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Chemiluminescence in the measurement of free radicals: Theory and application on a tissue injury model

Year 1998, Volume: 11 Issue: 1, 56 - 60, 01.01.1998

Abstract

Reactive oxygen species have been implicated in the pathogenesis of several human diseases. However, it is difficult to quantitate reactive oxygen metabolites because of their reactive nature and short half lives. Instead, analyses of secondary or end products produced by the attack of free radicals on lipids, proteins or other cellular components are preferred. These indirect methods usually give misleading results due to their poor specificity and sensitivity. Chemiluminescence (CL) is the production of light generated from chemical sources. It may be utilized as a direct noninvasive method for measuring reactive oxygen species. Different probes with different selectivities can be used in CL measurements. The use of CL measurements in quantitating free radical reactions, advantages over other methods and its applications on a tissue injury model will be presented.

References

  • Halliwell B, Gutteridge JMC, eds. Free Radicals in Biology and Medicine. Oxford University Press, 1989.
Year 1998, Volume: 11 Issue: 1, 56 - 60, 01.01.1998

Abstract

References

  • Halliwell B, Gutteridge JMC, eds. Free Radicals in Biology and Medicine. Oxford University Press, 1989.
There are 1 citations in total.

Details

Subjects Clinical Sciences
Journal Section Review Makaleler
Authors

G. Haklar This is me

M. Yüksel This is me

A. S. Yalçın This is me

Publication Date January 1, 1998
Published in Issue Year 1998 Volume: 11 Issue: 1

Cite

APA Haklar, G., Yüksel, M., & Yalçın, A. S. (1998). Chemiluminescence in the measurement of free radicals: Theory and application on a tissue injury model. Marmara Medical Journal, 11(1), 56-60.
AMA Haklar G, Yüksel M, Yalçın AS. Chemiluminescence in the measurement of free radicals: Theory and application on a tissue injury model. Marmara Med J. January 1998;11(1):56-60.
Chicago Haklar, G., M. Yüksel, and A. S. Yalçın. “Chemiluminescence in the Measurement of Free Radicals: Theory and Application on a Tissue Injury Model”. Marmara Medical Journal 11, no. 1 (January 1998): 56-60.
EndNote Haklar G, Yüksel M, Yalçın AS (January 1, 1998) Chemiluminescence in the measurement of free radicals: Theory and application on a tissue injury model. Marmara Medical Journal 11 1 56–60.
IEEE G. Haklar, M. Yüksel, and A. S. Yalçın, “Chemiluminescence in the measurement of free radicals: Theory and application on a tissue injury model”, Marmara Med J, vol. 11, no. 1, pp. 56–60, 1998.
ISNAD Haklar, G. et al. “Chemiluminescence in the Measurement of Free Radicals: Theory and Application on a Tissue Injury Model”. Marmara Medical Journal 11/1 (January 1998), 56-60.
JAMA Haklar G, Yüksel M, Yalçın AS. Chemiluminescence in the measurement of free radicals: Theory and application on a tissue injury model. Marmara Med J. 1998;11:56–60.
MLA Haklar, G. et al. “Chemiluminescence in the Measurement of Free Radicals: Theory and Application on a Tissue Injury Model”. Marmara Medical Journal, vol. 11, no. 1, 1998, pp. 56-60.
Vancouver Haklar G, Yüksel M, Yalçın AS. Chemiluminescence in the measurement of free radicals: Theory and application on a tissue injury model. Marmara Med J. 1998;11(1):56-60.