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INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION

Year 2001, Volume: 14 Issue: 4, 255 - 258, 03.12.2016

Abstract

Alzheimer’s Disease (AD) is a progressive disease involving the loss of several cognitive functions. In the etiology there are mutation deficits in some genes and resultant mutational changes in amyloid precursor protein, presenilin 1 and 2, apolipoprotein E and low-density- lipoprotein-bound receptor protein (1).

References

  • Victor M, Ropper AH. Degenerative diseases of the nervous system. In: Adam's and Victor's Principles of neurology. 7th ed. USA: McGrawHill, 2001:1114-1116.
  • Grutzendler J, Morris JC. Cholinesterase inhibitors for Alzheimer's disease. Drugs 2001:61;41-52.
  • Kaplan H, Sadock B. Dementia. In: Kaplan and Sadock's Synopsis of Psychiatry. Middle East ed., 8th ed. Giza - Egypt: Wiliams & Wilkins, ¡998:328-345.
  • World Health Organization. The ICD-IO Classification of Mental and Behavioural Disorders. World Health Organization, Genova, 1992,
  • Delirium, dementia, and amnestic and other cognitive disorders. In: The Task Force on DSM-IV and other committees and work groups of manual of mental disorders: DSM- IV. 4th ed. American Psychiatric Association, Washington, DC, 1994:123-163.
  • McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the ITinCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease, neurology 1984:34; 939-944.
  • Kumral E, Acarer A. Alzheimer hastalığında tanı kriterleri ve genel klinik özellikler. İn: Alzheimer Hastalığı, Kutay FZ, ed. İzmir: Ege University Press, 2000:1-18.
  • Çağrı Yalgın, et al
  • Zurad EG. new treatments of Alzheimer disease: a review. Drug Benefit Trends 2001: 13:27-40.
  • Terry RD, Masliah E, Hansen LA. Structural basis of the cognitive alteration in Alzheimer's disease. In: Terry RD, Ratzman R, Bick RL, eds. Alzheimer Disease. Raven Press, Hew York, 1994:179-196.
  • Ratzman R. Alzheimer's disease, n Eng J Pled 1986:363:964-973.
  • Rozemuiier JM. neuropathology of dementias.
  • Syllabus 2001, The Amsterdam International Medical Summer School, "Bridging neurology 8c Psychiatry: Dementia, Depression,
  • Schizophrenia and Addiction". July 15-28, 2001, Amsterdam, the netherlands.
  • Sezer C, Mem iş L. Alzheimer hastalığı histopatolojisi. Demans Dergisi 2001:1:42-49.
  • Rutay FZ. Alzheimer hastalığının
  • etyopatogenezindeki biyokimyasal
  • mekanizmalar. In: Alzheimer Hastalığı, Rutay FZ, ed. İzmir: Ege University Press, 2000:19- 51.
  • Lewis J, Dickson DW, Lin WL et al. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 2001:293:1487-1491.
  • Götz J, Chen F, van Dorpe J, Tiitsch RM. Formation of neurofibrillay tangles in P301L tau transgenic mice induced by Ap42 fibrils. Science 2001 -.293; 1491-1495.
  • McGieenon BM, Dynan RB, Passmore AP. Acetylcholinesterase inhibitors in Alzheimer's disease. Br J Clin Pharmacol 1999:48:471- 480.
  • Benzi G, Moretti A. Is there a rationale for the use of acetylcholinesterase inhibitors in the therapy of Alzheimer's disease? Eur J Pharmacol 1998:346; 1-13.
  • Guillozet AL, Smiley JF, Mash DC, et al. Butyrylcholinesterase in the life cycle of amyloid plaques. Ann Heurol 1997:42:909- 918.
  • Wright Cl, Geula C, Mesulam MM. neurological cholinesterases in the normal brain and Alzheimer's disease: relationship to plaques, tangles, and patterns of selective vulnerability. Ann Heurol 1993:34;3 73-384.
  • Rosen WG, Mohs RC, Davis RL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984:141,1356-1364.
  • Berg L, Miller JP, Baty J, et al. Mild senide dementia of the Alzheimer type. 4. Evaluation of intervention. Ann Heurol 1992:31 ;242- 249.
  • Madden S, Spaldin V, Park BR. Clinical pharmacokinetics of tacrine. Clin Pharmacokinet 1995:28:449-45 7.
  • Farlow M, Gracon SI, Hershey LA, et al. A controlled trial of tacrine in Alzheimer's disease. The Tacrine Study Group. JAMA 1992:268:2523-2529.
  • Rnapp MJ, Rnopman DS, Soloman PR, et al. A 30-week randomized controlled trial of lilgh- dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group. JAMA 1994:271:985-991.
  • Farlow MR, Lahiri DR, Poirier J, et al. Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease. Heurology 1998:50:669-677.
  • Rogers SL, Fried ho ff LT. Pharmacokinetic and pharmacodynamic profile of donepezil HCI following single oral doses. Br J Clin Pharmacol 1998:46 Suppl I: 1-6.
  • The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicentre, randomized, double-blind placebo-controlled trial. The Donepezil Study Group. Dementia 1996:7:293-303.
  • Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group. Heurology 1998:50; 136-145.
  • Corey-Bloom J, Anand R, Veach J. A randomized trial evaluating the efficacy and safety of EHA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. The EHA 713 B352 Study Group. Int J Geriatr Psychopharmacol 1998:1 ;55-65.
  • Rosier M, Anand R, Cicin-Sain A, et al. Efficacy
  • and safety of rivastigmine in patients with Alzheimer's disease: international
  • randomised controlled trial. Br Med J 1999: 318:633-640.
  • Raskind MA, Peskind ER, Wessel T. Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group. Heurology 2000:54:2261 -2268.
  • Tariot PH, Solomon PR, Morris JC, et al. A 5- month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA- 10 Study Group. Heurology 2000:54:2269- 2276.
Year 2001, Volume: 14 Issue: 4, 255 - 258, 03.12.2016

