Yara İyileşmesi ve Oksidatif Stres

Halil Aksoy; Özlem Bingöl Özakpınar

doi:10.12991/mpj.2014187243

Yara İyileşmesi ve Oksidatif Stres

Abstract

Aerobik hücrelerin normal metabolik yolaklarında bulunan

çeşitli enzimler ile travma, enfeksiyon, reperfüzyon ve

inflamasyon gibi çevresel faktörler reaktif oksijen türlerini

(ROT) oluşturur. Bu radikaller bir veya birden fazla

eşleşmemiş elektron içeren moleküller olup, yüksek kimyasal

aktivitelerinden dolayı hücresel makromoleküllerin hasarına

neden olurlar. Son yıllarda oksidatif stresin hem savunma

sisteminde hem de yara iyileşmesinde de rol aldığı birçok

çalışmada ortaya konmuştur. Diğer taraftan, yara

iyileşmesinde büyük bir role sahip olan ROT’un etki

mekanizmasıtam olarak aydılatıamamışı. Bu nedenle,

ROT’un oluşmu ve oluşn bu üülerin detoksifikasyonu

yara iyileşesinde büü öem kazanmaktadı. Bu da tedavi

içn yeni yötemlerin gelişesine öemli katkıar

sağayacaktı. Bu çlışada, yara iyileşesinde rolüolan

çştli antioksidan moleküler ile ROT’ un detoksifiye

enzimleri anlatıacaktı.

Anahtar Kelimeler: Antioksidan, oksidatif stres, reaktif

oksijen türleri, yara iyileşmesi

Keywords

Antioksidan, oksidatif stres, reaktif oksijen türleri, yara iyileşmesi

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Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Halil Aksoy

Özlem Bingöl Özakpınar This is me

Publication Date

September 12, 2014

Submission Date

September 12, 2014

Acceptance Date

-

Published in Issue

Year 2014 Volume: 18 Number: 3

DOI

https://doi.org/10.12991/mpj.2014187243

IZ

https://izlik.org/JA63JU67DT

Cite

RIS / Bibtex

APA

Aksoy, H., & Bingöl Özakpınar, Ö. (2014). Yara İyileşmesi ve Oksidatif Stres. Marmara Pharmaceutical Journal, 18(3), 153-158. https://doi.org/10.12991/mpj.2014187243

AMA

1.Aksoy H, Bingöl Özakpınar Ö. Yara İyileşmesi ve Oksidatif Stres. J Res Pharm. 2014;18(3):153-158. doi:10.12991/mpj.2014187243

Chicago

Aksoy, Halil, and Özlem Bingöl Özakpınar. 2014. “Yara İyileşmesi Ve Oksidatif Stres”. Marmara Pharmaceutical Journal 18 (3): 153-58. https://doi.org/10.12991/mpj.2014187243.

EndNote

Aksoy H, Bingöl Özakpınar Ö (November 1, 2014) Yara İyileşmesi ve Oksidatif Stres. Marmara Pharmaceutical Journal 18 3 153–158.

IEEE

[1]H. Aksoy and Ö. Bingöl Özakpınar, “Yara İyileşmesi ve Oksidatif Stres”, J Res Pharm, vol. 18, no. 3, pp. 153–158, Nov. 2014, doi: 10.12991/mpj.2014187243.

ISNAD

Aksoy, Halil - Bingöl Özakpınar, Özlem. “Yara İyileşmesi Ve Oksidatif Stres”. Marmara Pharmaceutical Journal 18/3 (November 1, 2014): 153-158. https://doi.org/10.12991/mpj.2014187243.

JAMA

1.Aksoy H, Bingöl Özakpınar Ö. Yara İyileşmesi ve Oksidatif Stres. J Res Pharm. 2014;18:153–158.

MLA

Aksoy, Halil, and Özlem Bingöl Özakpınar. “Yara İyileşmesi Ve Oksidatif Stres”. Marmara Pharmaceutical Journal, vol. 18, no. 3, Nov. 2014, pp. 153-8, doi:10.12991/mpj.2014187243.

Vancouver

1.Halil Aksoy, Özlem Bingöl Özakpınar. Yara İyileşmesi ve Oksidatif Stres. J Res Pharm. 2014 Nov. 1;18(3):153-8. doi:10.12991/mpj.2014187243