Research Article
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Rhythms and risks: Examining the relationship between circadian patterns and nicotine and alcohol use among medical students

Year 2026, Volume: 39 Issue: 1, 73 - 79, 28.01.2026
https://doi.org/10.5472/marumj.1873572

Abstract

Objective: Chronotype refers to an individual’s natural preference for sleep and wake times, which reflects their internal circadian
rhythm. It determines whether a person feels more alert and active in the morning, in the evening, or follows a more intermediate
pattern. The aim of the study was to identify a potential association between chronotypes and the consumption of nicotine and highrisk
alcohol use among medical students.
Materials and Methods: The study was conducted between May 2024 and June 2024 via an online platform (Google Forms) among
medical students in Marmara University. Horne-Ostberg’s Morningness-Eveningness Questionnaire form was used to determine the
circadian rhythm characteristics. Univariate and multivariate analyses were performed to determine the associations of nicotine and
high-risk alcohol use with chronotype.
Results: A total of 323 medical students participated in the survey. Of the respondents, 198 (61.3%) had an intermediate chronotype,
69 (21.4%) had a morning chronotype, and 56 (17.3%) had an evening chronotype. It was observed that students with an evening
chronotype had a statistically significantly higher rate of regular nicotine use compared to those with a morning chronotype (OR=3.62,
p=0.04) and a high-risk alcohol use (OR=4.49, p=0.015).
Conclusion: Assessing the evening type population among medical students may be a specific target for educational health promotion
interventions aimed at preventing or reducing alcohol and nicotine consumption.

