Fallopian tube metastasis in a patient with a history of breast cancer

Abstract

Breast carcinoma metastasis to the fallopian tube is extremely

rare. Distinction between a primary fallopian tumor and metastasis

of breast cancer is crucial since treatment and prognosis are

different. However, it is difficult to confirm pathologically without

surgery. Herein, we report a 46-year-old woman with a history

of left modified radical mastectomy for breast cancer 13 years

ago, presenting with a left adnexial mass. She underwent total

abdominal hysterectomy with bilateral salpingo-oophorectomy.

Pathology findings revealed cytokeratin (CK) 7, ER, and PR

positive tumor cells. Mammoglobuline, P53, CK20, GCDFP-15

and, thrombomoduline were negative. HER2 was also 2+.

Fluorescence in situ hybridization (FISH) for HER2 was negative.

Based on the morphology and immunophenotype of the tumor,

we established the diagnosis as metastasis of breast cancer to the

fallopian tube.

Keywords

• Fallopian tube cancer,Breast cancer,Fallopian tube metastasis

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