Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2021, Cilt: 7 Sayı: 2, 192 - 197, 31.08.2021
https://doi.org/10.19127/mbsjohs.899345

Öz

Kaynakça

  • 1. Leidig-Bruckner G, Hosch S, Dodidou P, Ritschel D, Conradt C, Klose C, et al. Frequency and predictors of osteoporotic fractures after cardiac or liver transplantation: a follow-up study. The Lancet. 2001;357(9253):342-7.
  • 2. Guichelaar MM, Schmoll J, Malinchoc M, Hay JE. Fractures and avascular necrosis before and after orthotopic liver transplantation: long‐term follow‐up and predictive factors. Hepatology. 2007;46(4):1198-207.
  • 3. Leslie WD, Bernstein CN, Leboff MS. AGA technical review on osteoporosis in hepatic disorders. Gastroenterology. 2003;125(3):941-66.
  • 4. Guichelaar MM, Kendall R, Malinchoc M, Hay JE. Bone mineral density before and after OLT: long‐term follow‐up and predictive factors. Liver transplantation. 2006;12(9):1390-402.
  • 5. Gallego‐Rojo FJ, Gonzalez‐Calvin JL, Muñoz‐Torres M, Mundi JL, Fernandez‐Perez R, Rodrigo‐Moreno D. Bone mineral density, serum insulin‐like growth factor I, and bone turnover markers in viral cirrhosis. Hepatology. 1998;28(3):695-9.
  • 6. Ninkovic M, Skingle SJ, Bearcroft P, Bishop N, Alexander G, Compston JE. Incidence of vertebral fractures in the first three months after orthotopic liver transplantation. European journal of gastroenterology & hepatology. 2000;12(8):931-5. 7. Segal E, Baruch Y, Kramsky R, Raz B, Tamir A, Ish‐Shalom S. Predominant factors associated with bone loss in liver transplant patients–after prolonged post‐transplantation period. Clinical transplantation. 2003;17(1):13-9.
  • 8. Denis F: The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine. 1983;8(8):817-831.
  • 9. Collier J. Bone disorders in chronic liver disease. Hepatology. 2007;46(4):1271-8.
  • 10. Butin S, Griffoul I, Espitalier F, Salamé E, Mulleman D, Goupille P. High incidence of vertebral osteoporotic fracture within the first year after liver transplantation. Clin Exp Rheumatol. 2017;35(6):913-8.
  • 11. Muschitz C, Kocijan R, Haschka J, Pahr D, Kaider A, Pietschmann P, et al. TBS reflects trabecular microarchitecture in premenopausal women and men with idiopathic osteoporosis and low-traumatic fractures. Bone. 2015;79:259-66.
  • 12. Pérez-Sáez MJ, Herrera S, Prieto-Alhambra D, Vilaplana L, Nogués X, Vera M, et al. Bone density, microarchitecture, and material strength in chronic kidney disease patients at the time of kidney transplantation. Osteoporosis International. 2017;28(9):2723-7.
  • 13. Kim JH, Choi HJ, Ku EJ, Kim KM, Kim SW, Cho NH, et al. Trabecular bone score as an indicator for skeletal deterioration in diabetes. The Journal of Clinical Endocrinology & Metabolism. 2015;100(2):475-82.
  • 14. Wakolbinger R, Muschitz C, Scheriau G, Bodlaj G, Kocijan R, Feichtinger X, et al. Bone microarchitecture and bone turnover in hepatic cirrhosis. Osteoporosis International. 2019;30(6):1195-204.
  • 15. Leslie WD, Morin SN. New Developments in Fracture Risk Assessment for Current Osteoporosis Reports. Current osteoporosis reports. 2020;18(3):115-29.
  • 16. Kayanja M, Evans K, Milks R, Lieberman IH. The mechanics of polymethylmethacrylate augmentation. Clinical Orthopaedics and Related Research®. 2006;443:124-30.
  • 17. Kayanja MM, Schlenk R, Togawa D, Ferrara L, Lieberman I. The biomechanics of 1, 2, and 3 levels of vertebral augmentation with polymethylmethacrylate in multilevel spinal segments. Spine. 2006;31(7):769-74.
  • 18. Li X, Lu Y, Lin X. Refracture of osteoporotic vertebral body after treatment by balloon kyphoplasty: Three cases report. Medicine. 2017;96(49).
  • 19. Zhang W, Chen C, Zhang C, Duan J, Li Y, Ma H, et al. Probing the binding interaction of terbinafine with human serum albumin via multiple fluorescence spectroscopy and molecular modeling. Lat Am J Pharm. 2016;35(6):1399-406.
  • 20. Lee HM, Park SY, Lee SH, Suh SW, Hong JY. Comparative analysis of clinical outcomes in patients with osteoporotic vertebral compression fractures (OVCFs): conservative treatment versus balloon kyphoplasty. The Spine Journal. 2012;12(11):998-1005.
  • 21. Wang H-K, Lu K, Liang C-L, Weng H-C, Wang K-W, Tsai Y-D, et al. Comparing clinical outcomes following percutaneous vertebroplasty with conservative therapy for acute osteoporotic vertebral compression fractures. Pain medicine. 2010;11(11):1659-65.
  • 22. Buchbinder R, Johnston RV, Rischin KJ, Homik J, Jones CA, Golmohammadi K, et al. Percutaneous vertebroplasty for osteoporotic vertebral compression fracture. Cochrane Database of Systematic Reviews. 2018(11).

