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Year 2004, Volume: 5 Issue: 2, 19 - 21, 01.08.2004

Abstract

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References

  • 1. MacKIE RM. An aid to the preoperative assessment of pigmented lesions of the skin. Br J Dermatol 1971; 85: 232-8.
  • 2. Hoegl L, Stolz W, Braun-Falco O. Historische Entwicklung derAuflichtmikroskopie. Hautarzt 1993; 44: 182-5.
  • 3. MacKIE RM. Skin surface microscopy. Turk J Dermatopathol 1992; 1: 80-1.
  • 4. Nilles M, Moedeher RH, Schille WB. Surface microscopy of naevi and melanomas. Br J Dermatol 1994; 130: 349-55.
  • 5. Soyer HP, Smolle J, Hodl S, Pachernegg H, Kerl H. Surface microscopy. A new approach to the diagnosis of cutaneous pigmented tumors. Am J Dermatopathol 1989; 11: 1-10.
  • 6. Nachbar F, Stolz W, Merkle T, Cognetta AB, Vogt T, Landthaler M, Bilek P, Braun-Falco O, Plewig G. The ABCD rule of dermatoscopy. J Am Acad Dermatol 1994; 30: 551-9.
  • 7. Stolz W, Landthaler M. Klassifikation, Diagnostik und Differentialdiagnostik des malignen Melanoms. Chirurg 1994; 64: 145-5.
  • 8. Rassner G. Früherkennung des malignen Melanoms der Haut. Hautarzt 1988; 39: 396-401.
  • 9. Schmoeckel C, Wagner-Grosser G, Braun-Falco O. Klinische Diagnostik initialer maligner Melanome. Hautarzt 1985; 36: 558-62.
  • 10. Braun-Falco O, Landthaler M, Holzel D, Konz B, Schmoeckel C. Klassifizierung, Diagnose und Differentialdiagnose maligner Melanome. Chirurg 1986; 57: 593-600.
  • 11. Weidner F, Hornstein OP, Bischof GM. Zur Treffsicherheit der klinischen Diagnose bei malignen Hautmelanomen. Dermatol Monatsschr 1983; 169: 706-10.
  • 12. Kopf AW, Mintzis M, Bart RS. Diagnostic accuracy in malignant melanoma.Arch Dermatol 1975; 111: 1291- 2.
  • 13. Grin CM, Kopf AW, Welkovich B, Bart RS, Levenstein MJ. Accuracy in the clinical diagnosis of malignant melanoma.Arch Dermatol 1990; 126: 763-6.
  • 14. Carli P, De Giorgi V, Naldi L, Dosi G. Reliability and inter-observer agreement of dermoscopic diagnosis of melanoma and melanocytic naevi. Eur J Cancer Prev 1998; 7: 397-402.
  • 15. Steiner A, Pehamberger H, Wolff K. In vivo epiluminescence microscopy of pigmented skin lesions. II. Diagnosis of small pigmented skin lesions and early melanoma. J Am Acad Dermatol 1987; 17: 584-91.
  • 16. Carli P, De Giorgi V, Giannotti B. Dermoscopy as a second step in the diagnosis of doubthful pigmented skin lesions: How great is the risk of missing a melanoma? J Eur Acad Dermatol Venereol 2001; 15: 24-26.
  • 17. Altman DG. Practical statistics for medical research. 1 ed. London: Chapman&Hall, 1995: 404.
  • 18. EDITORIAL. Skin surface microscopy: Anything new under the sun? Lancet I 1989: 1329.
  • 19. Onsun N, Atýlganoðlu U, Niþancý P, Kaner G, Kural Y, Çek D. Klinik olarak malin melanomu taklid eden lezyonlarýn ayýrýcý tanýsýnda dermatoskopi. XII. Prof.Dr.A.Lütfü Tat Simpozyumu Serbest Bildiriler Kitabý.Ankara:Ayrýntý ofset, 1995: 89-91.
  • 20. Atýlganoðlu U, Onsun N, Kaner G, Kural Y, Çek D. Dermatoskopi yöntemi erken evre melanom tanýsýný kolaylaþtýrýyor mu? XII. Prof.Dr.A.Lütfü Tat Simpozyumu Serbest Bildiriler Kitabý. Ankara: Ayrýntý ofset, 1995: 84-8.

Comparison of Dermoscopic and Histopathologic Diagnoses of Naevus Naevocellularis

Year 2004, Volume: 5 Issue: 2, 19 - 21, 01.08.2004

Abstract

Purpose: Differential diagnosis in melanocytic skin lesions is important in determining the treatment modality. In the past, histopathologic examination was mostly used for this aim. Recently, dermoscopy is widely used as an alternative noninvasive diagnostic method, so that it increases preoperative diagnostic accuracy. In this study our aim was to determine whether dermoscopy can substitute for histopathologic examination in the diagnosis of naevus naevocellularis. Materials and Methods: 25 naevus naevocellularis of 22 patients, who had admitted to our nevus follow-up clinic between September 1998-June 1999, were enrolled in this study. After dermoscopic and histopathologic examinations of all the lesions were completed, the concordance between dermoscopic and histopathologic diagnoses were evaluated. Manual dermoscope was used for routine dermoscopic examinations. Finally, dermoscopic photographs of the lesions were taken by Dermaphot. Kappa value was interpreted to assesss the agreement between dermoscopic and histopathologic methods. Results: Dermoscopic examination revealed 7 jonksiyonel nevus naevocellularis (NNC), 15 bileþik NNC, 3 intradermal NNC, where as histopathologic examination revealed 7 jonksiyonel NNC, 10 bileþik NNC, 8 intradermal NNC. Of the 25 lesions dermoscopically examined, the diagnoses of 20 (80%) were concordant with the histopathologic diagnoses. The agreement between dermoscopic and histopathologic methods was good (K value= 0.69).; Conclusion: Although dermoscopy is widely used as an alternative noninvasive diagnostic method in the differential diagnosis of melanocytic skin lesions recently, our results have led us to conclude that this popular method can not substitute for histopathologic examination in the diagnosis of naevus naevocellularis.

