Prevalence of fatty liver disease in patients with inflammatory bowel disease: a transient elastography study on the basis of a controlled attenuation parameter

Yıl 2019, Cilt: 32 Sayı: 2, 68 - 70, 31.05.2019

Haluk Tarik Kanı İlknur Delıktas Yusuf Yılmaz

https://doi.org/10.5472/marumj.570907

Cited By: 4

Öz

Objective: Inflammatory bowel disease (IBD) is a chronic
recurrent inflammatory disorder of the gastrointestinal tract
which has an unknown etiology. In this study, we aimed to
investigate the fatty liver disease frequency in IBD patients
using transient elastography (TE) which is a non-invasive and
accurate method for the diagnosis of liver fibrosis.
Material and Methods: The data were collected from
registered patients retrospectively. On the basis of previous
studies, a cut-off value of 238 dB/m for controlled attenuation
parameter (CAP) was used for the diagnosis of hepatic steatosis.
In this study we have also settled CAP value above 238 dB/m
as fatty liver.
Results: A total of 99 patients were enrolled in the study.
Mean age was 45.59 ± 11.72 years and 41 (41.4%) patients were
female. Fifty-eight patients (58.6%) had Crohn’s disease, 39
(39.4%) had ulcerative colitis and 2 (2.0%) had indeterminate
colitis. In 8 (8.1%) patients extra-large probe and in 91 (91.9%)
patients medium probe was used to detect liver steatosis. Fatty
liver disease was detected in 44 (44.4%) patients with IBD.
Conclusion: Despite the nutrition disorders in IBD,
fatty liver disease was seen in 44.4% of patients in our
cohort. However, fatty liver disease may be seen without any
aminotransferase elevation in IBD patients. Therefore, liver
steatosis should always be kept in mind and careful attention
should be paid during follow-up of patients with IBD in our
daily practice.

Anahtar Kelimeler

Continued attenuation parameter, Inflammatory bowel disease, Non-alcoholic fatty liver disease

Kaynakça

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