Research Article
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Year 2024, Volume: 37 Issue: 2, 157 - 165, 31.05.2024
https://doi.org/10.5472/marumj.1483038

Abstract

References

  • Lenka A, Jankovic J. Tremor syndromes: An updated review. Front Neurol 2021; 12: 684835. doi: 10.3389/ fneur.2021.684835
  • Louis ED. Diagnosis and management of tremor. Continuum 2016; 22: 1143-58. doi: 10.1212/CON.000.000.0000000346
  • Louis ED. Essential tremor: a nuanced approach to the clinical features. Pract Neurol 2019; 19: 389-98. doi: 10.1136/ practneurol-2018-002183
  • Chen JJ, Swope DM. Essential tremor: diagnosis and treatment. Pharmacotherapy 2003; 23: 1105-22. doi: 10.1592/ phco.23.10.1105.32750
  • Bhatia KP, Bain P, Bajaj N, et al. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Mov Disord 2018; 33: 75-87. doi: 10.1002/mds.27121
  • Saifee TA. Tremor. Br Med Bull 2019; 130: 51-63. doi: 10.1093/ bmb/ldz017
  • Louis ED, Broussolle E, Goetz CG, Krack P, Kaufmann P, Mazzoni P. Historical underpinnings of the term essential tremor in the late 19th century. Neurology 2008; 71: 856-9. doi: 10.1212/01.wnl.000.032.5564.38165.d1
  • Zesiewicz TA, Kuo SH. Essential tremor. BMJ Clin Evid 2015; 12: 1206-1247.
  • Louis ED, Ottman R. How many people in the USA have essential tremor? Deriving a population estimate based on epidemiological data. Tremor Other Hyperkinet Mov (N Y) 2014; 4: 259-9. doi: 10.7916/D8TT4P4B
  • Lorenz D, Schwieger D, Moises H, Deuschl G. Quality of life and personality in essential tremor patients. Mov Disord 2006; 21: 1114-8. doi: 10.1002/mds.20884
  • Louis ED. Etiology of essential tremor: Should we be searching for environmental causes? Mov Disord 2001; 16: 822-9. doi: 10.1002/mds.1183
  • George MS, Lydiard RB. Social phobia secondary to physical disability. A review of benign essential tremor (BET) and stuttering. Psychosomatics 1994; 35: 520-3. doi: 10.1016/ s0033-3182(94)71720-5
  • Traub RE, Gerbin M, Mullaney MM, Louis ED. Development of an essential tremor embarrassment assessment. Parkinsonism Relat Disord 2010; 16: 661-665. doi: 10.1016/j. parkreldis.2010.08.017
  • Lonneke ML, Breteler MM. Epidemiology of Parkinson’s disease. Lancet Neurol 2006; 5: 525-35. doi: 10.1016/S1474- 4422(06)70471-9
  • Gulcher JR, Jónsson P, Kong A, et al. Mapping of a familial essential tremor gene to chromosome 3q13. Nat Genet 1998; 6: 150-1. doi: 10.1038/ng0997-84
  • Higgins JJ, Pho LT, Nee LE. A gene (ETM) for essential tremor maps to chromosome 2p22-p25. Mov Disord 1997; 12: 859-64. doi: 10.1002/mds.870120605
  • Shatunov A, Sambuughin N, Jankovic J, et al. Genomewide scans in North American families reveal genetic linkage of essential tremor to a region on chromosome 6p23. Brain 2006; 129: 2318-31. doi: 10.1093/brain/awl120
  • Rajput AH, Rajput A. Medical treatment of essential tremor. J Cent Nerv Syst Dis 2014; 6: 29-39. doi: 10.4137/JCNSD. S13570
  • Stefansson H, Steinberg S, Petursson H, et al. Variant in the sequence of the LINGO1 gene confers risk of essential tremor. Nat Genet 2009; 41: 277-9. doi: 10.1038/ng.299
  • Deuschl G, Raethjen J, Hellriegel H, Rodger E. Treatment of patients with essential tremor. Lancet Neurol 2011; 10: 148-61. doi: 10.1016/S1474-4422(10)70322-7
  • Sharma S, Pandey S. Treatment of essential tremor: current status. Postgrad Med J 2020; 96: 84-93. doi: 10.1136/ postgradmedj-2019-136647
  • Mohammed N, Patra D, Nanda A. A meta-analysis of outcomes and complications of magnetic resonance-guided focused ultrasound in the treatment of essential tremor. Neurosurg Focus 2018; 44: E4. doi: 10.3171/2017.11.FOCUS17628
  • Fromme NP, Camenzind M, Riener R, Rossi MR. Need for mechanically and ergonomically enhanced tremorsuppression orthoses for the upper limb: a systematic review. J Neuroeng Rehabil 2019; 16: 93. doi: https://doi.org/10.1186/ s12984.019.0543-7
  • Louis ED, Ferreira JJ. How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor. Mov Disord 2010; 25: 534-41. doi: 10.1002/ mds.22838
  • Verhoeff MC, Koutris M, Vries R, Berendse HW, Dijk KD, Lobbezoo F. Salivation in Parkinson’s disease: A scoping review. Gerodontology 2023; 40: 26-38. doi: 10.1111/ger.12628
