Loading [a11y]/accessibility-menu.js
Research Article
BibTex RIS Cite
Year 2019, , 26 - 32, 28.04.2019
https://doi.org/10.19127/mbsjohs.543978

Abstract

References

  • Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med 1988;15: 539–553
  • Baim DS, Grossmann W. Coronary Angiography. In: Baim Grossmann, editor. Grossman’s Cardiac Catheterization, angiography, and Intervention. 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2000; 211–57
  • Bonow RO, Smaha LA, Smith SC Jr, Mensah GA, Lenfant C. World Heart Day 2002: the international burden of cardiovascular disease: responding to the emerging global epidemic. Circulation 2002;106(13):1602-5.
  • Brown GC, Magargal LE. Central retinal artery obstruction and visual acuity. Ophthalmology. 1982;89(1):14-9.
  • Cheung N, Bluemke DA, Klein R, Sharrett AR, Islam FM, Cotch MF, Klein BE, Criqui MH, Wong TY. Retinal arteriolar narrowing and left ventricular remodeling: the multi-ethnic study of atherosclerosis. J Am Coll Cardiol. 2007;50(1):48-55.
  • Christen WG, Glynn RJ, Ajani UA, Schaumberg DA, Chew EY, Buring JE, Manson JE, Hennekens CH. Age-related maculopathy in a randomized trial of low-dose aspirin among US physicians. Arch Ophthalmol. 2001;119(8):1143-9.
  • Cymerman RM, Skolnick AH, Cole WJ, Nabati C, Curcio CA, Smith RT. Coronary Artery Disease and Reticular Macular Disease, a Subphenotype of Early Age-Related Macular Degeneration. Curr Eye Res. 2016 Nov;41(11):1482-1488.
  • David NJ, Klintworth GK, Frieldberg SJ, Dillon M. Fetal Atheromatous cerebral embolism associated with bright plaques in the retinal arterioles. Report of a case. Neurology. 1963;13:708-13
  • Del Corso L, Moruzzo D, Conte B, Agelli M, Romanelli AM, Pastine F, et al. Tortuosity, kinking, and coiling of the carotid artery: expression of atherosclerosis or aging? Angiology 1998;49: 361–71.
  • Dobrin PB, Schwarcz TH, Baker WH. Mechanism of arterial and aneurysmal tortuosity. Surgery 1988;104:568–71.
  • Ertugrul A. Diffuse tortuosity and lengthening of the arteries. Circulation 1967;36:400–7.
  • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18(6):499-502
  • Goto I, Katsuki S, Ikui H, Kimoto K, Mimatsu T. Pathological studies on the intracerebral and retinal arteries in cerebrovascular and noncerebrovascular diseases. Stroke. 1975;6(3):263-9
  • Hollenhorst RW, Lensink ER, Whisnant JP. Experimental Embolization of the Retinal Arterioles. Trans Am Ophthalmol Soc. 1962;60:316-34.
  • Hubbard LD, Brothers RJ, King WN, et al. Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology 1999; 106: 2269–2280
  • Humphrey LL, Fu R, Rogers K, et al. Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis. Mayo Clin Proc 2008;83:1203e12
  • Kelin R. Epidemiology. In age-related macular degeneration. In: Berger JW, Fine SL, Maguire MG. Eds. Philadelphia: Mosby; 1999;31–55.
  • Klein R, Klein BE, Linton KL, DeMets DL. The Beaver Dam Eye Study: the relation of age-related maculopathy to smoking. Am J Epidemiol. 1993;137(2):190-200.
  • Leipzig TJ, Dohrmann GJ. The tortuosity or kinked carotid artery: pathogenesis and clinical considerations. Surg Neurol 1986;25: 478–86.
  • Owen CG, Rudnicka AR, Nightingale CM, Mullen R, Barman SA, Sattar N, Cook DG, Whincup PH. Retinal arteriolar tortuosity and cardiovascular risk factors in a multi-ethnic population study of 10 year old children; the Child Heart And health Study in England . Arterioscler Thromb Vasc Biol. 2011 Aug;31(8):1933-8.
  • Scheie HG. Evaluation of ophthalmoscopic changes of hypertension and arteriolar sclerosis. AMA Arch Ophthalmol 1953; 49: 117–138
  • Scolari F, Bracchi M, Valzorio B, Movilli E, Costantino E, Savoldi S, Zorat S, Bonardelli S, Tardanico R, Maiorca R. Cholesterol atheromatous embolism: an increasingly recognized cause of acute renal failure. Nephrol Dial Transplant. 1996;11(8):1607-12.
  • Smith Jr SC. Current and future directions of cardiovascular risk prediction. Am J Cardiol 2006;97:28Ae32A
  • Smith W, Mitchell P, Leeder SR. Smoking and age-related maculopathy. The Blue Mountains Eye Study. Arch Ophthalmol. 1996;114(12):1518-23.
  • Soikkonen K, Wolf J, Hietanen J, Mattila K. Three main arteries of the face and their tortuosity. Br J Oral Maxillofac Surg 1991; 29:395–8.
  • Tedeschi-Reiner E, Strozzi M, Skoric B, Reiner Z. Relation of atherosclerotic changes in retinal arteries to the extent of coronary artery disease. Am J Cardiol. 2005;96(8):1107-9.
  • Torpy JM, Glass TJ, Glass RM. JAMA patient page. Retinopathy. JAMA. 2005;293(1):128.
  • Weibel J, Fields WS. Tortuosity, coiling, and kinking of the internal carotid artery: etiology and radiographic anatomy. Neurology 1965;15:7–18.
  • Wilson PW, D'Agostino RB, Levy D, et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97:1837e47
  • Wong TY, Klein R, Klein BE, Tielsch JM, Hubbard L, Nieto FJ. Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality. Surv Ophthalmol 2001; 46: 59–80.
  • Zegers ES, Meursing BT, Zegers EB, Oude Ophuis AJ. Oude Ophuis Coronary tortuosity: a long and winding road. Neth Heart J 2007;15:191–5.

