6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ

Cevdet Kaya; Orhan Koca; Muzaffer Keleş; Gülhan Yılmaz; Metin Öztürk; Hüseyin Kanberoğlu; M. Karaman

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Yıl 2009, Cilt: 22 Sayı: 1, 1 - 7, 04.05.2015

Cevdet Kaya Orhan Koca Muzaffer Keleş Gülhan Yılmaz Metin Öztürk Hüseyin Kanberoğlu M. Karaman

Öz

Anahtar Kelimeler

Kaynakça

1. Zlotta AR, Schulman CC. Biological markers in superficial bladder tumors and their prognostic significance. Urol Clin North Am 2000; 27:179-89.
2. Parkin DM, Pisanni P, Ferlay J. Global cancer statistics. CA-Can Clin 1999; 49: 33-64.
3. Bedük Y.Mesane tümörleri, Ürogenital tümörler, Temel Üroloji. Güneş Kitabevi: Ankara, 1998: 707–711.
4. Manunta A, Vincendeau S, Kiriakou G, Lobel B, Guille F. Non-transitional cell bladder carcinomas. BJU Int 2005; 95:497-502.
5. Chaudhary R, Bromley M, Clarke NW, et al. Prognostic relevance of micro-vessel density in cancer of the urinary bladder. Anticancer Res 1999; 19(4C):3479-84.
6. Petersen RO. Diagnosis and staging of bladder cancer. In: Petersen RO, ed. Urologic Pathology. 2'th edition. Philadelphia: Lippincott, 1992: 316.
7. Murphy WM. Disease of urinary bladder, urethra, ureters and renal pelvis. In: Murphy WM ed. Urological Pathology. Philadephia: Saunders, 1989: 134-146.
8. Rosai J. Urinary Tract: Kidney, renal pelvis, and ureter - bladder and male urethra.In: Rosai J, ed. Rosai and Ackerman's Surgical Pathology, in Volume 1. 9th ed. Philadelphia: Mosby, 2004: 1317-1359.
9. Lapham RL, Grignon D, Ro JY. Pathologic prognostic parameters in bladder urothelial biopsy, transurethral resection, and cystectomy specimens. Semin Diagn Pathol 1997; 14:109-22.
10. Heney NM, Natural history of bladder cancer. Urol Clin North Am 1992; 19: 429-432.
11. Weiner HG, Vooijis GP, Van’t Hof-Grootenboer B. Accuracy of urine cytology in the diagnosis of primary and recurrent bladder cancer. Acta Cytol 1993; 37: 163-169. 12. Richard E, Hautmann R. Urinary diversion: Ileal conduit to neobladder. J Urol 2003; 169:834-842.
13. Bricker EM. Bladder substitution after pelvic evisceration. Surg Clin North Am 1950; 30: 1511- 21.
14. Richie JP, Skinner DG. Ureterointestinal diversion. In: Walsh P, Gittes R, Perlmutter A, Stamey T, eds. Campbell’s Urology, 5th ed. Philadelphia: Saunders, 1986: 2601–2619.
15. Dahm P PD. The role of cystectomy in the management of superficial bladder cancer. Urol Integr Invest 2001; 6:134-138.
16. Lerner SP, Skinner DG. Radical cystectomy for bladder cancer. In: Volgezang NJ, Scardino PT, Shiply WU, Coffey DS, eds. Comprehensive Textbook of Genitourinary Oncology. 2nd edition. Philadelphia: Lippincott, Williams&Wilkins, 2000; 425-447.
17. Stein JJ, Lieskovsky G, Cote R, et al. Radical cystectomy in the treatment of invasive bladder cancer: Longterm results in 1054 patients. J Clin Oncol 2001;19: 666-675.
18. Millikan R, Dinney C, Swanson D, et al. Integrated therapy for locally advanced bladder cancer: final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative MVAC. J Clin Oncol 2001;19:4005–4013.
19. Sonpavde G, Petrylak DP. Perioperative chemotherapy for bladder cancer. Crit Rev Oncol Hematol 2006;57:133-144.
20. Skinner DG, Lieskovsky G. Management of invasive high-grade bladder cancer. In: Skinner DG, Lieskovsky G, eds. Diagnosis and Management of Genitourinary Cancer. Vol 1, Philadelphia: Saunders Comp, 1988: 295-312.
21. Stoter G, Splinter TAW, Child JA, et al. Combination chemotherapy with cisplatin and methotrexate in advanced TCC of the bladder. J Urol 1987; 137: 663-667.
22. Pagano F, Bassi P, Galctti TP, Meneghini A,Milani C, Artibani W, Garbeglio A. Results of contemporary radical cystectomy for invasive bladder cancer: A clinicopathological study with an emphasis on the inadequacy of the tumor, nodes and metastases classification. J Urol 1991; 145:45- 50.
23. Abel PD. Prognostic indices in transitional cell carcinoma of the bladder. Br J Urol 1988; 62:103- 109

