Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2021, Cilt: 7 Sayı: 2, 198 - 204, 31.08.2021
https://doi.org/10.19127/mbsjohs.946172

Öz

Kaynakça

  • 1. Masri A, Jaafar A, Noman R, Gharaibeh A, Ababneh OH. Intracranial hypertension in children: Etiologies, clinical features, and outcome. J Child Neurol .2015;30(12):1562–8.
  • 2. Standridge SM. Idiopathic intracranial hypertension in children: A review and algorithm. Pediatric Neurology. Pediatr Neurol; 2010;43: 377–90.
  • 3. Friedman DI, Liu GT, Digre KB. Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children Neurology. Neurology; 2013;81:1159–65.
  • 4. Spennato P, Ruggiero C, Parlato RS, Buonocore MC, Varone A, Cianciulli E, et al. Pseudotumor cerebri. Child’s Nervous System. Childs Nerv Syst; 2011;27:215–35.
  • 5. Cleves-Bayon C. Idiopathic Intracranial Hypertension in Children and Adolescents: An Update. Headache .2018;58(3):485–93.
  • 6. Phillips PH, Sheldon CA. Pediatric Pseudotumor Cerebri Syndrome. Journal of neuro-ophthalmology: the official journal of the North American Neuro-Ophthalmology Society. J Neuroophthalmol; 2017;37:33–40.
  • 7. Salpietro V, Polizzi A, Bertè LF, Chimenz R, Chirico V, Ferraù V, et al.,Idiopathic intracranial hypertension: a unifying neuroendocrine hypothesis through the adrenal-brain axis. Neuroendocrinol Lett 2012; 33(6): 101–5.
  • 8. Tibussek D, Distelmaier F, Karenfort M, Harmsen S, Klee D, Mayatepek E. Probable pseudotumor cerebri complex in 25 children. Further support of a concept. Eur J Paediatr Neurol .2017;21(2):280–5.
  • 9. Tibussek D, Schneider DT, Vandemeulebroecke N, Turowski B, Messing-Juenger M, Willems PHGM, et al. Clinical spectrum of the pseudotumor cerebri complex in children. Child’s Nerv Syst .2010;26(3):313–21. 10.Balcer LJ, Liu GT, Forman S, Pun K, Volpe NJ, Galetta SL, et al. Idiopathic intracranial hypertension: Relation of age and obesity in children. Neurology .1999;52(4):870–2.
  • 11.Friedman DI, Jacobson DM. Idiopathic intracranial hypertension. Journal of Neuro-Ophthalmology. J Neuroophthalmol; 2004;24:138–45.
  • 12. Per H, Canpolat M, G um us H, Poyrazoĝlu HG, Yikilmaz A, Karak uc uk S, et al. Clinical spectrum of the pseudotumor cerebri in children: Etiological, clinical features, treatment, and prognosis. Brain Dev .2013;35(6):561–8.
  • 13. Wall M, Kupersmith MJ, Kieburtz KD, Corbett JJ, Feldon SE, Friedman DI, et al. The idiopathic intracranial hypertension treatment trial clinical profile at baseline. JAMA Neurol .2014;71(6):693–701.
  • 14. Corbett JJ, Savino PJ, Thompson HS, Kansu T, Schatz NJ, Orr LS, et al. Visual Loss in Pseudotumor Cerebri: Follow-up of 57 Patients from Five to 41 Years and a Profile of 14 Patients with Permanent Severe Visual Loss. Arch Neurol .1982;39(8):461–74.
  • 15.Oguz MM, Polat E. Pediatric Pseudotumor Cerebri Syndrome with Etiological and Clinical Features. Firat University Medical Journal of Health Sciences. 2019; 33 (1): 15-9.
  • 16.Goksan B. A guidebook on the approach to neurological diseases in children and adolescents. 2015. The child and adolescent neurology study group. Editors: Aysin DERVENT, Semih AYTA, Ozlem COKAR. pp 371-4.
  • 17.Distelmaier F, Sengler U, Messing-Juenger M, Assmann B, Mayatepek E, Rosenbaum T. Pseudotumor cerebri as an important differential diagnosis of papilledema in children. Brain Dev. 2006;28(3):190–5.
  • 18.Distelmaier F, Tibussek D, Schneider DT, Mayatepek E. Seasonal variation and atypical presentation of idiopathic intracranial hypertension in pre-pubertal children. Cephalalgia .2007;27(11):1261–4.
  • 19.Lin A, Foroozan R, Danesh-Meyer H V., De Salvo G, Savino PJ, Sergott RC. Occurrence of Cerebral Venous Sinus Thrombosis in Patients with Presumed Idiopathic Intracranial Hypertension.Ophthalmology. 2006;113(12):2281–4.
  • 20. Benzimra JD, Simon S, Sinclair AJ, Mollan SP. Sight-Threatening pseudotumour cerebri associated with excess vitamin a supplementation. Pract Neurol .2015;15(1):72–3. 21.Lessell S. Pediatric pseudotumor cerebri (idiopathic intracranial hypertension). Survey of Ophthalmology. Surv Ophthalmol; 1992;37:155–66.
  • 22.Henry M, Driscoll MC, Miller M, Chang T, Minniti CP. Pseudotumor cerebri in children with sickle cell disease: a case series. Pediatrics 2004;113: 265-69.
  • 23.Avery RA, Shah SS, Licht DJ, Seiden JA, Huh JW, Boswinkel J, et al. Reference Range for Cerebrospinal Fluid Opening Pressure in Children. N Engl J Med .2010;363(9):891–3.
  • 24.Gospe SM, Bhatti MT, El-Dairi MA. Anatomic and visual function outcomes in paediatric idiopathic intracranial hypertension. Br J Ophthalmol .2016;100(4):505–9.
  • 25.Deǧerliyurt A, Teber S, Karakaya G, G uven A, Seker ED, Arhan EP, et al. Pseudotumor cerebri/idiopathic intracranial hypertension in children: An experience of a tertiary care hospital. Brain Dev .2014;36(8):690–9.
  • 26.Gocmen R, Konuskan B. Clinical and neurogoral findings of pseudotic umor cerebr in children. Kirikkale University Faculty of Medicine Journal. 2018 Apr 30 ;20(1):33–40.
  • .