References

  • Waterhouse J. Introduction to chronobiology. In: Abacıoğlu N, Zengil H, editors. Fundamentals of Chronobiology and Chronotherapy. Ankara (Turkiye): Palme Publishing; 1999.
  • Weaver DR. The suprachiasmatic nucleus: a 25- year retrospective. J Biol Rhythms 1998;13:100-12. doi:10.1177/074873098128999952.
  • Duffy JF, Rimmer DW, Czeisler CA. Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase. Behav Neurosci 2001;115:895-9. doi:10.1037/0735-7044.115.4.895.
  • Edgar RS, Green EW, Zhao Y, et al. Peroxiredoxins are conserved markers of circadian rhythms. Nature 2012;485(7399):459-64. doi:10.1038/nature11088.
  • Aschoff J, Gerecke U, Wever R. Desynchronization of human circadian rhythms. Jpn J Physiol 1967;17:450-7. doi:10.2170/ jjphysiol.17.450.
  • Kerkhof GA. Inter-individual differences in the human circadian system: a review. Biol Psychol 1985;20:83-112. doi:10.1016/0301-0511(85)90019-5.
  • Roenneberg T, Wirz-Justice A, Merrow M. Life between clocks: daily temporal patterns of human chronotypes. J Biol Rhythms 2003;18:80-90. doi:10.1177/0748730402239679.
  • Adan A, Archer SN, Hidalgo MP, Di Milia L, Natale V, Randler C. Circadian typology: a comprehensive review. Chronobiol Int 2012;29:1153-75. doi:10.3109/07420528.2012.719971.
  • Mecacci L, Rocchetti G. Morning and evening types: stressrelated personality aspects. Pers Individ Dif 1998;25:537-42. doi:10.1016/S0191-8869(98)00087-7.
  • Fabbian F, Zucchi B, De Giorgi A, et al. Chronotype, gender and general health. Chronobiol Int 2016;33:863-82. doi:10.108 0/07420528.2016.1176927.
  • Schneider ML, Vasconcellos DC, Dantas G, et al. Morningnesseveningness, use of stimulants, and minor psychiatric disorders among undergraduate students. Int J Psychol 2011;46:18-23. doi:10.1080/00207594.2010.513414.
  • Prat G, Adan A. Influence of circadian typology on drug consumption, hazardous alcohol use, and hangover symptoms. Chronobiol Int 2011;28:248-57. doi:10.3109/07420.528.2011.5 53018.
  • Van den Berg JF, Kivelä L, Antypa N. Chronotype and depressive symptoms in students: an investigation of possible mechanisms. Chronobiol Int 2018;35:1248-61. doi:10.1080/07 420528.2018.1470531.
  • Horne JA, Ostberg O. A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms Int J Chronobiol 1976;4:97-110
  • Pündük Z, Gür H, Ercan I. Sabahçıl-Akşamcıl Anketi Türkçe uyarlamasında güvenilirlik çalışması [A reliability study of the Turkish version of the mornings-evenings questionnaire]. Turk Psikiyatri Derg 2005;16:40-5.
  • World Health Organization, U.S. Centers for Disease Control and Prevention. Tobacco Questions for Surveys of Youth (TQS-Youth): A Subset of Key Questions from the Global Youth Tobacco Survey (GYTS). Geneva: World Health Organization; 2019. Licence: CC BY-NC-SA 3.0 IGO.
  • Cetin E, Cantürk N, Dağalp R. Alcohol Scale: Validity and reliability study in cigarette addict students. Journal of Dependence 2019;20:72-9.
  • Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grand M. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption – II. Addiction 1993;88: 791-804.
  • Johnston LD, O’Malley PM, Bachman JG, Schulenberg JE. Monitoring the future national survey results on drug use, 1975–2003. Volume II: College Students and Adults Ages 19– 45. Bethesda (MD): National Institute on Drug Abuse; 2004. NIH Publication No. 04–5508.
  • Picton A, Greenfield S, Parry J. Why do students struggle in their first year of medical school? A qualitative study of student voices. BMC Med Educ 2022;22(1):100. doi: 10.1186/ s12909-022-03158-4.
  • Tanriover O, Peker S, Hidiroglu S, et al. The emotions experienced by family medicine residents and interns during their clinical trainings: a qualitative study. Prim Health Care Res Dev 2023;24:e25. doi:10.1017/S1463423623000051.
