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Nasopharyngeal carriage rate and antimicrobial resistance of haemophilus influenzae in İstanbul - Turkiye

Year 1994, Volume: 7 Issue: 2, 78 - 80, 01.04.1994

M.h. Vahaboğlu L. Mülazimoğlu İ. Yıldırım V. Avkan B. Taşer

Abstract

We prospectively studied 462 individuals of different age groups attending to outpatient clinics in Istanbul to assess the nasopharyngeal colonization rate and the antibiotic resistance patterns of the isolated haemophilus strains. Prevalence of Haemophilus influenzae in patients under 5 years of age and in patients over 5 years of age was 76.9% (253/329) and 58.6%(78/133), respectively. The antimicrobial susceptibility to chloramphenicol, ampicillin, cefuroxime and ceftriaxone was determined by microbroth dilution tests. Of 106 H. influenzae isolates, 24.5% were resistant to ampicillin, 8.5% to both ampicillin and cephalosporins, and 4.7% to all four antibiotics. Twenty point eight percent of the strains produced beta-lactamase. These results emphasize the emerging resistance to ampicillin among H. influenzae strains in Turkiye and urge to discuss efficacy of the first line agents in H. infections.

Keywords

Haemophilus Ampicillin Cefuroxime Ceftriaxone Chloramphenicol

References

  • Thomas WJ, McReynolds JW. Mock CR, Bailey DW. Ampicillin-resistant Haemophilus influenzae meningitis. Lancet 1974, (ii):311.

Year 1994, Volume: 7 Issue: 2, 78 - 80, 01.04.1994

M.h. Vahaboğlu L. Mülazimoğlu İ. Yıldırım V. Avkan B. Taşer

Abstract

References

  • Thomas WJ, McReynolds JW. Mock CR, Bailey DW. Ampicillin-resistant Haemophilus influenzae meningitis. Lancet 1974, (ii):311.
There are 1 citations in total.

Details

Subjects Clinical Sciences
Journal Section Review Makaleler
Authors

M.h. Vahaboğlu This is me

L. Mülazimoğlu This is me

İ. Yıldırım This is me

V. Avkan This is me

B. Taşer This is me

Publication Date April 1, 1994
Published in Issue Year 1994 Volume: 7 Issue: 2

Cite

APA Vahaboğlu, M., Mülazimoğlu, L., Yıldırım, İ., Avkan, V., et al. (1994). Nasopharyngeal carriage rate and antimicrobial resistance of haemophilus influenzae in İstanbul - Turkiye. Marmara Medical Journal, 7(2), 78-80.
AMA Vahaboğlu M, Mülazimoğlu L, Yıldırım İ, Avkan V, Taşer B. Nasopharyngeal carriage rate and antimicrobial resistance of haemophilus influenzae in İstanbul - Turkiye. Marmara Med J. April 1994;7(2):78-80.
Chicago Vahaboğlu, M.h., L. Mülazimoğlu, İ. Yıldırım, V. Avkan, and B. Taşer. “Nasopharyngeal Carriage Rate and Antimicrobial Resistance of Haemophilus Influenzae in İstanbul - Turkiye”. Marmara Medical Journal 7, no. 2 (April 1994): 78-80.
EndNote Vahaboğlu M, Mülazimoğlu L, Yıldırım İ, Avkan V, Taşer B (April 1, 1994) Nasopharyngeal carriage rate and antimicrobial resistance of haemophilus influenzae in İstanbul - Turkiye. Marmara Medical Journal 7 2 78–80.
IEEE M. Vahaboğlu, L. Mülazimoğlu, İ. Yıldırım, V. Avkan, and B. Taşer, “Nasopharyngeal carriage rate and antimicrobial resistance of haemophilus influenzae in İstanbul - Turkiye”, Marmara Med J, vol. 7, no. 2, pp. 78–80, 1994.
ISNAD Vahaboğlu, M.h. et al. “Nasopharyngeal Carriage Rate and Antimicrobial Resistance of Haemophilus Influenzae in İstanbul - Turkiye”. Marmara Medical Journal 7/2 (April 1994), 78-80.
JAMA Vahaboğlu M, Mülazimoğlu L, Yıldırım İ, Avkan V, Taşer B. Nasopharyngeal carriage rate and antimicrobial resistance of haemophilus influenzae in İstanbul - Turkiye. Marmara Med J. 1994;7:78–80.
MLA Vahaboğlu, M.h. et al. “Nasopharyngeal Carriage Rate and Antimicrobial Resistance of Haemophilus Influenzae in İstanbul - Turkiye”. Marmara Medical Journal, vol. 7, no. 2, 1994, pp. 78-80.
Vancouver Vahaboğlu M, Mülazimoğlu L, Yıldırım İ, Avkan V, Taşer B. Nasopharyngeal carriage rate and antimicrobial resistance of haemophilus influenzae in İstanbul - Turkiye. Marmara Med J. 1994;7(2):78-80.