Etiological Factors in Pediatric Pseudotumor Cerebri Cases

Yıl 2021, Cilt: 7 Sayı: 2, 198 - 204, 31.08.2021
https://doi.org/10.19127/mbsjohs.946172

Öz

Objective: Pseudotumor cerebri (PTC) is the presence of the signs and symptoms of intracranial pressure increase in the absence of a tumoral, structural or vascular mass-occupying lesion. This study aimed to investigate the etiological factors involved in childhood PTC cases.

Methods: Data of the patients presented to the Private Medical Park Samsun Hospital, pediatric neurology outpatient clinic with the preliminary diagnosis of PTC between June 2015 and December 2020 were retrospectively reviewed. Demographic data, presentation symptoms, neuro-ophthalmological examination findings, laboratory data, and radiological imaging (brain magnetic resonance imaging, magnetic resonance venography) findings. The female (i.e., Group 1) and male (i.e., Group 2) children were compared concerning the etiological factors.

Results: The study cohort included 45 patients. There were 24 patients in Group 1 (i.e., female children) and 21 patients in Group 2 (i.e., male children). Among the 45 patients, 41 (91.1%) had an overt etiological factor. Mean age of the study patients were 9.06 year [2,5 months-18 years]. The most common symptom was headache (64.4%). Two groups were similar concerning mean patient age, pubertal stage, and rates of vitamin B12 deficiency, iron deficiency anemia, vitamin D deficiency, abnormal brain magnetic resonance imaging, and magnetic resonance venography findings. However, the obesity rate was significantly higher in Group 2 than Group 1 (32,7% vs. 12,5%, p<0.05).

Conclusion: A thorough investigation concerning etiology is crucial in pediatric PTC cases regardless of patient gender. Timely investigations regarding etiology will lead to timely treatment of this clinical condition and prevent irreversible devastating complications such as permanent hearing loss.