6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ

Yıl 2009, Cilt: 22 Sayı: 1, 1 - 7, 04.05.2015

Cevdet Kaya Orhan Koca Muzaffer Keleş Gülhan Yılmaz Metin Öztürk Hüseyin Kanberoğlu M. Karaman

Öz

Giriş: Mesane kanseri üriner sistemin en sık görülen ikinci kanseridir. Radikal sistektomi ve üriner diversiyon, invaziv mesane tümörlerinin tedavisinde altın standarttır. Kliniğimizde radikal sistektomi operasyonu uygulanan hastalar retrospektif olarak değerlendirildi.

Yöntem: Ocak 2003 ve 2008 tarihleri arasında kliniğimizde mesane tümörü nedeni ile radikal sistektomi operasyonu uygulanmış 71 hasta retrospektif olarak demografik özellikler, preoperatif ve postoperatif patolojileri ile uygulanan üriner diversiyon yöntemleri açısından değerlendirildi. Ayrıca, operasyon sırasında ve hastaların takibinde görülen komplikasyonlar da incelendi.

Bulgular: Operasyon sonrası ortalama takip süresi 28,8 ay idi. Patolojik evreleme 13 hastada (%18) noninvaziv rapor edilirken, 20 hastada (%28) T2, 25 hastada (%35) T3, 14 hastada (%19.7) ise evre T4 tümör rapor edildi. Hastalardan 7’sinde squamoz hücreli karsinom bildirilirken, 24 hastada lenf nodu metastazı tespit edildi. Postoperatif erken dönemde 12 hastada yara yeri enfeksiyonu, 6 hastada yara evantrasyonu, 3 hastada ileus, 2 hastada üreteroileal anastomozdan idrar kaçağı vardı. Postoperatif geç dönemde ise birer olguda loop stenozu ve ürostomi materyaline karşı alerjik reaksiyon gözlemlendi. İki hastada exitus gelişmişti.