  • Chen LK. Urbanization and population aging: Converging trends of demographic transitions in modern world. Arch Gerontol Geriatr 2022; 101: 104709. doi: 10.1016/j. archger.2022.104709
  • Louis ED, Ottman R, Hauser W A. How common is the most common adult movement disorder? Estimates of the prevalence of essential tremor throughout the world. Mov Disord 1998; 13: 5-10. doi: 10.1002/mds.870130105
  • Rajput AH, Offord KP, Beard CM, Kurland LT. Essential tremor in Rochester, Minnesota: a 45-year study. J Neurol Neurosurg Psychiatry 1984; 47: 466-70. doi: 10.1136/jnnp.47.5.466
  • Cleeves L, Findley LJ, Koller W. Lack of association between essential tremor and Parkinson’s disease. Ann Neurol 1988; 24: 23-26. doi: 10.1002/ana.410240106
  • Koller WC, Busenbark K, Miner K. The relationship of essential tremor to other movement disorders: report on 678 patients. Ann Neurol 1994; 35: 717-23. doi: https://doi. org/10.1002/ana.410350613
  • Geraghty JJ, Jankovic J, Zetusky WJ. Association between Essential Tremor and Parkinsons-Disease. Ann Neurol 1985; 17: 329-33. doi: 10.1002/ana.410170404
  • Shahed J, Jankovic J. Exploring the relationship between essential tremor and Parkinson’s disease. Parkinsonism Relat Disord 2007; 13: 67-76. doi: 10.1016/j. parkreldis.2006.05.033
  • Guler S, Caylan A, Turan FN, Dağdeviren N. The prevalence of essential tremor in Edirne and its counties accompanied comorbid conditions. Neurological Research 2019; 41: 847- 56. doi: https://doi.org/10.1080/01616.412.2019.1628409
  • Sur H, İlhan S, Erdoğan H, Öztürk E, Taşdemir M, Börü TU. Prevalence of essential tremor: a door-to-door survey in Sile, Istanbul, Turkey. Parkinsonism Relat Disord 2009; 15: 101-4. doi: 10.1016/j.parkreldis.2008.03.009
  • Louis ED, Wendt KJ, Pullman SL. Is essential tremor symmetric? Observational data from a community-based study of essential tremor. Arch Neurol 1998; 55: 1553-9. doi: 10.1001/archneur.55.12.1553
  • Hewer RL, Cooper R, Morgan MH. An investigation into the value of treating intention tremor by weighting the affected limb. Brain 1972; 95: 579-90. doi: 10.1093/brain/95.3.579
  • Heroux ME, Pari G, Norman KE. The effect of inertial loading on wrist postural tremor in essential tremor. Clin Neurophysiol 2009; 120: 1020-9. doi: 10.1016/j.clinph.2009.03.012
  • Bhidayasiri R, Maytharakcheep S, Phumphid S, Maetzler W. Improving functional disability in patients with tremor: A clinical perspective of the efficacies, considerations, and challenges of assistive technology. J Neurol Sci 2022; 435: 120197. doi: 10.1016/j.jns.2022.120197
  • Herrnstadt G, Menon C. Voluntary-driven elbow orthosis with speed-controlled tremor suppression. Front Bioeng and Biotechnol 2016; 4: 29. doi: https://doi.org/10.3389/ fbioe.2016.00029
  • Taheri B, Case D, Richer E. Adaptive suppression of severe pathological tremor by Torque Estimation Method. Ieee-Asme Transactions on Mechatronics 2015; 20: 717-27. doi: 10.1109/ TMECH.2014.231.7948
  • Rudraraju S, Nguyen T. Wearable tremor reduction device (TRD) for human hands and arms. Design of Medical Devices Conference 2018; doi: 10.1115/DMD2018-6918
  • Fromme NP, Camenzind M, Riener R, Rossi MR. Design of a lightweight passive orthosis for tremor suppression. Journal of NeuroEngineering and Rehabilitation 2020; 17: 47. doi: https://doi.org/10.1186/s12984.020.00673-7
  • Skaramagkas V, Andrikopoulos G, Manesis S. An Experimental Investigation of Essential Hand Tremor Suppression via a Soft Exoskeletal Glove. European Control Conference 2020; 1: 889-94. doi: 10.23919/ECC51009.2020.914.3932
  • Pathak A, Redmond AJ, Allen M, Chou KL. A noninvasive handheld assistive device to accommodate essential tremor: a pilot study. Mov Disord 2014; 29: 838-42. doi: 10.1002/ mds.25796
  • Ryden LE, Matar E, Szeto JYY, Hammond DA, Clouston P, Lewis SJG. Shaken not Stirred: A pilot study testing a gyroscopic spoon stabilization device in Parkinson’s disease and tremor. Ann Indian Acad Neurol 2020; 23: 409-11. doi: 10.4103/aian.AIAN_251_19

