Diagnosis of Systemic Lupus Erythematosus in a Patient with Generalized Lymphadenopathy: A Case Report

Year 2011, Volume: 12 Issue: 2, 45 - 47, 01.08.2011

İbrahim Halil Türkbeyler Yavuz Pehlivan Gazi Çömez Orhan Zengin Fatih Göktepe Ahmet Mesut Onat

Abstract

Lymphadenopathy (LAP) is defined as abnormality in the size and character of lymph node. Lymphadenopathy emerges due to increase of inflammatory cells in lymph node or invasion of these cells in the lymph node. Lymphadenopathy can occur in any age group, in symptomatic or asymptomatic patients, and in a single site or at multiple sites. Causes of generalized lymphadenopathy include infections, autoimmune diseases, malignancies, histiocytoses, storage diseases, benign hyperplasia, and drug reactions. In LAP etiology, collagen tissue diseases hold an important place. The most common autoimmune causes of LAP are rheumatoid arthritis, systemic lupus erythematosus (SLE) and Sjogren syndrome. In this case, we presented a case who was researched for generalized lymphadenopathy and diagnosed with SLE. SLE diagnosis should be considered in patients researched for lymphadenopathy etiology.

Keywords

Lymphadenopathy, systemic lupus erythematosus

YAYGIN LENFADENOPATİ NEDENİ İLE BAŞVURAN HASTADA SİSTEMİK LUPUS ERİTEMATOZİS TANISI: OLGU SUNUMU

Abstract

Lenfadenopati (LAP), lenf düğümünün boyut ve karakterindeki anormallik olarak tanımlanır. Lenfadenopatineoplastik veya inflamatuar hücrelerin lenf nodunda çoğalması veya lenf nodunu invazyonu sonucu oluşabilir.Lenfadenopati geniş bir hastalık tablosu sonucunda gelişebilir. Yaygın lenfadenopati sebepleri arasındaenfeksiyonlar, otoimmun hastalıklar, malignensiler, histiyositozlar, depo hastalıkları, hiperplaziler ve ilaçetkileşimleri sayılabilir. Lenfadenopati etyolojisinde kollajen doku hastalıkları önemli yer tutmaktadır. En sıklenfadenopatiye neden olan otoimmun hastalıklar romatoid artrit, sistemik lupus eritematozis (SLE) ve Sjögrensendromudur. Bu olguda yaygın lenfadenopati nedeni ile araştırılan ve SLE tanısı alan bir olguyu sunduk.Lenfadenopati nedeniyle tetkik edilen hastalarda kollajen doku hastalıklarını ve özellikle de SLE'u göz önündebulundurmamız gerektiğini bu yazıda vurgulamak istedik

Keywords

Lenfadenopati, sistemik lupus eritematozis, başlangıç semptom

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