makufebed Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi 1309-2243 Burdur Mehmet Akif Ersoy Üniversitesi 10.29048/makufebed.1727930 Nanomaterials Nanomalzemeler Tenebrio molitor L. Türüne Karşı Sentetik Böcek İlaçlarına Biyouyumlu Bir Alternatif Olarak Katyonik PVA (CPVA)’nın Değerlendirilmesi Evaluation of Cationic PVA (CPVA) as a Biocompatible Alternative to Synthetic Insecticides Against Tenebrio molitor L. https://orcid.org/0000-0002-4026-1358 Üstündağ Gökçe ZONGULDAK BÜLENT ECEVİT ÜNİVERSİTESİ https://orcid.org/0000-0001-7733-2263 Şen Ferhat ZONGULDAK BULENT ECEVIT UNİVERSİTESİ https://orcid.org/0000-0002-2115-8339 Zor Mustafa ZONGULDAK BULENT ECEVIT UNİVERSİTESİ 12 29 2025 16 2 53 59 06 26 2025 08 29 2025 Copyright © 2010, Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi 2010 Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi

Tenebrio molitor L., tahıl ve un gibi gıda maddelerinin depolandığı alanlarda önemli kayıplara yol açan bir zararlıdır. Tarımsal ürünlerin depolandığı dünyanın birçok ülkesinde bu zararlının neden olduğu istilalar, kontamine ürünlerde %20’ye varan hasara yol açabilmektedir. Bu zararlılarla mücadelede çevreye ve faydalı organizmalara olumsuz etkileri olan sentetik organik insektisitler yaygın olarak kullanılmaktadır. Bu nedenle, T. molitor’un kontrolü için toksik olmayan veya çevreye daha az zararlı kimyasal alternatiflerin geliştirilmesi büyük önem taşımaktadır. Bu çalışmada, toksik olmayan CPVA bileşiğinin, insektisitlere alternatif bir ajan olarak kullanılabilirliği, model organizma olarak T. molitor kullanılarak araştırılmıştır. Bu amaçla, PVA katyonize edilerek CPVA sentezlenmiştir. Laboratuvar koşullarında T. molitor larvaları üzerinde CPVA’nın farklı konsantrasyonları (%5, %20, %40, %60 ve %80) test edilmiştir. CPVA’nın zararlının larval gelişimi, davranış değişiklikleri ve genel fizyolojik tepkiler üzerindeki etkileri analiz edilerek çevresel güvenlik profiline dair ön bulgular elde edilmiştir. Elde edilen sonuçlar, CPVA’nın entomolojik biyoteknoloji alanında, özellikle alternatif pestisit stratejileri ve gıda/yem güvenliği uygulamaları açısından potansiyel taşıdığını göstermektedir.

Tenebrio molitor L. is a pest that causes significant losses in storage areas of food such as grains and flour. In countries around the world where agricultural products are stored, infestations can lead to damage of up to 20% in contaminated products. Synthetic organic insecticides, which have negative effects on the environment and beneficial organisms, are widely used to control these pests. Therefore, it is of great importance to develop non-toxic or less environmentally harmful chemical alternatives for controlling T. molitor. In this study, the potential of the non-toxic CPVA compound to serve as an alternative agent to insecticides was investigated using T. molitor as a model organism. For this purpose, PVA was cationized to synthesize CPVA. CPVA at different concentrations (5%, 20%, 40%, 60%, and 80%) was tested against T. molitor larvae under laboratory conditions. Preliminary insights into its environmental safety profile were obtained by analyzing CPVA's effects on larval development, behavioral changes, and general physiological responses. The results indicated potential applications of CPVA in entomological biotechnology, particularly for alternative pesticide strategies and food/feed safety.

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