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Comparison of the efficacy of lisuride versus bromocriptine in the treatment of hyperprolactinemia

Year 1994, Volume: 7 Issue: 1, 10 - 13, 01.01.1994

M. Erenus M. Kır L.C. Kutlay S. Pekin

Abstract

Dopamine agonists have been succesfully used in the treatment of various clinical disorders associated with hyperprolactinemia. However all of them are associated with some side effects which differ in incidence and severity. We have compared the efficacy and side effects of lisuride with bromocriptine in the treatment of hyperprolactinemia.

Twenty women with hyperprolactinemia were randomized to receive either oral lisuride or bromocriptine. Ten patients received lisuride 0.2 mg b.i.d. and other ten received bromocriptine 2.5 mg b.i.d. All of the patients were evaluated with computerized tomography for the presence of pituitary adenoma. Fasting blood samples were obtained weekly for four weeks and patients were asked to note the side effects. Both lisuride and bromocriptine decreased baseline prolactin values significantly by the fourth week of the treatment. The incidence of side effects were similiar in both groups.

As a result, lisuride is found to be as effective as bromocriptine in the treatment of hyperprolactinemia with comparable side effects.

Keywords

Lisuride Hyperprolactinemia Bromocriptine

References

  • De Ceccol. Venturini PL, Ragni M. Valenzano M, Oustantini S, Horwski R. Dopaminergic ergots in lactation and cycle disturbances. In: Caine, DB et al. eds. Lisuride and other dopamine agonists. Raven Press:Hew York, 1983:291-299.

Year 1994, Volume: 7 Issue: 1, 10 - 13, 01.01.1994

M. Erenus M. Kır L.C. Kutlay S. Pekin

Abstract

References

  • De Ceccol. Venturini PL, Ragni M. Valenzano M, Oustantini S, Horwski R. Dopaminergic ergots in lactation and cycle disturbances. In: Caine, DB et al. eds. Lisuride and other dopamine agonists. Raven Press:Hew York, 1983:291-299.
There are 1 citations in total.

Details

Subjects Clinical Sciences
Journal Section Review Makaleler
Authors

M. Erenus This is me

M. Kır This is me

L.C. Kutlay This is me

S. Pekin This is me

Publication Date January 1, 1994
Published in Issue Year 1994 Volume: 7 Issue: 1

Cite

APA Erenus, M., Kır, M., Kutlay, L., Pekin, S. (1994). Comparison of the efficacy of lisuride versus bromocriptine in the treatment of hyperprolactinemia. Marmara Medical Journal, 7(1), 10-13.
AMA Erenus M, Kır M, Kutlay L, Pekin S. Comparison of the efficacy of lisuride versus bromocriptine in the treatment of hyperprolactinemia. Marmara Med J. January 1994;7(1):10-13.
Chicago Erenus, M., M. Kır, L.C. Kutlay, and S. Pekin. “Comparison of the Efficacy of Lisuride Versus Bromocriptine in the Treatment of Hyperprolactinemia”. Marmara Medical Journal 7, no. 1 (January 1994): 10-13.
EndNote Erenus M, Kır M, Kutlay L, Pekin S (January 1, 1994) Comparison of the efficacy of lisuride versus bromocriptine in the treatment of hyperprolactinemia. Marmara Medical Journal 7 1 10–13.
IEEE M. Erenus, M. Kır, L. Kutlay, and S. Pekin, “Comparison of the efficacy of lisuride versus bromocriptine in the treatment of hyperprolactinemia”, Marmara Med J, vol. 7, no. 1, pp. 10–13, 1994.
ISNAD Erenus, M. et al. “Comparison of the Efficacy of Lisuride Versus Bromocriptine in the Treatment of Hyperprolactinemia”. Marmara Medical Journal 7/1 (January 1994), 10-13.
JAMA Erenus M, Kır M, Kutlay L, Pekin S. Comparison of the efficacy of lisuride versus bromocriptine in the treatment of hyperprolactinemia. Marmara Med J. 1994;7:10–13.
MLA Erenus, M. et al. “Comparison of the Efficacy of Lisuride Versus Bromocriptine in the Treatment of Hyperprolactinemia”. Marmara Medical Journal, vol. 7, no. 1, 1994, pp. 10-13.
Vancouver Erenus M, Kır M, Kutlay L, Pekin S. Comparison of the efficacy of lisuride versus bromocriptine in the treatment of hyperprolactinemia. Marmara Med J. 1994;7(1):10-3.