Developing a wearable device for upper extremity tremors

Year 2024, Volume: 37 Issue: 2, 157 - 165, 31.05.2024
https://doi.org/10.5472/marumj.1483038

Abstract

Objective: This project aims to develop a wearable device to suppress both the essential and resting tremor and investigate its
effectiveness.
Materials and Methods: This study details the development and assessment of a wearable device for upper extremity tremors. The
wearable device underwent a comprehensive design and a prototype was produced with a 3D-printer. To refine the functionality of
the prototype, a motor that mimics tremor was attached to a 3D-printed prototype. Then, the printed prototype was applied to the
hand model, and tested its effectiveness for tremor suppressing. The wearable device was further investigated on patients with essential
tremor and Parkinson`s disease seeking treatment at Neurology Clinics. We recorded the tremor data and processed and visualized the
recorded data by using the MatLab (version R2021a, MathWorks Inc., USA) software.
Results: The wearable device effectively decreased the tremors both during the simulation phase and the patient testing phase. The
data from the wearable device revealed a notable decrease in the amplitude of the tremor. This decrease signifies an achievement of
tremor suppression.
Conclusion: The prototype of the wearable device signifies a remarkable efficacy in tremor supression. It holds promise for being a
potential solution to alleviate the tremor symptoms of essential tremor and Parkinson`s disease patients.