  • Chinwong D, Mookmanee N, Chongpornchai J, Chinwong S. A comparison of gender differences in smoking behaviors, ıntention to quit, and nicotine dependence among thai university students. J Addict 2018;2018:8081670. doi: 10.1155/2018/8081670.
  • Schwarzbold ML, Haas GM, Barni RS, et al. At-risk drinking and current cannabis use among medical students: a multivariable analysis of the role of personality traits. Braz J Psychiatry 2020;42:136-44. doi:10.1590/1516-4446-2018- 0318.
  • Freire BR, Castro PASV, Petroianu A. Alcohol consumption by medical students. Rev Assoc Med Bras (1992) 2020;66:943-7. doi:10.1590/1806-9282.66.7.943.
  • Siudej K, Malinowska-Borowska J. Relationship between chronotype and consumption of stimulants. Chronobiol Int 2021;38:1549-56. doi:10.1080/07420528.2021.1935989.
  • Sirtoli R, Mata GDG, Rodrigues R, et al. Is evening chronotype associated with higher alcohol consumption? A systematic review and meta-analysis. Chronobiol Int 2023;40:1467-79. doi:10.1080/07420528.2023.2256899.
  • Giannotti F, Cortesi F, Sebastiani T, Ottaviano S. Circadian preference, sleep and daytime behaviour in adolescence. J Sleep Res 2002;11:191-9. doi:10.1046/j.1365-2869.2002.00302.x.
  • Urbán R, Magyaródi T, Rigó A. Morningness-eveningness, chronotypes and health-impairing behaviors in adolescents. Chronobiol Int 2011;28:238-47. doi:10.3109/07420528.2010. 549599.
  • Evans SL, Norbury R. Associations between diurnal preference, impulsivity and substance use in a young-adult student sample. Chronobiol Int 2021;38:79-89. doi:10.1080/07 420528.2020.1810063.
  • Wang L, Chartrand TL. Morningness–eveningness and risk taking. J Psychol 2015;149:394-411. doi:10.1080/00223980.2 014.885874.
  • Caci H, Robert P, Boyer P. Novelty seekers and impulsive subjects are low in morningness. Eur Psychiatry 2004;19:79- 84. doi:10.1016/j.eurpsy.2003.09.007.
  • Foulds JA, Boden JM, Newton-Howes GM, Mulder RT, Horwood LJ. The role of novelty seeking as a predictor of substance use disorder outcomes in early adulthood. Addiction 2017;112:1629-37. doi:10.1111/add.13838.
  • Hisler GC, Rothenberger SD, Clark DB, Hasler BP. Is there a 24-hour rhythm in alcohol craving and does it vary by sleep/ circadian timing? Chronobiol Int 2021;38:109-21. doi:10.1080 /07420528.2020.1838532.
  • Wittmann M, Paulus M, Roenneberg T. Decreased psychological well-being in late ‘chronotypes’ is mediated by smoking and alcohol consumption. Subst Use Misuse 2010;45:15-30. doi:10.3109/10826080903498952.
  • Zhang Y, Liu D, Sheng L, et al. Chronotype and sleep duration are associated with stimulant consumption and BMI among Chinese undergraduates. Sleep Biol Rhythms 2018;16:211-22. doi:10.1007/s41105.017.0142-6.
  • Wittmann M, Dinich J, Merrow M, Roenneberg T. Social jetlag: misalignment of biological and social time. Chronobiol Int 2006;23:497-509. doi:10.1080/07420520500545979.
  • Adan A, Natale V. Gender differences in morningnesseveningness preference. Chronobiol Int 2002;19:709-20. doi:10.1081/CBI-120005390.
  • Danielsson K, Sakarya A, Jansson-Fröjmark M. The reduced morningness–eveningness questionnaire: psychometric properties and related factors in a young Swedish population. Chronobiol Int 2019;36:530-40. doi:10.1080/07420528.2018.1 564322.
  • Carrier J, Monk TH, Buysse DJ, Kupfer DJ. Sleep and morningness-eveningness in the ‘middle’ years of life (20-59 y). J Sleep Res. 1997;6:230-7. doi:10.1111/j.1365- 2869.1997.00230.x.
  • Adan A, Almirall H. Horne & Östberg morningnesseveningness questionnaire: a reduced scale. Pers Individ Dif 1991;12:241-53. doi:10.1016/0191-8869(91)90110-W.

