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Endothelial cells are active

Yıl 1992, Cilt: 5 Sayı: 2, 83 - 87, 01.04.1992

Öz

The vascular endothelium was long regarded as simply a diffusion barrier, but now it is recognized that endothelium is a metabolically active mediator of interactions between blood and underlying smooth muscle. Metabolic functions of endothelial cells include the enzymatic destruction of serotonin, norepinephrine, the conversion of angiotensin I to potent vasoconstrictor angiotensin II and the breakdown of potent vasodilator bradyki- nin. Endothelial cells also synthesize and secrete vasodilator and antiaggregant prostacyclin and endothelium derived relaxing factor. These cells are normally non- thrombogenic and unstimulated platelets do not adhere to the surface but when the cells are injured platelets adhere to the exposed subendothelium. Coagulation can be initiated by damaged endothelial cells because they bind coagulation factors and may activate them. Endothelium can control coagulation by activation of anticoagulant protein C and by increasing the affinity of antithrombin III for thrombin. Endothelial cells contribute to the process of fibrinolysis by synthesizing plasminogen activators and plasminogen activator inhibitors.

Kaynakça

  • Manuscripts, letters and editorial correspondence should be sent to 'Editor. Marmara Medical Journal. Marmara University. Faculty of Medicine. Istanbul-Turkey' by first class mail (airmail for overseas).
Yıl 1992, Cilt: 5 Sayı: 2, 83 - 87, 01.04.1992

Öz

Kaynakça

  • Manuscripts, letters and editorial correspondence should be sent to 'Editor. Marmara Medical Journal. Marmara University. Faculty of Medicine. Istanbul-Turkey' by first class mail (airmail for overseas).
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Konular Klinik Tıp Bilimleri
Bölüm Reviews
Yazarlar

S. Bilsel Bu kişi benim

K. Emerk Bu kişi benim

Yayımlanma Tarihi 1 Nisan 1992
Yayımlandığı Sayı Yıl 1992 Cilt: 5 Sayı: 2

Kaynak Göster

APA Bilsel, S., & Emerk, K. (1992). Endothelial cells are active. Marmara Medical Journal, 5(2), 83-87.
AMA Bilsel S, Emerk K. Endothelial cells are active. Marmara Med J. Nisan 1992;5(2):83-87.
Chicago Bilsel, S., ve K. Emerk. “Endothelial Cells Are Active”. Marmara Medical Journal 5, sy. 2 (Nisan 1992): 83-87.
EndNote Bilsel S, Emerk K (01 Nisan 1992) Endothelial cells are active. Marmara Medical Journal 5 2 83–87.
IEEE S. Bilsel ve K. Emerk, “Endothelial cells are active”, Marmara Med J, c. 5, sy. 2, ss. 83–87, 1992.
ISNAD Bilsel, S. - Emerk, K. “Endothelial Cells Are Active”. Marmara Medical Journal 5/2 (Nisan 1992), 83-87.
JAMA Bilsel S, Emerk K. Endothelial cells are active. Marmara Med J. 1992;5:83–87.
MLA Bilsel, S. ve K. Emerk. “Endothelial Cells Are Active”. Marmara Medical Journal, c. 5, sy. 2, 1992, ss. 83-87.
Vancouver Bilsel S, Emerk K. Endothelial cells are active. Marmara Med J. 1992;5(2):83-7.