References

  • 1. MacKIE RM. An aid to the preoperative assessment of pigmented lesions of the skin. Br J Dermatol 1971; 85: 232-8.
  • 2. Hoegl L, Stolz W, Braun-Falco O. Historische Entwicklung derAuflichtmikroskopie. Hautarzt 1993; 44: 182-5.
  • 3. MacKIE RM. Skin surface microscopy. Turk J Dermatopathol 1992; 1: 80-1.
  • 4. Nilles M, Moedeher RH, Schille WB. Surface microscopy of naevi and melanomas. Br J Dermatol 1994; 130: 349-55.
  • 5. Soyer HP, Smolle J, Hodl S, Pachernegg H, Kerl H. Surface microscopy. A new approach to the diagnosis of cutaneous pigmented tumors. Am J Dermatopathol 1989; 11: 1-10.
  • 6. Nachbar F, Stolz W, Merkle T, Cognetta AB, Vogt T, Landthaler M, Bilek P, Braun-Falco O, Plewig G. The ABCD rule of dermatoscopy. J Am Acad Dermatol 1994; 30: 551-9.
  • 7. Stolz W, Landthaler M. Klassifikation, Diagnostik und Differentialdiagnostik des malignen Melanoms. Chirurg 1994; 64: 145-5.
  • 8. Rassner G. Früherkennung des malignen Melanoms der Haut. Hautarzt 1988; 39: 396-401.
  • 9. Schmoeckel C, Wagner-Grosser G, Braun-Falco O. Klinische Diagnostik initialer maligner Melanome. Hautarzt 1985; 36: 558-62.
  • 10. Braun-Falco O, Landthaler M, Holzel D, Konz B, Schmoeckel C. Klassifizierung, Diagnose und Differentialdiagnose maligner Melanome. Chirurg 1986; 57: 593-600.
  • 11. Weidner F, Hornstein OP, Bischof GM. Zur Treffsicherheit der klinischen Diagnose bei malignen Hautmelanomen. Dermatol Monatsschr 1983; 169: 706-10.
  • 12. Kopf AW, Mintzis M, Bart RS. Diagnostic accuracy in malignant melanoma.Arch Dermatol 1975; 111: 1291- 2.
  • 13. Grin CM, Kopf AW, Welkovich B, Bart RS, Levenstein MJ. Accuracy in the clinical diagnosis of malignant melanoma.Arch Dermatol 1990; 126: 763-6.
  • 14. Carli P, De Giorgi V, Naldi L, Dosi G. Reliability and inter-observer agreement of dermoscopic diagnosis of melanoma and melanocytic naevi. Eur J Cancer Prev 1998; 7: 397-402.
  • 15. Steiner A, Pehamberger H, Wolff K. In vivo epiluminescence microscopy of pigmented skin lesions. II. Diagnosis of small pigmented skin lesions and early melanoma. J Am Acad Dermatol 1987; 17: 584-91.
  • 16. Carli P, De Giorgi V, Giannotti B. Dermoscopy as a second step in the diagnosis of doubthful pigmented skin lesions: How great is the risk of missing a melanoma? J Eur Acad Dermatol Venereol 2001; 15: 24-26.
  • 17. Altman DG. Practical statistics for medical research. 1 ed. London: Chapman&Hall, 1995: 404.
  • 18. EDITORIAL. Skin surface microscopy: Anything new under the sun? Lancet I 1989: 1329.
  • 19. Onsun N, Atýlganoðlu U, Niþancý P, Kaner G, Kural Y, Çek D. Klinik olarak malin melanomu taklid eden lezyonlarýn ayýrýcý tanýsýnda dermatoskopi. XII. Prof.Dr.A.Lütfü Tat Simpozyumu Serbest Bildiriler Kitabý.Ankara:Ayrýntý ofset, 1995: 89-91.
  • 20. Atýlganoðlu U, Onsun N, Kaner G, Kural Y, Çek D. Dermatoskopi yöntemi erken evre melanom tanýsýný kolaylaþtýrýyor mu? XII. Prof.Dr.A.Lütfü Tat Simpozyumu Serbest Bildiriler Kitabý. Ankara: Ayrýntý ofset, 1995: 84-8.
There are 20 citations in total.

Details

Other ID JA43GJ85JC
Journal Section Research Article
Authors

Mustafa Turhan Şahin This is me

Aylin TÜREL Ermertcan This is me

İşıl İnanır This is me

Mehmet Akif Demir This is me

Serap Öztürkcan This is me

Publication Date August 1, 2004
Published in Issue Year 2004 Volume: 5 Issue: 2

Cite

EndNote Şahin MT, Ermertcan AT, İnanır İ, Demir MA, Öztürkcan S (August 1, 2004) Comparison of Dermoscopic and Histopathologic Diagnoses of Naevus Naevocellularis. Meandros Medical And Dental Journal 5 2 19–21.