Abstract

References

  • Victor M, Ropper AH. Degenerative diseases of the nervous system. In: Adam's and Victor's Principles of neurology. 7th ed. USA: McGrawHill, 2001:1114-1116.
  • Grutzendler J, Morris JC. Cholinesterase inhibitors for Alzheimer's disease. Drugs 2001:61;41-52.
  • Kaplan H, Sadock B. Dementia. In: Kaplan and Sadock's Synopsis of Psychiatry. Middle East ed., 8th ed. Giza - Egypt: Wiliams & Wilkins, ¡998:328-345.
  • World Health Organization. The ICD-IO Classification of Mental and Behavioural Disorders. World Health Organization, Genova, 1992,
  • Delirium, dementia, and amnestic and other cognitive disorders. In: The Task Force on DSM-IV and other committees and work groups of manual of mental disorders: DSM- IV. 4th ed. American Psychiatric Association, Washington, DC, 1994:123-163.
  • McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the ITinCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease, neurology 1984:34; 939-944.
  • Kumral E, Acarer A. Alzheimer hastalığında tanı kriterleri ve genel klinik özellikler. İn: Alzheimer Hastalığı, Kutay FZ, ed. İzmir: Ege University Press, 2000:1-18.
  • Çağrı Yalgın, et al
  • Zurad EG. new treatments of Alzheimer disease: a review. Drug Benefit Trends 2001: 13:27-40.
  • Terry RD, Masliah E, Hansen LA. Structural basis of the cognitive alteration in Alzheimer's disease. In: Terry RD, Ratzman R, Bick RL, eds. Alzheimer Disease. Raven Press, Hew York, 1994:179-196.
  • Ratzman R. Alzheimer's disease, n Eng J Pled 1986:363:964-973.
  • Rozemuiier JM. neuropathology of dementias.
  • Syllabus 2001, The Amsterdam International Medical Summer School, "Bridging neurology 8c Psychiatry: Dementia, Depression,
  • Schizophrenia and Addiction". July 15-28, 2001, Amsterdam, the netherlands.
  • Sezer C, Mem iş L. Alzheimer hastalığı histopatolojisi. Demans Dergisi 2001:1:42-49.
  • Rutay FZ. Alzheimer hastalığının
  • etyopatogenezindeki biyokimyasal
  • mekanizmalar. In: Alzheimer Hastalığı, Rutay FZ, ed. İzmir: Ege University Press, 2000:19- 51.
  • Lewis J, Dickson DW, Lin WL et al. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 2001:293:1487-1491.
  • Götz J, Chen F, van Dorpe J, Tiitsch RM. Formation of neurofibrillay tangles in P301L tau transgenic mice induced by Ap42 fibrils. Science 2001 -.293; 1491-1495.
  • McGieenon BM, Dynan RB, Passmore AP. Acetylcholinesterase inhibitors in Alzheimer's disease. Br J Clin Pharmacol 1999:48:471- 480.
  • Benzi G, Moretti A. Is there a rationale for the use of acetylcholinesterase inhibitors in the therapy of Alzheimer's disease? Eur J Pharmacol 1998:346; 1-13.
  • Guillozet AL, Smiley JF, Mash DC, et al. Butyrylcholinesterase in the life cycle of amyloid plaques. Ann Heurol 1997:42:909- 918.
  • Wright Cl, Geula C, Mesulam MM. neurological cholinesterases in the normal brain and Alzheimer's disease: relationship to plaques, tangles, and patterns of selective vulnerability. Ann Heurol 1993:34;3 73-384.
  • Rosen WG, Mohs RC, Davis RL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984:141,1356-1364.
  • Berg L, Miller JP, Baty J, et al. Mild senide dementia of the Alzheimer type. 4. Evaluation of intervention. Ann Heurol 1992:31 ;242- 249.
  • Madden S, Spaldin V, Park BR. Clinical pharmacokinetics of tacrine. Clin Pharmacokinet 1995:28:449-45 7.
  • Farlow M, Gracon SI, Hershey LA, et al. A controlled trial of tacrine in Alzheimer's disease. The Tacrine Study Group. JAMA 1992:268:2523-2529.
  • Rnapp MJ, Rnopman DS, Soloman PR, et al. A 30-week randomized controlled trial of lilgh- dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group. JAMA 1994:271:985-991.
  • Farlow MR, Lahiri DR, Poirier J, et al. Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease. Heurology 1998:50:669-677.
  • Rogers SL, Fried ho ff LT. Pharmacokinetic and pharmacodynamic profile of donepezil HCI following single oral doses. Br J Clin Pharmacol 1998:46 Suppl I: 1-6.
  • The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicentre, randomized, double-blind placebo-controlled trial. The Donepezil Study Group. Dementia 1996:7:293-303.
  • Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group. Heurology 1998:50; 136-145.
  • Corey-Bloom J, Anand R, Veach J. A randomized trial evaluating the efficacy and safety of EHA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. The EHA 713 B352 Study Group. Int J Geriatr Psychopharmacol 1998:1 ;55-65.
  • Rosier M, Anand R, Cicin-Sain A, et al. Efficacy
  • and safety of rivastigmine in patients with Alzheimer's disease: international
  • randomised controlled trial. Br Med J 1999: 318:633-640.
  • Raskind MA, Peskind ER, Wessel T. Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group. Heurology 2000:54:2261 -2268.
  • Tariot PH, Solomon PR, Morris JC, et al. A 5- month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA- 10 Study Group. Heurology 2000:54:2269- 2276.
There are 39 citations in total.

