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PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS

Year 1999, Volume: 12 Issue: 1, 29 - 32, 03.12.2016

Aymelek Yalın Serap Arbak Feriha Ercan

Abstract

Objective: The aim of this study was to investigate time-related ultrastructural alterations in the rat liver during Euro-Collins perfusion and storage.
Material-Methods: Rat liver pieces were placed in cold (4°C) Euro-Collins solution and stored for 0, 3, 6 and 12 hour periods. Morphologic investigations were performed using electron microscopy.
Results: Electronmicrographs from the 3 hour and 6 hour perfusions showed a slight degree of hepatocellular degeneration. Extremely swollen and degenerated hepatocytes were observed at the 12th hour of preservation period.
Conclusion: It is concluded that the safe storage period for the rat liver in Euro-Collins solution is less than 12 hours.
Key Words: Liver, tissue preservation, Euro- Collins solution, ultrastructure

References

  • Bergstrom U ti, Patk O P, Tufveson G, Wahl berg J. Up to 22 hour preservation of small bowel using a transplantation model in the pig. Trans Proceedings 1990; 22:135-136.
  • Hooper TL, Thomson DS. Jones MT et al. Amelioration of lung ischaemic injury with prostacyclin. Transplantation 1990;49:1031-1035.
  • Michel A, Vons C, Hillaire S, et al. Comparison of rat liver preservation with Euro-Collins and a modified University of Wisconsin solution: Transplantation and isolation of hepatocytes for culture. Eur Surg Res 1990; 22: 249-255.
  • Morishita Y, Moriyama Y, Ikoma A et al. Technique for procurement of heart, liver and kidneys from a single donor for transplantation. J Cardiovas Surg 1990; 32: 46-49.
  • Okamura R, Mu rase H, Kim SO, Todo S, Ozawa K, Starzi T E. Fluorometric study of the viability of rat liver grafts after simple cold storage with UW solution versus Euro-Collins solution. Transplant Proceed 1991; 23: 1877-1881.
  • Pruim J, ten Verged E M, Klompmaker I J, Verwer R, Sloof M J H. Cellular damage and early metabolic function of transplanted livers stored in Euro-Collins or University of Wisconsin solution. Eur Surg Res 1991; 23: 285-291.
  • Todo S, Hery J, Yanaga K, Podesta L, Gordon RD. Extended preservation of human liver grafts with UW solution. JAMA 1989; 261:711-715.
  • Schmid T, Landry O, Fields BL, Belzer FO, Hawodh RA, Southard JH et al. The use of monocytes as a
  • model for developing successful head preservation solutions. Transplantation 1991; 52: 20-24.
  • Toledo L H, Bergren C T. Liver preservation techniques for transplantation. Adificial organs 1987; 11:214-223.
  • Yalin A, Gürsoy E. Ultrastructural observations on hypothermic preservation of canine kidney. Tr J of Medical Sciences 1994; 20:215-220.
  • Kshettry VR, Kroshus TJ, Burdine J, Savik K, Bolmon RM. Does donor organ ischaemia over four hours affect long-term survival after lung transplantation? J Head Lung Transplant. 1996;15:169-174,
  • Lehtola A, Harjula A, Heikkila L, et al. Single lung allotransplantation in pigs: a morphologic study of tissue preservation with modified Euro-Collins and fluorocarbon solutions. Transplantation 1990; 49:1066-1074.
  • Lin PJ, Hsieh MJ, Cheng KS, Kuo TT, Chang CH. University of Wisconsin solution extends lung preservation after prostaglandin EI infusion. Chest 1994; 105: 255-261.
  • Myagkaya GL, Veeon HA, James J. Ultrastructural changes in the rat liver during Euro-Collins storage, compared with hypothermic in vitro ischaemia. Virchows Arch B 1987; 53:176-182.
  • Snell G I, Rabinov M, Griffiths A, Williams T, Ugoni A, Salamonsson R .Esmore D. Pulmonary allograft ischaemic time: an impodant predictor of survival after lung transplantation. J Head Lung Transplant 1996; 15:160-168.
  • Wu G, Zhang F, Salley RK, Robinson MC, Chien S. A systematic study of hypothermic lung preservation solutions: Euro-Collins solution. Ann Thorac Surg 1996; 62:356-362.
  • I 7. Collins GM, Bravo-Sugerman M, Terasaki PL Kidney preparation for transpodation: initial perfusion and 30 hours cold ice storage. Lancet 1969; 22-1219- 1223.
  • Olthoff KM, Millis JM, Imagawa DK, et al. Comparison of UW solution and Euro-collins for cold preservation of human liver grafts. Transplantation 1990; 49: 284-290
  • Momii S, Koga A. Time-related morphological changes in cold-stored rat livers. Transplantation 1990; 50:745-750
  • Caldwell-Kenkel JC, Currin RT, Tanaka Y, Thurman RG, Lemasters JJ. Kupffer cell activation and endothelial cell damage after storage of rat livers: Effects of reperfusion. Hepatology 1990; 13 (I): 83- 95
  • Junqueira LC, Carneiro J. Kelley RO. The cell. In: Basic histology. Sixth ed. California, Appleton and Lange, 1989:28-52.