Kaynakça

  • 1. Masri A, Jaafar A, Noman R, Gharaibeh A, Ababneh OH. Intracranial hypertension in children: Etiologies, clinical features, and outcome. J Child Neurol .2015;30(12):1562–8.
  • 2. Standridge SM. Idiopathic intracranial hypertension in children: A review and algorithm. Pediatric Neurology. Pediatr Neurol; 2010;43: 377–90.
  • 3. Friedman DI, Liu GT, Digre KB. Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children Neurology. Neurology; 2013;81:1159–65.
  • 4. Spennato P, Ruggiero C, Parlato RS, Buonocore MC, Varone A, Cianciulli E, et al. Pseudotumor cerebri. Child’s Nervous System. Childs Nerv Syst; 2011;27:215–35.
  • 5. Cleves-Bayon C. Idiopathic Intracranial Hypertension in Children and Adolescents: An Update. Headache .2018;58(3):485–93.
  • 6. Phillips PH, Sheldon CA. Pediatric Pseudotumor Cerebri Syndrome. Journal of neuro-ophthalmology: the official journal of the North American Neuro-Ophthalmology Society. J Neuroophthalmol; 2017;37:33–40.
  • 7. Salpietro V, Polizzi A, Bertè LF, Chimenz R, Chirico V, Ferraù V, et al.,Idiopathic intracranial hypertension: a unifying neuroendocrine hypothesis through the adrenal-brain axis. Neuroendocrinol Lett 2012; 33(6): 101–5.
  • 8. Tibussek D, Distelmaier F, Karenfort M, Harmsen S, Klee D, Mayatepek E. Probable pseudotumor cerebri complex in 25 children. Further support of a concept. Eur J Paediatr Neurol .2017;21(2):280–5.
  • 9. Tibussek D, Schneider DT, Vandemeulebroecke N, Turowski B, Messing-Juenger M, Willems PHGM, et al. Clinical spectrum of the pseudotumor cerebri complex in children. Child’s Nerv Syst .2010;26(3):313–21. 10.Balcer LJ, Liu GT, Forman S, Pun K, Volpe NJ, Galetta SL, et al. Idiopathic intracranial hypertension: Relation of age and obesity in children. Neurology .1999;52(4):870–2.
  • 11.Friedman DI, Jacobson DM. Idiopathic intracranial hypertension. Journal of Neuro-Ophthalmology. J Neuroophthalmol; 2004;24:138–45.
  • 12. Per H, Canpolat M, G um us H, Poyrazoĝlu HG, Yikilmaz A, Karak uc uk S, et al. Clinical spectrum of the pseudotumor cerebri in children: Etiological, clinical features, treatment, and prognosis. Brain Dev .2013;35(6):561–8.
  • 13. Wall M, Kupersmith MJ, Kieburtz KD, Corbett JJ, Feldon SE, Friedman DI, et al. The idiopathic intracranial hypertension treatment trial clinical profile at baseline. JAMA Neurol .2014;71(6):693–701.
  • 14. Corbett JJ, Savino PJ, Thompson HS, Kansu T, Schatz NJ, Orr LS, et al. Visual Loss in Pseudotumor Cerebri: Follow-up of 57 Patients from Five to 41 Years and a Profile of 14 Patients with Permanent Severe Visual Loss. Arch Neurol .1982;39(8):461–74.
  • 15.Oguz MM, Polat E. Pediatric Pseudotumor Cerebri Syndrome with Etiological and Clinical Features. Firat University Medical Journal of Health Sciences. 2019; 33 (1): 15-9.
  • 16.Goksan B. A guidebook on the approach to neurological diseases in children and adolescents. 2015. The child and adolescent neurology study group. Editors: Aysin DERVENT, Semih AYTA, Ozlem COKAR. pp 371-4.
  • 17.Distelmaier F, Sengler U, Messing-Juenger M, Assmann B, Mayatepek E, Rosenbaum T. Pseudotumor cerebri as an important differential diagnosis of papilledema in children. Brain Dev. 2006;28(3):190–5.
  • 18.Distelmaier F, Tibussek D, Schneider DT, Mayatepek E. Seasonal variation and atypical presentation of idiopathic intracranial hypertension in pre-pubertal children. Cephalalgia .2007;27(11):1261–4.
  • 19.Lin A, Foroozan R, Danesh-Meyer H V., De Salvo G, Savino PJ, Sergott RC. Occurrence of Cerebral Venous Sinus Thrombosis in Patients with Presumed Idiopathic Intracranial Hypertension.Ophthalmology. 2006;113(12):2281–4.
  • 20. Benzimra JD, Simon S, Sinclair AJ, Mollan SP. Sight-Threatening pseudotumour cerebri associated with excess vitamin a supplementation. Pract Neurol .2015;15(1):72–3. 21.Lessell S. Pediatric pseudotumor cerebri (idiopathic intracranial hypertension). Survey of Ophthalmology. Surv Ophthalmol; 1992;37:155–66.
  • 22.Henry M, Driscoll MC, Miller M, Chang T, Minniti CP. Pseudotumor cerebri in children with sickle cell disease: a case series. Pediatrics 2004;113: 265-69.
  • 23.Avery RA, Shah SS, Licht DJ, Seiden JA, Huh JW, Boswinkel J, et al. Reference Range for Cerebrospinal Fluid Opening Pressure in Children. N Engl J Med .2010;363(9):891–3.
  • 24.Gospe SM, Bhatti MT, El-Dairi MA. Anatomic and visual function outcomes in paediatric idiopathic intracranial hypertension. Br J Ophthalmol .2016;100(4):505–9.
  • 25.Deǧerliyurt A, Teber S, Karakaya G, G uven A, Seker ED, Arhan EP, et al. Pseudotumor cerebri/idiopathic intracranial hypertension in children: An experience of a tertiary care hospital. Brain Dev .2014;36(8):690–9.
  • 26.Gocmen R, Konuskan B. Clinical and neurogoral findings of pseudotic umor cerebr in children. Kirikkale University Faculty of Medicine Journal. 2018 Apr 30 ;20(1):33–40.
  • .
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makaleleri
Yazarlar

Hülya İnce 0000-0002-8923-0413

Yayımlanma Tarihi 31 Ağustos 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 7 Sayı: 2

Kaynak Göster

Vancouver İnce H. Etiological Factors in Pediatric Pseudotumor Cerebri Cases. Middle Black Sea Journal of Health Science. 2021;7(2):198-204.

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