Objective: Type 1
diabetes mellitus (T1DM) is one of the most common chronic endocrine diseases encountered
in childhood and adolescent periods. This study aims to assess the biochemical
and epidemiological characteristics of children monitored for T1DM diagnosis in
Ordu.
Methods: This study
investigated some biochemical and epidemiological characteristics of a total of
40 (20 boys, 20 girls) children ranging in age from 3 to 16 years with first
diagnosis and follow-up at Ordu University Faculty of Medicine Education and
Research Hospital Pediatric Health and Diseases Department from 2012 to 2016. Children
participating in the study were divided into 2 groups as aged 3-9 years and
10-16 years. Group I included children aged from 3-9 years, while Group II
included children aged from 10-16 years. The distribution according to gender
and peak age for first diagnosis were examined. The study retrospectively
investigated the fasting plasma glucose, HbA1C, AST, ALT, Na, K, Cl,
triglyceride, cholesterol, BUN, creatinine, white cells, hemoglobin, urine pH,
urine density, urine glucose, blood pH and HCO3 values of pediatric patients
applying for the first time and receiving diagnosis of T1DM.
Results: Our
patients included 20 girls (50%) and 20 boys (50%). The lowest diabetes age was
3 years with highest 16 years. According to age distribution of patients, the
peak age of disease was 11 years (22.5%) and there were 17 patients (42.5%) in
the 3-9 age group and 23 (57.5%) in the 10-16 age group. When biochemical
parameters are compared in terms of gender, the TG value in girls (104.9 ±
42.9) was found to be statistically significantly high compared to the TG value
for boys (68.3 ±17.2) (p<0.05). However, there was no other statistically
significant difference identified for any other biochemical parameter in terms
of gender.
Conclusion: It is
accepted that the incidence of T1DM is increasing globally and the age of
diagnosis is falling. Early diagnosis and developing effective treatment of
T1DM patients is very important in terms of preventing possible complications.
Subjects | Health Care Administration |
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Journal Section | Research articles |
Authors | |
Publication Date | August 28, 2017 |
Published in Issue | Year 2017 |