Management of Stabil Vertebra Fractures in Patients Underwent Liver Transplantation

Yıl 2021, Cilt: 7 Sayı: 2, 192 - 197, 31.08.2021
https://doi.org/10.19127/mbsjohs.899345

Öz

Objective: Bone mineral density decreases after liver transplantation, and the incidence of vertebral fracture concerning this increase. Vertebral fractures due to bone mineral density increase mortality due to pain, spinal deformity, neurological deficit, and immobility. This study discussed the patients with a vertebral fracture who underwent liver transplantation and received kyphoplasty and conservative treatments to reference clinical treatments.

Methods: Among the 2200 patients who underwent liver transplantation between 2002-2020, 65 of the 110 patients underwent spinal Magnetic Resonance Imaging (MRI), and computed tomography (CT) due to back and low back pain had vertebral fractures. Of these 65 patients, 48 were unstable, and 17 were stable vertebral fractures. Patients with stable vertebral fractures were grouped as conservative (n=9) and balloon kyphoplasty (n=8), as these groups compared the following parameters: age, sex, bone densitometry, laboratory findings (Ca, P), vertebral fracture levels, cigarette, high blood pressure, alcohol use, pre-operation, and post-operation 20th-day Visual Analogue Scale scores.

Results: While there were no significant differences between the VAS score and the VAS score after 20 days in the patients who received conservative treatment, a significant difference was found between the VAS score and the VAS score after 20 days in the patients who received kyphoplasty.

Conclusion: It disrupts patient compliance in treating the primary disease due to pain and immobilization in patients who received organ transplantation, and increases the complications due to immobilization. Therefore, performing kyphoplasty is recommended in symptomatic vertebral fractures that do not require stabilization after organ transplantation regardless of the VAS score.

