Research Article

Demodex spp Distribution in Patients with Alcohol Abuse

Volume: 5 Number: 3 December 31, 2019
EN

Demodex spp Distribution in Patients with Alcohol Abuse

Abstract

Objective: Demodex is an ectoparasite that can infest the human body. The infestation can progress rapidly when the immune system is suppressed. The condition has also been reported to be more common in subjects with alcohol abuse because of the associated immune system abnormalities and decreased hygiene. Our aim in this study was to determine whether a relationship was present between Demodex spp. infestation and alcohol abuse

Methods: A total of 26 patients diagnosed with alcohol abuse according to DSM-5 at the psychiatry outpatient department and 24 age- and gender-matched healthy volunteers who met the study inclusion criteria were included in the study. A standard superficial skin biopsy (SSSB) was used in the diagnosis of Demodex folliculorum. The compliance of the numeric variables with the normal distribution was investigated with the Shapiro-Wilk test. The data were presented as mean, standard deviation and percentages

Results. A significant relationship was found between Demodex presence and alcohol abuse (p=0.001). The relationship was also significant when patients with both alcohol abuse and smoking were investigated (p<0.001).

Conclusion: The Demodex spp. infestation incidence may be increased in patients with alcohol abuse. We recommend providing the relevant treatment especially for erythematous and itchy facial lesions in these patients as Demodex spp. can be opportunistic pathogens.

Keywords

Demodex,Alcohol abuse,smoking,addiction and demodex

References

  1. Akdeniz S, Bahceci M, AK Tuzcu, Harman M, Alp S, Bahceci S. İs demodex folliculorum larger in diabetic patients?. J Europ Acad Dermatol Venereol 2002;16 (5): 539.
  2. Akilov OE, Mumcuoglu KY. İmmune response in demodicidosis. J Eur Acad Dermatol Venereol 2004;18:440-4.
  3. Aquilina C, Viraben R, Sire S. Ivermectin-responsive Demodex infestation during human immunodeficiency virus infection. Dermatology 2002 205:394-7.
  4. Aycan O, Otlu H, Karaman U, Daldal N, Atambay M. Frequency of Demodicosis in Various Patient and Age Groups. Turkish Society for Parasitology. 2007;31:1158.
  5. Bastemir S, Ermertcan A, Nese N, Aydogdu İ, Yereli K, Ozbilgin A. Hodgkin Lenfomali Bir Hastada Demodex folliculorum Enfestasyonu: Bir Olgu Sunumu. Turk Mikrobiyol Cem Derg 2015; 45(3):149-152
  6. Chovatiya RJ, Colegio OR. Demodicosis in renal transplant recipients. Am J Transplant 2016;16:712-6.
  7. Ciftci IH, Dundar U, Cetinkaya Z, Kulas M, Kiyildi N, Turel A, et al. Demodex folliculorum in patients with rheumatoid arthritis. Acta Parasitol 2007;52: 70-3
  8. Crews FT, Bechara R, Brown LA, Guidot DM, Mandrekar P, Oak S et al. Cytokines and alcohol. Alcohol Clin Exp Res. 2006;30:720–30.
  9. Crews FT, Bechara R, Brown LA, Guidot DM, Mandrekar P, Oak S et al. Cytokines and alcohol. Alcohol Clin Exp Res. 2006;30:720–30.
  10. Demirdag HG, Ozcan H, Gursoy S. The effects of sebum configuration on Demodex spp. density. Turk J Med Sci 2016; 46: 1-7
Vancouver
1.Serpil Şener, Ulku Karaman, Nihal Altunışık, Gülbahar Saraç, Hatice Cumurcu, Gülden Hakverdi. Demodex spp Distribution in Patients with Alcohol Abuse. Mid Blac Sea J Health Sci. 2019 Dec. 1;5(3):246-51. doi:10.19127/mbsjohs.655707