Year 2026, Volume: 39 Issue: 1, 73 - 79, 28.01.2026
https://doi.org/10.5472/marumj.1873572

Abstract

References

  • Waterhouse J. Introduction to chronobiology. In: Abacıoğlu N, Zengil H, editors. Fundamentals of Chronobiology and Chronotherapy. Ankara (Turkiye): Palme Publishing; 1999.
  • Weaver DR. The suprachiasmatic nucleus: a 25- year retrospective. J Biol Rhythms 1998;13:100-12. doi:10.1177/074873098128999952.
  • Duffy JF, Rimmer DW, Czeisler CA. Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase. Behav Neurosci 2001;115:895-9. doi:10.1037/0735-7044.115.4.895.
  • Edgar RS, Green EW, Zhao Y, et al. Peroxiredoxins are conserved markers of circadian rhythms. Nature 2012;485(7399):459-64. doi:10.1038/nature11088.
  • Aschoff J, Gerecke U, Wever R. Desynchronization of human circadian rhythms. Jpn J Physiol 1967;17:450-7. doi:10.2170/ jjphysiol.17.450.
  • Kerkhof GA. Inter-individual differences in the human circadian system: a review. Biol Psychol 1985;20:83-112. doi:10.1016/0301-0511(85)90019-5.
  • Roenneberg T, Wirz-Justice A, Merrow M. Life between clocks: daily temporal patterns of human chronotypes. J Biol Rhythms 2003;18:80-90. doi:10.1177/0748730402239679.
  • Adan A, Archer SN, Hidalgo MP, Di Milia L, Natale V, Randler C. Circadian typology: a comprehensive review. Chronobiol Int 2012;29:1153-75. doi:10.3109/07420528.2012.719971.
  • Mecacci L, Rocchetti G. Morning and evening types: stressrelated personality aspects. Pers Individ Dif 1998;25:537-42. doi:10.1016/S0191-8869(98)00087-7.
  • Fabbian F, Zucchi B, De Giorgi A, et al. Chronotype, gender and general health. Chronobiol Int 2016;33:863-82. doi:10.108 0/07420528.2016.1176927.
  • Schneider ML, Vasconcellos DC, Dantas G, et al. Morningnesseveningness, use of stimulants, and minor psychiatric disorders among undergraduate students. Int J Psychol 2011;46:18-23. doi:10.1080/00207594.2010.513414.
  • Prat G, Adan A. Influence of circadian typology on drug consumption, hazardous alcohol use, and hangover symptoms. Chronobiol Int 2011;28:248-57. doi:10.3109/07420.528.2011.5 53018.
  • Van den Berg JF, Kivelä L, Antypa N. Chronotype and depressive symptoms in students: an investigation of possible mechanisms. Chronobiol Int 2018;35:1248-61. doi:10.1080/07 420528.2018.1470531.
  • Horne JA, Ostberg O. A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms Int J Chronobiol 1976;4:97-110
  • Pündük Z, Gür H, Ercan I. Sabahçıl-Akşamcıl Anketi Türkçe uyarlamasında güvenilirlik çalışması [A reliability study of the Turkish version of the mornings-evenings questionnaire]. Turk Psikiyatri Derg 2005;16:40-5.
  • World Health Organization, U.S. Centers for Disease Control and Prevention. Tobacco Questions for Surveys of Youth (TQS-Youth): A Subset of Key Questions from the Global Youth Tobacco Survey (GYTS). Geneva: World Health Organization; 2019. Licence: CC BY-NC-SA 3.0 IGO.
  • Cetin E, Cantürk N, Dağalp R. Alcohol Scale: Validity and reliability study in cigarette addict students. Journal of Dependence 2019;20:72-9.
  • Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grand M. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption – II. Addiction 1993;88: 791-804.
  • Johnston LD, O’Malley PM, Bachman JG, Schulenberg JE. Monitoring the future national survey results on drug use, 1975–2003. Volume II: College Students and Adults Ages 19– 45. Bethesda (MD): National Institute on Drug Abuse; 2004. NIH Publication No. 04–5508.
  • Picton A, Greenfield S, Parry J. Why do students struggle in their first year of medical school? A qualitative study of student voices. BMC Med Educ 2022;22(1):100. doi: 10.1186/ s12909-022-03158-4.