Kaynakça

  • 1. Leidig-Bruckner G, Hosch S, Dodidou P, Ritschel D, Conradt C, Klose C, et al. Frequency and predictors of osteoporotic fractures after cardiac or liver transplantation: a follow-up study. The Lancet. 2001;357(9253):342-7.
  • 2. Guichelaar MM, Schmoll J, Malinchoc M, Hay JE. Fractures and avascular necrosis before and after orthotopic liver transplantation: long‐term follow‐up and predictive factors. Hepatology. 2007;46(4):1198-207.
  • 3. Leslie WD, Bernstein CN, Leboff MS. AGA technical review on osteoporosis in hepatic disorders. Gastroenterology. 2003;125(3):941-66.
  • 4. Guichelaar MM, Kendall R, Malinchoc M, Hay JE. Bone mineral density before and after OLT: long‐term follow‐up and predictive factors. Liver transplantation. 2006;12(9):1390-402.
  • 5. Gallego‐Rojo FJ, Gonzalez‐Calvin JL, Muñoz‐Torres M, Mundi JL, Fernandez‐Perez R, Rodrigo‐Moreno D. Bone mineral density, serum insulin‐like growth factor I, and bone turnover markers in viral cirrhosis. Hepatology. 1998;28(3):695-9.
  • 6. Ninkovic M, Skingle SJ, Bearcroft P, Bishop N, Alexander G, Compston JE. Incidence of vertebral fractures in the first three months after orthotopic liver transplantation. European journal of gastroenterology & hepatology. 2000;12(8):931-5. 7. Segal E, Baruch Y, Kramsky R, Raz B, Tamir A, Ish‐Shalom S. Predominant factors associated with bone loss in liver transplant patients–after prolonged post‐transplantation period. Clinical transplantation. 2003;17(1):13-9.
  • 8. Denis F: The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine. 1983;8(8):817-831.
  • 9. Collier J. Bone disorders in chronic liver disease. Hepatology. 2007;46(4):1271-8.
  • 10. Butin S, Griffoul I, Espitalier F, Salamé E, Mulleman D, Goupille P. High incidence of vertebral osteoporotic fracture within the first year after liver transplantation. Clin Exp Rheumatol. 2017;35(6):913-8.
  • 11. Muschitz C, Kocijan R, Haschka J, Pahr D, Kaider A, Pietschmann P, et al. TBS reflects trabecular microarchitecture in premenopausal women and men with idiopathic osteoporosis and low-traumatic fractures. Bone. 2015;79:259-66.
  • 12. Pérez-Sáez MJ, Herrera S, Prieto-Alhambra D, Vilaplana L, Nogués X, Vera M, et al. Bone density, microarchitecture, and material strength in chronic kidney disease patients at the time of kidney transplantation. Osteoporosis International. 2017;28(9):2723-7.
  • 13. Kim JH, Choi HJ, Ku EJ, Kim KM, Kim SW, Cho NH, et al. Trabecular bone score as an indicator for skeletal deterioration in diabetes. The Journal of Clinical Endocrinology & Metabolism. 2015;100(2):475-82.
  • 14. Wakolbinger R, Muschitz C, Scheriau G, Bodlaj G, Kocijan R, Feichtinger X, et al. Bone microarchitecture and bone turnover in hepatic cirrhosis. Osteoporosis International. 2019;30(6):1195-204.
  • 15. Leslie WD, Morin SN. New Developments in Fracture Risk Assessment for Current Osteoporosis Reports. Current osteoporosis reports. 2020;18(3):115-29.
  • 16. Kayanja M, Evans K, Milks R, Lieberman IH. The mechanics of polymethylmethacrylate augmentation. Clinical Orthopaedics and Related Research®. 2006;443:124-30.
  • 17. Kayanja MM, Schlenk R, Togawa D, Ferrara L, Lieberman I. The biomechanics of 1, 2, and 3 levels of vertebral augmentation with polymethylmethacrylate in multilevel spinal segments. Spine. 2006;31(7):769-74.
  • 18. Li X, Lu Y, Lin X. Refracture of osteoporotic vertebral body after treatment by balloon kyphoplasty: Three cases report. Medicine. 2017;96(49).
  • 19. Zhang W, Chen C, Zhang C, Duan J, Li Y, Ma H, et al. Probing the binding interaction of terbinafine with human serum albumin via multiple fluorescence spectroscopy and molecular modeling. Lat Am J Pharm. 2016;35(6):1399-406.
  • 20. Lee HM, Park SY, Lee SH, Suh SW, Hong JY. Comparative analysis of clinical outcomes in patients with osteoporotic vertebral compression fractures (OVCFs): conservative treatment versus balloon kyphoplasty. The Spine Journal. 2012;12(11):998-1005.
  • 21. Wang H-K, Lu K, Liang C-L, Weng H-C, Wang K-W, Tsai Y-D, et al. Comparing clinical outcomes following percutaneous vertebroplasty with conservative therapy for acute osteoporotic vertebral compression fractures. Pain medicine. 2010;11(11):1659-65.
  • 22. Buchbinder R, Johnston RV, Rischin KJ, Homik J, Jones CA, Golmohammadi K, et al. Percutaneous vertebroplasty for osteoporotic vertebral compression fracture. Cochrane Database of Systematic Reviews. 2018(11).
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makaleleri
Yazarlar

Ramazan Paşahan 0000-0002-3221-1422

Bora Tetik 0000-0001-7696-7785

Emek Güldoğan 0000-0002-5436-8164

Adil Başkıran Bu kişi benim 0000-0002-7536-1631

Sezai Yılmaz 0000-0002-8044-0297

Yayımlanma Tarihi 31 Ağustos 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 7 Sayı: 2

Kaynak Göster

Vancouver Paşahan R, Tetik B, Güldoğan E, Başkıran A, Yılmaz S. Management of Stabil Vertebra Fractures in Patients Underwent Liver Transplantation. Middle Black Sea Journal of Health Science. 2021;7(2):192-7.

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