The Relationship Between Body Mass Index and Lower Urinary Tract Symptoms in Men
Abstract
Objective: The studies evaluating, association between obesity and lower urinary tract symptoms (LUTS) are limited. Our study’s objective was to determine the correlation between obesity and LUTS in men.
Methods: Information of 639 patients who were aged between 37 and 92, had not been treated for BPH before, had moderate or severe LUTS, had International Prostate Symptom Score (IPSS) ≥8 and had prostate-specific antigen (PSA) value less than 4 ng/ml was evaluated retrospectively. Measured Body Mass Index (BMI) was classified in accordance with World Health Organization (WHO).
Results: A statistically significant difference was present between BMI groups with respect to post-void residual urine volume (PVR) (p=0.017). PVR level of the obesity group’s PVR level was found to be significantly lower when compared to the normal group (p<0.05). In patients with diabetes mellitus (DM), only PVR parameter among LUTS was found to differ significantly from BMI groups (p=0.037). In patients with DM, the mean of PVR of obese patients was detected to be significantly lower when compared to the mean of normal patients (p<0.05). In patients with cardiovascular disease (CD), only Qmax and Qave parameters were found to differ significantly from BMI groups. (p=0.001 and p<0.001, respectively). In patients with CD, the mean Qmax of obese patients was significantly higher than the average of normal-weight patients (p<0.05).
Conclusion: Although there is no association between obesity and LUTS except PVR, we think that the risk of obesity associated with DM and CD would significantly increase the risk of LUTS.
Keywords
Lower urinary tract symptoms,Body mass index,Obesity,Urology
References
- Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, et al. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub‐committee of the International Continence Society. Neurourol Urodynam. 2002;21(2):167-78.
- Altunkaynak BZ, Ozbek E. Obesity: Causes And Treatment Alternatives. Van Med J. 2006;13(4):138-42.
- Barqawi AB, Golden BK, O'Donnell C, Brawer MK, Crawford ED. Observed effect of age and body mass index on total and complexed PSA: analysis from a national screening program. Urology. 2005;65(4):708-12.
- Bart S, Ciangura C, Thibault F, Cardot V, Richard F, Basdevant A, et al. Stress urinary incontinence and obesity. Prog Urol. 2008;18(8):493-8.
- Bilge C, Beji NK. Obesity and Lower Urinary Tract Symptoms in Women. Florence Nightingale J Nurs. 2016;24(2):72-9.
- Chapple CR, Roehrborn CG. A shifted paradigm for the further understanding, evaluation, and treatment of lower urinary tract symptoms in men: focus on the bladder. Eur Urol. 2006;49(4):651-8.
- Cetinkaya M, Oztekin V. Benign prostatic hyperplasia and heredity. Bull Urooncol. 2011;4:20-2.
- Dahle SE, Chokkalingam AP, Gao YT, Deng J, Stanczyk FZ, Hsing AW. Body size and serum levels of insulin and leptin in relation to the risk of benign prostatic hyperplasia. J Urol. 2002;168(2):599-604.
- Fitzgerald MP, Link CL, Litman HJ, Travison TG, McKinlay JB. Beyond the lower urinary tract: the association of urologic and sexual symptoms with common illnesses. Eur Urol. 2007;52(2):407-15.
- Gann PH, Hennekens CH, Grodstein F, Stampfer MJ, Longcope C, Verhoek‐Oftedahl W. A prospective study of plasma hormone levels, nonhormonal factors, and development of benign prostatic hyperplasia. Prostate. 1995;26(1):40-9.