Details

Journal Section Medical Education
Authors

Çağrı Kalaca This is me

Ahmet Arzık This is me

Sibel Kalaca This is me

Pemra Ünalan This is me

Publication Date December 3, 2016
Published in Issue Year 2001 Volume: 14 Issue: 4

Cite

APA Kalaca, Ç., Arzık, A., Kalaca, S., Ünalan, P. (2016). INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION. Marmara Medical Journal, 14(4), 255-258.
AMA Kalaca Ç, Arzık A, Kalaca S, Ünalan P. INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION. Marmara Med J. June 2016;14(4):255-258.
Chicago Kalaca, Çağrı, Ahmet Arzık, Sibel Kalaca, and Pemra Ünalan. “INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION”. Marmara Medical Journal 14, no. 4 (June 2016): 255-58.
EndNote Kalaca Ç, Arzık A, Kalaca S, Ünalan P (June 1, 2016) INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION. Marmara Medical Journal 14 4 255–258.
IEEE Ç. Kalaca, A. Arzık, S. Kalaca, and P. Ünalan, “INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION”, Marmara Med J, vol. 14, no. 4, pp. 255–258, 2016.
ISNAD Kalaca, Çağrı et al. “INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION”. Marmara Medical Journal 14/4 (June 2016), 255-258.
JAMA Kalaca Ç, Arzık A, Kalaca S, Ünalan P. INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION. Marmara Med J. 2016;14:255–258.
MLA Kalaca, Çağrı et al. “INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION”. Marmara Medical Journal, vol. 14, no. 4, 2016, pp. 255-8.
Vancouver Kalaca Ç, Arzık A, Kalaca S, Ünalan P. INTRODUCTION TO CLINICAL PRACTICE: AN IMPORTANT CONTRIBUTION OF GENERAL MEDICINE TO MEDICAL EDUCATION. Marmara Med J. 2016;14(4):255-8.