References

  • Lenka A, Jankovic J. Tremor syndromes: An updated review. Front Neurol 2021; 12: 684835. doi: 10.3389/ fneur.2021.684835
  • Louis ED. Diagnosis and management of tremor. Continuum 2016; 22: 1143-58. doi: 10.1212/CON.000.000.0000000346
  • Louis ED. Essential tremor: a nuanced approach to the clinical features. Pract Neurol 2019; 19: 389-98. doi: 10.1136/ practneurol-2018-002183
  • Chen JJ, Swope DM. Essential tremor: diagnosis and treatment. Pharmacotherapy 2003; 23: 1105-22. doi: 10.1592/ phco.23.10.1105.32750
  • Bhatia KP, Bain P, Bajaj N, et al. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Mov Disord 2018; 33: 75-87. doi: 10.1002/mds.27121
  • Saifee TA. Tremor. Br Med Bull 2019; 130: 51-63. doi: 10.1093/ bmb/ldz017
  • Louis ED, Broussolle E, Goetz CG, Krack P, Kaufmann P, Mazzoni P. Historical underpinnings of the term essential tremor in the late 19th century. Neurology 2008; 71: 856-9. doi: 10.1212/01.wnl.000.032.5564.38165.d1
  • Zesiewicz TA, Kuo SH. Essential tremor. BMJ Clin Evid 2015; 12: 1206-1247.
  • Louis ED, Ottman R. How many people in the USA have essential tremor? Deriving a population estimate based on epidemiological data. Tremor Other Hyperkinet Mov (N Y) 2014; 4: 259-9. doi: 10.7916/D8TT4P4B
  • Lorenz D, Schwieger D, Moises H, Deuschl G. Quality of life and personality in essential tremor patients. Mov Disord 2006; 21: 1114-8. doi: 10.1002/mds.20884
  • Louis ED. Etiology of essential tremor: Should we be searching for environmental causes? Mov Disord 2001; 16: 822-9. doi: 10.1002/mds.1183
  • George MS, Lydiard RB. Social phobia secondary to physical disability. A review of benign essential tremor (BET) and stuttering. Psychosomatics 1994; 35: 520-3. doi: 10.1016/ s0033-3182(94)71720-5
  • Traub RE, Gerbin M, Mullaney MM, Louis ED. Development of an essential tremor embarrassment assessment. Parkinsonism Relat Disord 2010; 16: 661-665. doi: 10.1016/j. parkreldis.2010.08.017
  • Lonneke ML, Breteler MM. Epidemiology of Parkinson’s disease. Lancet Neurol 2006; 5: 525-35. doi: 10.1016/S1474- 4422(06)70471-9
  • Gulcher JR, Jónsson P, Kong A, et al. Mapping of a familial essential tremor gene to chromosome 3q13. Nat Genet 1998; 6: 150-1. doi: 10.1038/ng0997-84
  • Higgins JJ, Pho LT, Nee LE. A gene (ETM) for essential tremor maps to chromosome 2p22-p25. Mov Disord 1997; 12: 859-64. doi: 10.1002/mds.870120605
  • Shatunov A, Sambuughin N, Jankovic J, et al. Genomewide scans in North American families reveal genetic linkage of essential tremor to a region on chromosome 6p23. Brain 2006; 129: 2318-31. doi: 10.1093/brain/awl120
  • Rajput AH, Rajput A. Medical treatment of essential tremor. J Cent Nerv Syst Dis 2014; 6: 29-39. doi: 10.4137/JCNSD. S13570
  • Stefansson H, Steinberg S, Petursson H, et al. Variant in the sequence of the LINGO1 gene confers risk of essential tremor. Nat Genet 2009; 41: 277-9. doi: 10.1038/ng.299
  • Deuschl G, Raethjen J, Hellriegel H, Rodger E. Treatment of patients with essential tremor. Lancet Neurol 2011; 10: 148-61. doi: 10.1016/S1474-4422(10)70322-7
  • Sharma S, Pandey S. Treatment of essential tremor: current status. Postgrad Med J 2020; 96: 84-93. doi: 10.1136/ postgradmedj-2019-136647
  • Mohammed N, Patra D, Nanda A. A meta-analysis of outcomes and complications of magnetic resonance-guided focused ultrasound in the treatment of essential tremor. Neurosurg Focus 2018; 44: E4. doi: 10.3171/2017.11.FOCUS17628
  • Fromme NP, Camenzind M, Riener R, Rossi MR. Need for mechanically and ergonomically enhanced tremorsuppression orthoses for the upper limb: a systematic review. J Neuroeng Rehabil 2019; 16: 93. doi: https://doi.org/10.1186/ s12984.019.0543-7
  • Louis ED, Ferreira JJ. How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor. Mov Disord 2010; 25: 534-41. doi: 10.1002/ mds.22838
  • Verhoeff MC, Koutris M, Vries R, Berendse HW, Dijk KD, Lobbezoo F. Salivation in Parkinson’s disease: A scoping review. Gerodontology 2023; 40: 26-38. doi: 10.1111/ger.12628
