ilişkili klinik bulguların giderilmesine ve laboratuvar sonuçlarına göre normal tiroid fonksiyonlarına kavuşmalarına yol açtı.

Keywords

• cücelik,dermatitis,hipotiroidizm,hipertiroidizm,kedi

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