Evaluation of Fundoscopic Abnormalities in Patients with Coronary Artery Disease

Year 2019, , 26 - 32, 28.04.2019
https://doi.org/10.19127/mbsjohs.543978

Abstract

Objective: Coronary artery disease (CAD) is the leading cause of death in the world.
There has been recent interest to microvasculature changes that are involved in
systemic conditions associated with CAD. Retinal microvascular changes which
can be easly detected noninvasively may be also a marker for cardiovascular
diseases. Our aim in this study was to evaluate the relationship between the
retinal findings and coronary artery disease by performing fundoscopic
examination in patients diagnosed with CAD

Methods: This study enrolled 100 patients (72 female, mean age: 59.3±7.1 years)
diagnosed with CAD, along with 100 controls (75 female, mean age: 57.8±8.2
years) who were proved to have normal coronary arteries by coronary
angiography. Bilateral fundoscopic examination was performed in all study
population. Fundoscopic findings and risk factors for CAD were compared between
the groups.

Results: There was no significant difference between the groups in terms of
clinical, demographical and laboratory characteristics of the patients. The
prevalence of atherosclerotic changes was significantly higher in patients with
CAD than controls (87 vs 58 %, p<0.001). Hypertensive retinopathy was
observed more frequently in CAD group as compared to controls (95 vs 60 %,
p<0.001). The prevalence of diabetic retinopathy, retinal vein occlusion,
retinal collateral vessels, increased retinal tortuosity, Drusenoid bodies and
Hollenhorst plaques were similar between the groups.







Conclusion: The atherosclerotic and hypertensive retinal findings were more frequently
observed in patients with coronary artery disease. Therefore, fundoscopic
examination may be useful in the evaluation of such patients with coronary
artery disease.