Anahtar Kelimeler

Mesane kanseri, Radikal sistektomi, İleal loop, Komplikasyonlar

Kaynakça

1. Zlotta AR, Schulman CC. Biological markers in superficial bladder tumors and their prognostic significance. Urol Clin North Am 2000; 27:179-89.
2. Parkin DM, Pisanni P, Ferlay J. Global cancer statistics. CA-Can Clin 1999; 49: 33-64.
3. Bedük Y.Mesane tümörleri, Ürogenital tümörler, Temel Üroloji. Güneş Kitabevi: Ankara, 1998: 707–711.
4. Manunta A, Vincendeau S, Kiriakou G, Lobel B, Guille F. Non-transitional cell bladder carcinomas. BJU Int 2005; 95:497-502.
5. Chaudhary R, Bromley M, Clarke NW, et al. Prognostic relevance of micro-vessel density in cancer of the urinary bladder. Anticancer Res 1999; 19(4C):3479-84.
6. Petersen RO. Diagnosis and staging of bladder cancer. In: Petersen RO, ed. Urologic Pathology. 2'th edition. Philadelphia: Lippincott, 1992: 316.
7. Murphy WM. Disease of urinary bladder, urethra, ureters and renal pelvis. In: Murphy WM ed. Urological Pathology. Philadephia: Saunders, 1989: 134-146.
8. Rosai J. Urinary Tract: Kidney, renal pelvis, and ureter - bladder and male urethra.In: Rosai J, ed. Rosai and Ackerman's Surgical Pathology, in Volume 1. 9th ed. Philadelphia: Mosby, 2004: 1317-1359.
9. Lapham RL, Grignon D, Ro JY. Pathologic prognostic parameters in bladder urothelial biopsy, transurethral resection, and cystectomy specimens. Semin Diagn Pathol 1997; 14:109-22.
10. Heney NM, Natural history of bladder cancer. Urol Clin North Am 1992; 19: 429-432.
11. Weiner HG, Vooijis GP, Van’t Hof-Grootenboer B. Accuracy of urine cytology in the diagnosis of primary and recurrent bladder cancer. Acta Cytol 1993; 37: 163-169. 12. Richard E, Hautmann R. Urinary diversion: Ileal conduit to neobladder. J Urol 2003; 169:834-842.
13. Bricker EM. Bladder substitution after pelvic evisceration. Surg Clin North Am 1950; 30: 1511- 21.
14. Richie JP, Skinner DG. Ureterointestinal diversion. In: Walsh P, Gittes R, Perlmutter A, Stamey T, eds. Campbell’s Urology, 5th ed. Philadelphia: Saunders, 1986: 2601–2619.
15. Dahm P PD. The role of cystectomy in the management of superficial bladder cancer. Urol Integr Invest 2001; 6:134-138.
16. Lerner SP, Skinner DG. Radical cystectomy for bladder cancer. In: Volgezang NJ, Scardino PT, Shiply WU, Coffey DS, eds. Comprehensive Textbook of Genitourinary Oncology. 2nd edition. Philadelphia: Lippincott, Williams&Wilkins, 2000; 425-447.
17. Stein JJ, Lieskovsky G, Cote R, et al. Radical cystectomy in the treatment of invasive bladder cancer: Longterm results in 1054 patients. J Clin Oncol 2001;19: 666-675.
18. Millikan R, Dinney C, Swanson D, et al. Integrated therapy for locally advanced bladder cancer: final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative MVAC. J Clin Oncol 2001;19:4005–4013.
19. Sonpavde G, Petrylak DP. Perioperative chemotherapy for bladder cancer. Crit Rev Oncol Hematol 2006;57:133-144.
20. Skinner DG, Lieskovsky G. Management of invasive high-grade bladder cancer. In: Skinner DG, Lieskovsky G, eds. Diagnosis and Management of Genitourinary Cancer. Vol 1, Philadelphia: Saunders Comp, 1988: 295-312.
21. Stoter G, Splinter TAW, Child JA, et al. Combination chemotherapy with cisplatin and methotrexate in advanced TCC of the bladder. J Urol 1987; 137: 663-667.
22. Pagano F, Bassi P, Galctti TP, Meneghini A,Milani C, Artibani W, Garbeglio A. Results of contemporary radical cystectomy for invasive bladder cancer: A clinicopathological study with an emphasis on the inadequacy of the tumor, nodes and metastases classification. J Urol 1991; 145:45- 50.
23. Abel PD. Prognostic indices in transitional cell carcinoma of the bladder. Br J Urol 1988; 62:103- 109

Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	Türkçe
Bölüm	Makaleler
Yazarlar	Cevdet Kaya Orhan Koca Bu kişi benim Muzaffer Keleş Bu kişi benim Gülhan Yılmaz Bu kişi benim Metin Öztürk Bu kişi benim Hüseyin Kanberoğlu Bu kişi benim M. Karaman Bu kişi benim
Yayımlanma Tarihi	4 Mayıs 2015
Yayımlandığı Sayı	Yıl 2009 Cilt: 22 Sayı: 1

Kaynak Göster

APA	Kaya, C., Koca, O., Keleş, M., Yılmaz, G., vd. (2015). 6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ. Marmara Medical Journal, 22(1), 1-7.
AMA	Kaya C, Koca O, Keleş M, Yılmaz G, Öztürk M, Kanberoğlu H, Karaman M. 6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ. Marmara Med J. Ağustos 2015;22(1):1-7.
Chicago	Kaya, Cevdet, Orhan Koca, Muzaffer Keleş, Gülhan Yılmaz, Metin Öztürk, Hüseyin Kanberoğlu, ve M. Karaman. “6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ”. Marmara Medical Journal 22, sy. 1 (Ağustos 2015): 1-7.
EndNote	Kaya C, Koca O, Keleş M, Yılmaz G, Öztürk M, Kanberoğlu H, Karaman M (01 Ağustos 2015) 6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ. Marmara Medical Journal 22 1 1–7.
IEEE	C. Kaya, “6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ”, Marmara Med J, c. 22, sy. 1, ss. 1–7, 2015.
ISNAD	Kaya, Cevdet vd. “6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ”. Marmara Medical Journal 22/1 (Ağustos 2015), 1-7.
JAMA	Kaya C, Koca O, Keleş M, Yılmaz G, Öztürk M, Kanberoğlu H, Karaman M. 6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ. Marmara Med J. 2015;22:1–7.
MLA	Kaya, Cevdet vd. “6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ”. Marmara Medical Journal, c. 22, sy. 1, 2015, ss. 1-7.
Vancouver	Kaya C, Koca O, Keleş M, Yılmaz G, Öztürk M, Kanberoğlu H, Karaman M. 6 YILLIK RADİKAL SİSTEKTOMİ DENEYİMİMİZ. Marmara Med J. 2015;22(1):1-7.

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