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BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?

Year 2003, Volume: 16 Issue: 2, 121 - 123, 03.12.2016

Abstract

We report an 18 year old male patient with a known diagnosis of BRIC who presented with acute renal failure secondary to hyperbilirubinemia In three successive episodes. Renal replacement therapy was required in all three episodes but his renal function recovered to baseline creatinine on discharge. Proposed pathophysiology of ARF in the setting of hyperbilirubinemia includes direct tubulotoxlcity and sequestration of pigment casts within the tubular lumen causing tubular obstruction aggravated by dehydration. We emphasize the importance of vigorous hydration to be started with the impending attack to prevent progression to ARF.
Key Words : Acute Renal Failure, BRIC

References

  • Van Berge Henegouwen OP. Benign recurrent intrahepatic cholestasis and Byler's disease: one gene, two diseases?J Hepatol 1996; 25:395-397.
  • Schapiro RH, isseibacher lJ. Benign recurrent intrahepatic cholestasis. H Eng J Med 1963; 268:708-71 I.
  • Green J, Better OS. Systemic hypotension and renal failure in obstructive jaundice: Mechanistic and therapeutic aspects. J Am Soc Mephrol 1994;4:1 735-1 753.
  • CorateiH P, Passavanti Q. Pathophysiology of renal failure in obstructive jaundice. Miner Electrolyte Metab 1990; 16:61 -65.
  • Griffin MD, Grande JP, Wiesner RH, et al. Prolonged anuria complicating primary sclerosing cholangitis: successful outcome following orthotopic liver transplantation. Am J Kidney Dis 1998;31:360-363.
  • Yuceyar Y, Gumustas K, Erturk S, et al. The role of oxygen free radicals in acute renal failure complicating obstructive jaundice; an experimental study. HPB Surg 1998; 10:387- 393.
Year 2003, Volume: 16 Issue: 2, 121 - 123, 03.12.2016

Abstract

References

  • Van Berge Henegouwen OP. Benign recurrent intrahepatic cholestasis and Byler's disease: one gene, two diseases?J Hepatol 1996; 25:395-397.
  • Schapiro RH, isseibacher lJ. Benign recurrent intrahepatic cholestasis. H Eng J Med 1963; 268:708-71 I.
  • Green J, Better OS. Systemic hypotension and renal failure in obstructive jaundice: Mechanistic and therapeutic aspects. J Am Soc Mephrol 1994;4:1 735-1 753.
  • CorateiH P, Passavanti Q. Pathophysiology of renal failure in obstructive jaundice. Miner Electrolyte Metab 1990; 16:61 -65.
  • Griffin MD, Grande JP, Wiesner RH, et al. Prolonged anuria complicating primary sclerosing cholangitis: successful outcome following orthotopic liver transplantation. Am J Kidney Dis 1998;31:360-363.
  • Yuceyar Y, Gumustas K, Erturk S, et al. The role of oxygen free radicals in acute renal failure complicating obstructive jaundice; an experimental study. HPB Surg 1998; 10:387- 393.
There are 6 citations in total.

Details

Journal Section Case Reports
Authors

Serhan Tuğlular

Yeşim Özen-al Ahbad This is me

Gülçin Kantarcı This is me

Mehmet Koç This is me

Erol Avşar This is me

Çetin Özener This is me

Emel Akoğlu This is me

Publication Date December 3, 2016
Published in Issue Year 2003 Volume: 16 Issue: 2

Cite

APA Tuğlular, S., Özen-al Ahbad, Y., Kantarcı, G., Koç, M., et al. (2016). BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?. Marmara Medical Journal, 16(2), 121-123.
AMA Tuğlular S, Özen-al Ahbad Y, Kantarcı G, Koç M, Avşar E, Özener Ç, Akoğlu E. BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?. Marmara Med J. March 2016;16(2):121-123.
Chicago Tuğlular, Serhan, Yeşim Özen-al Ahbad, Gülçin Kantarcı, Mehmet Koç, Erol Avşar, Çetin Özener, and Emel Akoğlu. “BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?”. Marmara Medical Journal 16, no. 2 (March 2016): 121-23.
EndNote Tuğlular S, Özen-al Ahbad Y, Kantarcı G, Koç M, Avşar E, Özener Ç, Akoğlu E (March 1, 2016) BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?. Marmara Medical Journal 16 2 121–123.
IEEE S. Tuğlular, Y. Özen-al Ahbad, G. Kantarcı, M. Koç, E. Avşar, Ç. Özener, and E. Akoğlu, “BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?”, Marmara Med J, vol. 16, no. 2, pp. 121–123, 2016.
ISNAD Tuğlular, Serhan et al. “BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?”. Marmara Medical Journal 16/2 (March 2016), 121-123.
JAMA Tuğlular S, Özen-al Ahbad Y, Kantarcı G, Koç M, Avşar E, Özener Ç, Akoğlu E. BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?. Marmara Med J. 2016;16:121–123.
MLA Tuğlular, Serhan et al. “BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?”. Marmara Medical Journal, vol. 16, no. 2, 2016, pp. 121-3.
Vancouver Tuğlular S, Özen-al Ahbad Y, Kantarcı G, Koç M, Avşar E, Özener Ç, Akoğlu E. BENIGN RECURRENT INTRAHEPATIC CHOLESTASIS (BRIC): IS IT REALLY AS BENIGN AS ANTICIPATED?. Marmara Med J. 2016;16(2):121-3.