  • Chen LK. Urbanization and population aging: Converging trends of demographic transitions in modern world. Arch Gerontol Geriatr 2022; 101: 104709. doi: 10.1016/j. archger.2022.104709
  • Louis ED, Ottman R, Hauser W A. How common is the most common adult movement disorder? Estimates of the prevalence of essential tremor throughout the world. Mov Disord 1998; 13: 5-10. doi: 10.1002/mds.870130105
  • Rajput AH, Offord KP, Beard CM, Kurland LT. Essential tremor in Rochester, Minnesota: a 45-year study. J Neurol Neurosurg Psychiatry 1984; 47: 466-70. doi: 10.1136/jnnp.47.5.466
  • Cleeves L, Findley LJ, Koller W. Lack of association between essential tremor and Parkinson’s disease. Ann Neurol 1988; 24: 23-26. doi: 10.1002/ana.410240106
  • Koller WC, Busenbark K, Miner K. The relationship of essential tremor to other movement disorders: report on 678 patients. Ann Neurol 1994; 35: 717-23. doi: https://doi. org/10.1002/ana.410350613
  • Geraghty JJ, Jankovic J, Zetusky WJ. Association between Essential Tremor and Parkinsons-Disease. Ann Neurol 1985; 17: 329-33. doi: 10.1002/ana.410170404
  • Shahed J, Jankovic J. Exploring the relationship between essential tremor and Parkinson’s disease. Parkinsonism Relat Disord 2007; 13: 67-76. doi: 10.1016/j. parkreldis.2006.05.033
  • Guler S, Caylan A, Turan FN, Dağdeviren N. The prevalence of essential tremor in Edirne and its counties accompanied comorbid conditions. Neurological Research 2019; 41: 847- 56. doi: https://doi.org/10.1080/01616.412.2019.1628409
  • Sur H, İlhan S, Erdoğan H, Öztürk E, Taşdemir M, Börü TU. Prevalence of essential tremor: a door-to-door survey in Sile, Istanbul, Turkey. Parkinsonism Relat Disord 2009; 15: 101-4. doi: 10.1016/j.parkreldis.2008.03.009
  • Louis ED, Wendt KJ, Pullman SL. Is essential tremor symmetric? Observational data from a community-based study of essential tremor. Arch Neurol 1998; 55: 1553-9. doi: 10.1001/archneur.55.12.1553
  • Hewer RL, Cooper R, Morgan MH. An investigation into the value of treating intention tremor by weighting the affected limb. Brain 1972; 95: 579-90. doi: 10.1093/brain/95.3.579
  • Heroux ME, Pari G, Norman KE. The effect of inertial loading on wrist postural tremor in essential tremor. Clin Neurophysiol 2009; 120: 1020-9. doi: 10.1016/j.clinph.2009.03.012
  • Bhidayasiri R, Maytharakcheep S, Phumphid S, Maetzler W. Improving functional disability in patients with tremor: A clinical perspective of the efficacies, considerations, and challenges of assistive technology. J Neurol Sci 2022; 435: 120197. doi: 10.1016/j.jns.2022.120197
  • Herrnstadt G, Menon C. Voluntary-driven elbow orthosis with speed-controlled tremor suppression. Front Bioeng and Biotechnol 2016; 4: 29. doi: https://doi.org/10.3389/ fbioe.2016.00029
  • Taheri B, Case D, Richer E. Adaptive suppression of severe pathological tremor by Torque Estimation Method. Ieee-Asme Transactions on Mechatronics 2015; 20: 717-27. doi: 10.1109/ TMECH.2014.231.7948
  • Rudraraju S, Nguyen T. Wearable tremor reduction device (TRD) for human hands and arms. Design of Medical Devices Conference 2018; doi: 10.1115/DMD2018-6918
  • Fromme NP, Camenzind M, Riener R, Rossi MR. Design of a lightweight passive orthosis for tremor suppression. Journal of NeuroEngineering and Rehabilitation 2020; 17: 47. doi: https://doi.org/10.1186/s12984.020.00673-7
  • Skaramagkas V, Andrikopoulos G, Manesis S. An Experimental Investigation of Essential Hand Tremor Suppression via a Soft Exoskeletal Glove. European Control Conference 2020; 1: 889-94. doi: 10.23919/ECC51009.2020.914.3932
  • Pathak A, Redmond AJ, Allen M, Chou KL. A noninvasive handheld assistive device to accommodate essential tremor: a pilot study. Mov Disord 2014; 29: 838-42. doi: 10.1002/ mds.25796
  • Ryden LE, Matar E, Szeto JYY, Hammond DA, Clouston P, Lewis SJG. Shaken not Stirred: A pilot study testing a gyroscopic spoon stabilization device in Parkinson’s disease and tremor. Ann Indian Acad Neurol 2020; 23: 409-11. doi: 10.4103/aian.AIAN_251_19
There are 45 citations in total.