  • Tanriover O, Peker S, Hidiroglu S, et al. The emotions experienced by family medicine residents and interns during their clinical trainings: a qualitative study. Prim Health Care Res Dev 2023;24:e25. doi:10.1017/S1463423623000051.
  • Chinwong D, Mookmanee N, Chongpornchai J, Chinwong S. A comparison of gender differences in smoking behaviors, ıntention to quit, and nicotine dependence among thai university students. J Addict 2018;2018:8081670. doi: 10.1155/2018/8081670.
  • Schwarzbold ML, Haas GM, Barni RS, et al. At-risk drinking and current cannabis use among medical students: a multivariable analysis of the role of personality traits. Braz J Psychiatry 2020;42:136-44. doi:10.1590/1516-4446-2018- 0318.
  • Freire BR, Castro PASV, Petroianu A. Alcohol consumption by medical students. Rev Assoc Med Bras (1992) 2020;66:943-7. doi:10.1590/1806-9282.66.7.943.
  • Siudej K, Malinowska-Borowska J. Relationship between chronotype and consumption of stimulants. Chronobiol Int 2021;38:1549-56. doi:10.1080/07420528.2021.1935989.
  • Sirtoli R, Mata GDG, Rodrigues R, et al. Is evening chronotype associated with higher alcohol consumption? A systematic review and meta-analysis. Chronobiol Int 2023;40:1467-79. doi:10.1080/07420528.2023.2256899.
  • Giannotti F, Cortesi F, Sebastiani T, Ottaviano S. Circadian preference, sleep and daytime behaviour in adolescence. J Sleep Res 2002;11:191-9. doi:10.1046/j.1365-2869.2002.00302.x.
  • Urbán R, Magyaródi T, Rigó A. Morningness-eveningness, chronotypes and health-impairing behaviors in adolescents. Chronobiol Int 2011;28:238-47. doi:10.3109/07420528.2010. 549599.
  • Evans SL, Norbury R. Associations between diurnal preference, impulsivity and substance use in a young-adult student sample. Chronobiol Int 2021;38:79-89. doi:10.1080/07 420528.2020.1810063.
  • Wang L, Chartrand TL. Morningness–eveningness and risk taking. J Psychol 2015;149:394-411. doi:10.1080/00223980.2 014.885874.
  • Caci H, Robert P, Boyer P. Novelty seekers and impulsive subjects are low in morningness. Eur Psychiatry 2004;19:79- 84. doi:10.1016/j.eurpsy.2003.09.007.
  • Foulds JA, Boden JM, Newton-Howes GM, Mulder RT, Horwood LJ. The role of novelty seeking as a predictor of substance use disorder outcomes in early adulthood. Addiction 2017;112:1629-37. doi:10.1111/add.13838.
  • Hisler GC, Rothenberger SD, Clark DB, Hasler BP. Is there a 24-hour rhythm in alcohol craving and does it vary by sleep/ circadian timing? Chronobiol Int 2021;38:109-21. doi:10.1080 /07420528.2020.1838532.
  • Wittmann M, Paulus M, Roenneberg T. Decreased psychological well-being in late ‘chronotypes’ is mediated by smoking and alcohol consumption. Subst Use Misuse 2010;45:15-30. doi:10.3109/10826080903498952.
  • Zhang Y, Liu D, Sheng L, et al. Chronotype and sleep duration are associated with stimulant consumption and BMI among Chinese undergraduates. Sleep Biol Rhythms 2018;16:211-22. doi:10.1007/s41105.017.0142-6.
  • Wittmann M, Dinich J, Merrow M, Roenneberg T. Social jetlag: misalignment of biological and social time. Chronobiol Int 2006;23:497-509. doi:10.1080/07420520500545979.
  • Adan A, Natale V. Gender differences in morningnesseveningness preference. Chronobiol Int 2002;19:709-20. doi:10.1081/CBI-120005390.
  • Danielsson K, Sakarya A, Jansson-Fröjmark M. The reduced morningness–eveningness questionnaire: psychometric properties and related factors in a young Swedish population. Chronobiol Int 2019;36:530-40. doi:10.1080/07420528.2018.1 564322.
  • Carrier J, Monk TH, Buysse DJ, Kupfer DJ. Sleep and morningness-eveningness in the ‘middle’ years of life (20-59 y). J Sleep Res. 1997;6:230-7. doi:10.1111/j.1365- 2869.1997.00230.x.
  • Adan A, Almirall H. Horne & Östberg morningnesseveningness questionnaire: a reduced scale. Pers Individ Dif 1991;12:241-53. doi:10.1016/0191-8869(91)90110-W.
There are 40 citations in total.