Year 1999, Volume: 12 Issue: 1, 29 - 32, 03.12.2016

Aymelek Yalın Serap Arbak Feriha Ercan

Abstract

References

  • Bergstrom U ti, Patk O P, Tufveson G, Wahl berg J. Up to 22 hour preservation of small bowel using a transplantation model in the pig. Trans Proceedings 1990; 22:135-136.
  • Hooper TL, Thomson DS. Jones MT et al. Amelioration of lung ischaemic injury with prostacyclin. Transplantation 1990;49:1031-1035.
  • Michel A, Vons C, Hillaire S, et al. Comparison of rat liver preservation with Euro-Collins and a modified University of Wisconsin solution: Transplantation and isolation of hepatocytes for culture. Eur Surg Res 1990; 22: 249-255.
  • Morishita Y, Moriyama Y, Ikoma A et al. Technique for procurement of heart, liver and kidneys from a single donor for transplantation. J Cardiovas Surg 1990; 32: 46-49.
  • Okamura R, Mu rase H, Kim SO, Todo S, Ozawa K, Starzi T E. Fluorometric study of the viability of rat liver grafts after simple cold storage with UW solution versus Euro-Collins solution. Transplant Proceed 1991; 23: 1877-1881.
  • Pruim J, ten Verged E M, Klompmaker I J, Verwer R, Sloof M J H. Cellular damage and early metabolic function of transplanted livers stored in Euro-Collins or University of Wisconsin solution. Eur Surg Res 1991; 23: 285-291.
  • Todo S, Hery J, Yanaga K, Podesta L, Gordon RD. Extended preservation of human liver grafts with UW solution. JAMA 1989; 261:711-715.
  • Schmid T, Landry O, Fields BL, Belzer FO, Hawodh RA, Southard JH et al. The use of monocytes as a
  • model for developing successful head preservation solutions. Transplantation 1991; 52: 20-24.
  • Toledo L H, Bergren C T. Liver preservation techniques for transplantation. Adificial organs 1987; 11:214-223.
  • Yalin A, Gürsoy E. Ultrastructural observations on hypothermic preservation of canine kidney. Tr J of Medical Sciences 1994; 20:215-220.
  • Kshettry VR, Kroshus TJ, Burdine J, Savik K, Bolmon RM. Does donor organ ischaemia over four hours affect long-term survival after lung transplantation? J Head Lung Transplant. 1996;15:169-174,
  • Lehtola A, Harjula A, Heikkila L, et al. Single lung allotransplantation in pigs: a morphologic study of tissue preservation with modified Euro-Collins and fluorocarbon solutions. Transplantation 1990; 49:1066-1074.
  • Lin PJ, Hsieh MJ, Cheng KS, Kuo TT, Chang CH. University of Wisconsin solution extends lung preservation after prostaglandin EI infusion. Chest 1994; 105: 255-261.
  • Myagkaya GL, Veeon HA, James J. Ultrastructural changes in the rat liver during Euro-Collins storage, compared with hypothermic in vitro ischaemia. Virchows Arch B 1987; 53:176-182.
  • Snell G I, Rabinov M, Griffiths A, Williams T, Ugoni A, Salamonsson R .Esmore D. Pulmonary allograft ischaemic time: an impodant predictor of survival after lung transplantation. J Head Lung Transplant 1996; 15:160-168.
  • Wu G, Zhang F, Salley RK, Robinson MC, Chien S. A systematic study of hypothermic lung preservation solutions: Euro-Collins solution. Ann Thorac Surg 1996; 62:356-362.
  • I 7. Collins GM, Bravo-Sugerman M, Terasaki PL Kidney preparation for transpodation: initial perfusion and 30 hours cold ice storage. Lancet 1969; 22-1219- 1223.
  • Olthoff KM, Millis JM, Imagawa DK, et al. Comparison of UW solution and Euro-collins for cold preservation of human liver grafts. Transplantation 1990; 49: 284-290
  • Momii S, Koga A. Time-related morphological changes in cold-stored rat livers. Transplantation 1990; 50:745-750
  • Caldwell-Kenkel JC, Currin RT, Tanaka Y, Thurman RG, Lemasters JJ. Kupffer cell activation and endothelial cell damage after storage of rat livers: Effects of reperfusion. Hepatology 1990; 13 (I): 83- 95
  • Junqueira LC, Carneiro J. Kelley RO. The cell. In: Basic histology. Sixth ed. California, Appleton and Lange, 1989:28-52.
There are 22 citations in total.

Details

Journal Section Original Research
Authors

Aymelek Yalın This is me

Serap Arbak This is me

Feriha Ercan This is me

Publication Date December 3, 2016
Published in Issue Year 1999 Volume: 12 Issue: 1

Cite

APA Yalın, A., Arbak, S., & Ercan, F. (2016). PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS. Marmara Medical Journal, 12(1), 29-32.
AMA Yalın A, Arbak S, Ercan F. PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS. Marmara Med J. June 2016;12(1):29-32.
Chicago Yalın, Aymelek, Serap Arbak, and Feriha Ercan. “PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS”. Marmara Medical Journal 12, no. 1 (June 2016): 29-32.
EndNote Yalın A, Arbak S, Ercan F (June 1, 2016) PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS. Marmara Medical Journal 12 1 29–32.
IEEE A. Yalın, S. Arbak, and F. Ercan, “PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS”, Marmara Med J, vol. 12, no. 1, pp. 29–32, 2016.
ISNAD Yalın, Aymelek et al. “PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS”. Marmara Medical Journal 12/1 (June 2016), 29-32.
JAMA Yalın A, Arbak S, Ercan F. PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS. Marmara Med J. 2016;12:29–32.
MLA Yalın, Aymelek et al. “PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS”. Marmara Medical Journal, vol. 12, no. 1, 2016, pp. 29-32.
Vancouver Yalın A, Arbak S, Ercan F. PRESERVATION OF LIVER WITH EURO-COLLINS SOLUTION: EVALUATION OF ULTRASTRUCTURAL ALTERATIONS. Marmara Med J. 2016;12(1):29-32.