Details

Primary Language English
Subjects Surgery (Other)
Journal Section Original Research
Authors

Sercan Doğukan Yıldız 0000-0002-2971-2402

Gazi Akgün 0000-0002-8154-5883

Dilek Gunal This is me 0000-0002-8533-2922

Erkan Kaplanoğlu 0000-0002-8152-1291

Caner Akuner 0000-0001-8397-3454

Ümit Şehirli 0000-0001-6261-4567

Publication Date May 31, 2024
Submission Date November 23, 2023
Acceptance Date December 26, 2023
Published in Issue Year 2024 Volume: 37 Issue: 2

Cite

APA Yıldız, S. D., Akgün, G., Gunal, D., Kaplanoğlu, E., et al. (2024). Developing a wearable device for upper extremity tremors. Marmara Medical Journal, 37(2), 157-165. https://doi.org/10.5472/marumj.1483038
AMA Yıldız SD, Akgün G, Gunal D, Kaplanoğlu E, Akuner C, Şehirli Ü. Developing a wearable device for upper extremity tremors. Marmara Med J. May 2024;37(2):157-165. doi:10.5472/marumj.1483038
Chicago Yıldız, Sercan Doğukan, Gazi Akgün, Dilek Gunal, Erkan Kaplanoğlu, Caner Akuner, and Ümit Şehirli. “Developing a Wearable Device for Upper Extremity Tremors”. Marmara Medical Journal 37, no. 2 (May 2024): 157-65. https://doi.org/10.5472/marumj.1483038.
EndNote Yıldız SD, Akgün G, Gunal D, Kaplanoğlu E, Akuner C, Şehirli Ü (May 1, 2024) Developing a wearable device for upper extremity tremors. Marmara Medical Journal 37 2 157–165.
IEEE S. D. Yıldız, G. Akgün, D. Gunal, E. Kaplanoğlu, C. Akuner, and Ü. Şehirli, “Developing a wearable device for upper extremity tremors”, Marmara Med J, vol. 37, no. 2, pp. 157–165, 2024, doi: 10.5472/marumj.1483038.
ISNAD Yıldız, Sercan Doğukan et al. “Developing a Wearable Device for Upper Extremity Tremors”. Marmara Medical Journal 37/2 (May 2024), 157-165. https://doi.org/10.5472/marumj.1483038.
JAMA Yıldız SD, Akgün G, Gunal D, Kaplanoğlu E, Akuner C, Şehirli Ü. Developing a wearable device for upper extremity tremors. Marmara Med J. 2024;37:157–165.
MLA Yıldız, Sercan Doğukan et al. “Developing a Wearable Device for Upper Extremity Tremors”. Marmara Medical Journal, vol. 37, no. 2, 2024, pp. 157-65, doi:10.5472/marumj.1483038.
Vancouver Yıldız SD, Akgün G, Gunal D, Kaplanoğlu E, Akuner C, Şehirli Ü. Developing a wearable device for upper extremity tremors. Marmara Med J. 2024;37(2):157-65.