Details

Primary Language English
Subjects Surgery (Other)
Journal Section Research Article
Authors

Özlem Tanrıöver 0000-0003-0251-3451

Seyhan Hıdıroğlu 0000-0001-8656-4613

Mahmut Batman 0000-0003-4344-6910

Aslihan Sayar This is me

Aliye Caglar This is me

Esma Gundag This is me

Cagin Bora Cesmeli This is me

Zeynep Ozturk This is me

Deniz Yalcinbayir

Pınar Ay

Submission Date March 26, 2025
Acceptance Date December 31, 2025
Publication Date January 28, 2026
Published in Issue Year 2026 Volume: 39 Issue: 1

Cite

APA Tanrıöver, Ö., Hıdıroğlu, S., Batman, M., Sayar, A., Caglar, A., Gundag, E., Cesmeli, C. B., Ozturk, Z., Yalcinbayir, D., & Ay, P. (2026). Rhythms and risks: Examining the relationship between circadian patterns and nicotine and alcohol use among medical students. Marmara Medical Journal, 39(1), 73-79. https://doi.org/10.5472/marumj.1873572
AMA 1.Tanrıöver Ö, Hıdıroğlu S, Batman M, et al. Rhythms and risks: Examining the relationship between circadian patterns and nicotine and alcohol use among medical students. Marmara Med J. 2026;39(1):73-79. doi:10.5472/marumj.1873572
Chicago Tanrıöver, Özlem, Seyhan Hıdıroğlu, Mahmut Batman, et al. 2026. “Rhythms and Risks: Examining the Relationship Between Circadian Patterns and Nicotine and Alcohol Use Among Medical Students”. Marmara Medical Journal 39 (1): 73-79. https://doi.org/10.5472/marumj.1873572.
EndNote Tanrıöver Ö, Hıdıroğlu S, Batman M, Sayar A, Caglar A, Gundag E, Cesmeli CB, Ozturk Z, Yalcinbayir D, Ay P (January 1, 2026) Rhythms and risks: Examining the relationship between circadian patterns and nicotine and alcohol use among medical students. Marmara Medical Journal 39 1 73–79.
IEEE [1]Ö. Tanrıöver et al., “Rhythms and risks: Examining the relationship between circadian patterns and nicotine and alcohol use among medical students”, Marmara Med J, vol. 39, no. 1, pp. 73–79, Jan. 2026, doi: 10.5472/marumj.1873572.
ISNAD Tanrıöver, Özlem - Hıdıroğlu, Seyhan - Batman, Mahmut - Sayar, Aslihan - Caglar, Aliye - Gundag, Esma - Cesmeli, Cagin Bora - Ozturk, Zeynep - Yalcinbayir, Deniz - Ay, Pınar. “Rhythms and Risks: Examining the Relationship Between Circadian Patterns and Nicotine and Alcohol Use Among Medical Students”. Marmara Medical Journal 39/1 (January 1, 2026): 73-79. https://doi.org/10.5472/marumj.1873572.
JAMA 1.Tanrıöver Ö, Hıdıroğlu S, Batman M, Sayar A, Caglar A, Gundag E, Cesmeli CB, Ozturk Z, Yalcinbayir D, Ay P. Rhythms and risks: Examining the relationship between circadian patterns and nicotine and alcohol use among medical students. Marmara Med J. 2026;39:73–79.
MLA Tanrıöver, Özlem, et al. “Rhythms and Risks: Examining the Relationship Between Circadian Patterns and Nicotine and Alcohol Use Among Medical Students”. Marmara Medical Journal, vol. 39, no. 1, Jan. 2026, pp. 73-79, doi:10.5472/marumj.1873572.
Vancouver 1.Tanrıöver Ö, Hıdıroğlu S, Batman M, Sayar A, Caglar A, Gundag E, et al. Rhythms and risks: Examining the relationship between circadian patterns and nicotine and alcohol use among medical students. Marmara Med J [Internet]. 2026 Jan. 1;39(1):73-9. Available from: https://izlik.org/JA76AG47CJ