Assessment of the Relationship between Vitamin D Deficiency and the Development of Hyperemesis Gravidarum

Osman Eren Çetinkaya; İlke Özer Aslan; Alev Kural; Keziban Doğan

doi:10.19127/mbsjohs.1221005

EN

Assessment of the Relationship between Vitamin D Deficiency and the Development of Hyperemesis Gravidarum

Abstract

Object: Hyperemesis gravidarum, the leading cause of hospitalization in the first trimester, is observed in 0.3% to 3.6% of all pregnant women worldwide. Vitamin D is a significant vitamin for human health, and vitamin D deficiency in the pregnant women population in Turkey is a common pathology. In this context, this study was carried out to assess the relationship between vitamin D deficiency and the development of hyperemesis gravidarum. Methods: The population of this prospective, single-center, case-controlled study consisted of pregnant women diagnosed with hyperemesis gravidarum. In the end, 23 pregnant women with hyperemesis gravidarum were included in the patient group, and 30 healthy pregnant women with demographic characteristics that match those with hyperemesis gravidarum were included in the control group. The Vitamin D and hematocrit levels were compared between the two groups. Results: There was no significant difference between the patient and control groups in the serum vitamin D (p = 0.760) and hematocrit (p = 0.149) levels. Overall, only 9 (17%) of the 53 pregnant women had sufficient (> 20 ng / ml) vitamin D. There was no significant difference between the patient and control groups in the number of patients with vitamin D deficiency. Conclusion: The study findings did not indicate a correlation between vitamin D deficiency and hyperemesis gravidarum. Further large-scale studies are needed to establish the absence of a relationship between vitamin D deficiency and hyperemesis gravidarum. On the other hand, the fact that only 17% of the pregnant women who participated in this study had sufficient vitamin D revealed the need to emphasize using vitamin D supplements in pregnant women as early as possible in the first trimester.

Keywords

Hyperemesis gravidarum , nausea , pregnancy , vitamin D , vomiting

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Osman Eren Çetinkaya
0000-0001-6581-3465
Türkiye

İlke Özer Aslan ^*
0000-0002-3175-8354
Türkiye

Alev Kural
0000-0003-1459-4316
Türkiye

Keziban Doğan
0000-0003-2297-8635
Türkiye

Publication Date

August 31, 2023

Submission Date

December 20, 2022

Acceptance Date

May 3, 2023

Published in Issue

Year 2023 Volume: 9 Number: 3

DOI

https://doi.org/10.19127/mbsjohs.1221005

IZ

https://izlik.org/JA45RY58DZ

Vancouver

1.Osman Eren Çetinkaya, İlke Özer Aslan, Alev Kural, Keziban Doğan. Assessment of the Relationship between Vitamin D Deficiency and the Development of Hyperemesis Gravidarum. Mid Blac Sea J Health Sci. 2023 Aug. 1;9(3):520-7. doi:10.19127/mbsjohs.1221005

Assessment of the Relationship between Vitamin D Deficiency and the Development of Hyperemesis Gravidarum

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Assessment of the Relationship between Vitamin D Deficiency and the Development of Hyperemesis Gravidarum

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