References

  • Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med 1988;15: 539–553
  • Baim DS, Grossmann W. Coronary Angiography. In: Baim Grossmann, editor. Grossman’s Cardiac Catheterization, angiography, and Intervention. 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2000; 211–57
  • Bonow RO, Smaha LA, Smith SC Jr, Mensah GA, Lenfant C. World Heart Day 2002: the international burden of cardiovascular disease: responding to the emerging global epidemic. Circulation 2002;106(13):1602-5.
  • Brown GC, Magargal LE. Central retinal artery obstruction and visual acuity. Ophthalmology. 1982;89(1):14-9.
  • Cheung N, Bluemke DA, Klein R, Sharrett AR, Islam FM, Cotch MF, Klein BE, Criqui MH, Wong TY. Retinal arteriolar narrowing and left ventricular remodeling: the multi-ethnic study of atherosclerosis. J Am Coll Cardiol. 2007;50(1):48-55.
  • Christen WG, Glynn RJ, Ajani UA, Schaumberg DA, Chew EY, Buring JE, Manson JE, Hennekens CH. Age-related maculopathy in a randomized trial of low-dose aspirin among US physicians. Arch Ophthalmol. 2001;119(8):1143-9.
  • Cymerman RM, Skolnick AH, Cole WJ, Nabati C, Curcio CA, Smith RT. Coronary Artery Disease and Reticular Macular Disease, a Subphenotype of Early Age-Related Macular Degeneration. Curr Eye Res. 2016 Nov;41(11):1482-1488.
  • David NJ, Klintworth GK, Frieldberg SJ, Dillon M. Fetal Atheromatous cerebral embolism associated with bright plaques in the retinal arterioles. Report of a case. Neurology. 1963;13:708-13
  • Del Corso L, Moruzzo D, Conte B, Agelli M, Romanelli AM, Pastine F, et al. Tortuosity, kinking, and coiling of the carotid artery: expression of atherosclerosis or aging? Angiology 1998;49: 361–71.
  • Dobrin PB, Schwarcz TH, Baker WH. Mechanism of arterial and aneurysmal tortuosity. Surgery 1988;104:568–71.
  • Ertugrul A. Diffuse tortuosity and lengthening of the arteries. Circulation 1967;36:400–7.
  • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18(6):499-502
  • Goto I, Katsuki S, Ikui H, Kimoto K, Mimatsu T. Pathological studies on the intracerebral and retinal arteries in cerebrovascular and noncerebrovascular diseases. Stroke. 1975;6(3):263-9
  • Hollenhorst RW, Lensink ER, Whisnant JP. Experimental Embolization of the Retinal Arterioles. Trans Am Ophthalmol Soc. 1962;60:316-34.
  • Hubbard LD, Brothers RJ, King WN, et al. Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology 1999; 106: 2269–2280
  • Humphrey LL, Fu R, Rogers K, et al. Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis. Mayo Clin Proc 2008;83:1203e12
  • Kelin R. Epidemiology. In age-related macular degeneration. In: Berger JW, Fine SL, Maguire MG. Eds. Philadelphia: Mosby; 1999;31–55.
  • Klein R, Klein BE, Linton KL, DeMets DL. The Beaver Dam Eye Study: the relation of age-related maculopathy to smoking. Am J Epidemiol. 1993;137(2):190-200.
  • Leipzig TJ, Dohrmann GJ. The tortuosity or kinked carotid artery: pathogenesis and clinical considerations. Surg Neurol 1986;25: 478–86.
  • Owen CG, Rudnicka AR, Nightingale CM, Mullen R, Barman SA, Sattar N, Cook DG, Whincup PH. Retinal arteriolar tortuosity and cardiovascular risk factors in a multi-ethnic population study of 10 year old children; the Child Heart And health Study in England . Arterioscler Thromb Vasc Biol. 2011 Aug;31(8):1933-8.
  • Scheie HG. Evaluation of ophthalmoscopic changes of hypertension and arteriolar sclerosis. AMA Arch Ophthalmol 1953; 49: 117–138
  • Scolari F, Bracchi M, Valzorio B, Movilli E, Costantino E, Savoldi S, Zorat S, Bonardelli S, Tardanico R, Maiorca R. Cholesterol atheromatous embolism: an increasingly recognized cause of acute renal failure. Nephrol Dial Transplant. 1996;11(8):1607-12.
  • Smith Jr SC. Current and future directions of cardiovascular risk prediction. Am J Cardiol 2006;97:28Ae32A
  • Smith W, Mitchell P, Leeder SR. Smoking and age-related maculopathy. The Blue Mountains Eye Study. Arch Ophthalmol. 1996;114(12):1518-23.
  • Soikkonen K, Wolf J, Hietanen J, Mattila K. Three main arteries of the face and their tortuosity. Br J Oral Maxillofac Surg 1991; 29:395–8.
  • Tedeschi-Reiner E, Strozzi M, Skoric B, Reiner Z. Relation of atherosclerotic changes in retinal arteries to the extent of coronary artery disease. Am J Cardiol. 2005;96(8):1107-9.
  • Torpy JM, Glass TJ, Glass RM. JAMA patient page. Retinopathy. JAMA. 2005;293(1):128.
  • Weibel J, Fields WS. Tortuosity, coiling, and kinking of the internal carotid artery: etiology and radiographic anatomy. Neurology 1965;15:7–18.
  • Wilson PW, D'Agostino RB, Levy D, et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97:1837e47
  • Wong TY, Klein R, Klein BE, Tielsch JM, Hubbard L, Nieto FJ. Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality. Surv Ophthalmol 2001; 46: 59–80.
  • Zegers ES, Meursing BT, Zegers EB, Oude Ophuis AJ. Oude Ophuis Coronary tortuosity: a long and winding road. Neth Heart J 2007;15:191–5.
There are 31 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Research articles
Authors

Tolga Doğan 0000-0003-1281-942X

Macit Kalçık 0000-0002-8791-4475

Mucahit Yetim This is me 0000-0002-2444-7523

Özgür Yalçınbayır This is me 0000-0003-0263-0439

Lütfü Bekar 0000-0002-3920-1382

Oğuzhan Çelik This is me 0000-0001-7841-0227

Osman Akın Serdar 0000-0003-3529-5649

Publication Date April 28, 2019
Published in Issue Year 2019

Cite

Vancouver Doğan T, Kalçık M, Yetim M, Yalçınbayır Ö, Bekar L, Çelik O, Serdar OA. Evaluation of Fundoscopic Abnormalities in Patients with Coronary Artery Disease. Mid Blac Sea J Health Sci. 2019;5(1):26-32.

2310022108  22107  22106  22105  22103  22109 22137 22102  22110    e-ISSN 2149-7796